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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NCF1C
Full Name:
Putative neutrophil cytosol factor 1C
Alias:
SH3PXD1C
Type:
Regulatory protein - NADPH oxidase activator
Mass (Da):
41851
Number AA:
366
UniProt ID:
A8MVU1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
V
K
W
Q
D
L
S
E
K
V
V
Y
R
R
Site 2
Y17
D
L
S
E
K
V
V
Y
R
R
F
T
E
I
Y
Site 3
T21
K
V
V
Y
R
R
F
T
E
I
Y
E
F
H
K
Site 4
Y24
Y
R
R
F
T
E
I
Y
E
F
H
K
T
L
K
Site 5
T29
E
I
Y
E
F
H
K
T
L
K
E
M
F
P
I
Site 6
T71
E
N
H
Q
G
T
L
T
E
Y
C
S
T
L
M
Site 7
Y73
H
Q
G
T
L
T
E
Y
C
S
T
L
M
S
L
Site 8
T76
T
L
T
E
Y
C
S
T
L
M
S
L
P
T
K
Site 9
S79
E
Y
C
S
T
L
M
S
L
P
T
K
I
S
R
Site 10
T82
S
T
L
M
S
L
P
T
K
I
S
R
C
P
H
Site 11
S85
M
S
L
P
T
K
I
S
R
C
P
H
L
L
D
Site 12
T109
K
L
P
T
D
N
Q
T
K
K
P
E
T
Y
L
Site 13
Y115
Q
T
K
K
P
E
T
Y
L
M
P
K
D
G
K
Site 14
S123
L
M
P
K
D
G
K
S
T
A
T
D
I
T
G
Site 15
Y143
T
Y
R
A
I
A
D
Y
E
K
T
S
G
S
E
Site 16
S149
D
Y
E
K
T
S
G
S
E
M
A
L
S
T
G
Site 17
S184
K
R
G
W
I
P
A
S
F
L
E
P
L
D
S
Site 18
S191
S
F
L
E
P
L
D
S
P
D
E
T
E
D
P
Site 19
T195
P
L
D
S
P
D
E
T
E
D
P
E
P
N
Y
Site 20
Y202
T
E
D
P
E
P
N
Y
A
G
E
P
Y
V
A
Site 21
Y207
P
N
Y
A
G
E
P
Y
V
A
I
K
A
Y
T
Site 22
Y213
P
Y
V
A
I
K
A
Y
T
A
V
E
G
D
E
Site 23
T248
V
I
R
K
D
D
V
T
G
Y
F
P
S
M
Y
Site 24
Y250
R
K
D
D
V
T
G
Y
F
P
S
M
Y
L
Q
Site 25
S253
D
V
T
G
Y
F
P
S
M
Y
L
Q
K
S
G
Site 26
Y255
T
G
Y
F
P
S
M
Y
L
Q
K
S
G
Q
D
Site 27
S259
P
S
M
Y
L
Q
K
S
G
Q
D
V
S
Q
A
Site 28
S264
Q
K
S
G
Q
D
V
S
Q
A
Q
R
Q
I
K
Site 29
S279
R
G
A
P
P
R
R
S
S
I
R
N
A
H
S
Site 30
S280
G
A
P
P
R
R
S
S
I
R
N
A
H
S
I
Site 31
S286
S
S
I
R
N
A
H
S
I
H
Q
R
S
R
K
Site 32
S291
A
H
S
I
H
Q
R
S
R
K
R
L
S
Q
D
Site 33
S296
Q
R
S
R
K
R
L
S
Q
D
A
Y
R
R
N
Site 34
Y300
K
R
L
S
Q
D
A
Y
R
R
N
S
V
R
F
Site 35
S304
Q
D
A
Y
R
R
N
S
V
R
F
L
Q
Q
R
Site 36
S321
Q
A
R
P
G
P
Q
S
P
G
S
P
L
E
E
Site 37
S324
P
G
P
Q
S
P
G
S
P
L
E
E
E
R
Q
Site 38
T332
P
L
E
E
E
R
Q
T
Q
R
S
K
P
Q
P
Site 39
S335
E
E
R
Q
T
Q
R
S
K
P
Q
P
A
V
P
Site 40
S346
P
A
V
P
P
R
P
S
A
D
L
I
L
N
R
Site 41
S355
D
L
I
L
N
R
C
S
E
S
T
K
R
K
L
Site 42
S357
I
L
N
R
C
S
E
S
T
K
R
K
L
A
S
Site 43
T358
L
N
R
C
S
E
S
T
K
R
K
L
A
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation