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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM171A2
Full Name:
Protein FAM171A2
Alias:
Family with sequence similarity 171, member A2; MGC34829
Type:
Mass (Da):
87417
Number AA:
826
UniProt ID:
A8MVW0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
G
L
L
L
G
S
A
S
R
A
P
G
K
S
P
Site 2
S357
Q
H
R
K
L
Q
L
S
G
P
S
D
G
N
K
Site 3
T369
G
N
K
R
D
Q
A
T
S
M
S
Q
L
H
L
Site 4
S370
N
K
R
D
Q
A
T
S
M
S
Q
L
H
L
I
Site 5
S372
R
D
Q
A
T
S
M
S
Q
L
H
L
I
C
G
Site 6
S387
G
P
L
E
P
A
P
S
G
D
P
E
A
P
P
Site 7
S400
P
P
P
G
P
L
H
S
A
F
S
S
S
R
D
Site 8
S403
G
P
L
H
S
A
F
S
S
S
R
D
L
A
S
Site 9
S404
P
L
H
S
A
F
S
S
S
R
D
L
A
S
S
Site 10
S405
L
H
S
A
F
S
S
S
R
D
L
A
S
S
R
Site 11
S410
S
S
S
R
D
L
A
S
S
R
D
D
F
F
R
Site 12
S411
S
S
R
D
L
A
S
S
R
D
D
F
F
R
T
Site 13
T418
S
R
D
D
F
F
R
T
K
P
R
S
A
S
R
Site 14
S422
F
F
R
T
K
P
R
S
A
S
R
P
A
A
E
Site 15
S424
R
T
K
P
R
S
A
S
R
P
A
A
E
P
S
Site 16
S431
S
R
P
A
A
E
P
S
G
A
R
G
G
E
S
Site 17
S438
S
G
A
R
G
G
E
S
A
G
L
K
G
A
R
Site 18
S446
A
G
L
K
G
A
R
S
A
E
G
P
G
G
L
Site 19
S465
E
E
H
R
R
G
P
S
G
A
A
A
F
L
H
Site 20
S476
A
F
L
H
E
P
P
S
P
P
P
P
F
D
H
Site 21
Y484
P
P
P
P
F
D
H
Y
L
G
H
K
G
A
A
Site 22
T495
K
G
A
A
E
G
K
T
P
D
F
L
L
S
Q
Site 23
S501
K
T
P
D
F
L
L
S
Q
S
V
D
Q
L
A
Site 24
S503
P
D
F
L
L
S
Q
S
V
D
Q
L
A
R
P
Site 25
S512
D
Q
L
A
R
P
P
S
L
G
Q
A
G
Q
L
Site 26
Y533
D
H
L
K
D
N
V
Y
R
N
V
M
P
T
L
Site 27
S590
R
P
Q
M
P
G
H
S
G
P
G
G
E
G
G
Site 28
T638
N
G
E
L
Q
A
L
T
E
K
K
L
L
E
L
Site 29
S657
H
P
R
A
W
F
V
S
L
D
G
R
S
N
S
Site 30
S662
F
V
S
L
D
G
R
S
N
S
Q
V
R
H
S
Site 31
S664
S
L
D
G
R
S
N
S
Q
V
R
H
S
Y
I
Site 32
S669
S
N
S
Q
V
R
H
S
Y
I
D
L
Q
A
G
Site 33
Y670
N
S
Q
V
R
H
S
Y
I
D
L
Q
A
G
G
Site 34
S681
Q
A
G
G
G
A
R
S
T
D
A
S
L
D
S
Site 35
T682
A
G
G
G
A
R
S
T
D
A
S
L
D
S
G
Site 36
S685
G
A
R
S
T
D
A
S
L
D
S
G
V
D
V
Site 37
S688
S
T
D
A
S
L
D
S
G
V
D
V
H
E
A
Site 38
S727
A
P
P
R
L
A
L
S
E
D
T
E
P
S
S
Site 39
T730
R
L
A
L
S
E
D
T
E
P
S
S
S
E
S
Site 40
S733
L
S
E
D
T
E
P
S
S
S
E
S
R
T
G
Site 41
S734
S
E
D
T
E
P
S
S
S
E
S
R
T
G
L
Site 42
S735
E
D
T
E
P
S
S
S
E
S
R
T
G
L
C
Site 43
S737
T
E
P
S
S
S
E
S
R
T
G
L
C
S
P
Site 44
T739
P
S
S
S
E
S
R
T
G
L
C
S
P
E
D
Site 45
S743
E
S
R
T
G
L
C
S
P
E
D
N
S
L
T
Site 46
S748
L
C
S
P
E
D
N
S
L
T
P
L
L
D
E
Site 47
T750
S
P
E
D
N
S
L
T
P
L
L
D
E
V
A
Site 48
T765
A
P
E
G
R
A
A
T
V
P
R
G
R
G
R
Site 49
S773
V
P
R
G
R
G
R
S
R
G
D
S
S
R
S
Site 50
S777
R
G
R
S
R
G
D
S
S
R
S
S
A
S
E
Site 51
S778
G
R
S
R
G
D
S
S
R
S
S
A
S
E
L
Site 52
S780
S
R
G
D
S
S
R
S
S
A
S
E
L
R
R
Site 53
S781
R
G
D
S
S
R
S
S
A
S
E
L
R
R
D
Site 54
S783
D
S
S
R
S
S
A
S
E
L
R
R
D
S
L
Site 55
S789
A
S
E
L
R
R
D
S
L
T
S
P
E
D
E
Site 56
T791
E
L
R
R
D
S
L
T
S
P
E
D
E
L
G
Site 57
S792
L
R
R
D
S
L
T
S
P
E
D
E
L
G
A
Site 58
S810
D
E
A
G
D
K
K
S
P
W
Q
R
R
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation