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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMCO5B
Full Name:
Transmembrane and coiled-coil domain-containing protein 5B
Alias:
Type:
Mass (Da):
35763
Number AA:
307
UniProt ID:
A8MYB1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
Q
N
L
D
C
L
N
S
D
L
E
K
D
L
Q
Site 2
T59
K
I
K
E
K
E
E
T
I
S
S
L
E
R
K
Site 3
S61
K
E
K
E
E
T
I
S
S
L
E
R
K
L
A
Site 4
S62
E
K
E
E
T
I
S
S
L
E
R
K
L
A
L
Site 5
S70
L
E
R
K
L
A
L
S
L
E
E
A
K
E
E
Site 6
Y82
K
E
E
E
E
L
N
Y
V
I
D
E
Q
E
E
Site 7
S90
V
I
D
E
Q
E
E
S
L
R
E
L
E
L
E
Site 8
S104
E
T
A
K
L
E
K
S
N
A
I
L
S
R
N
Site 9
T124
K
K
I
S
G
L
F
T
N
I
G
L
E
E
E
Site 10
T133
I
G
L
E
E
E
T
T
K
Q
I
L
E
E
M
Site 11
S147
M
K
A
R
L
Q
K
S
T
E
S
C
A
K
Q
Site 12
T148
K
A
R
L
Q
K
S
T
E
S
C
A
K
Q
E
Site 13
S163
E
E
L
A
K
I
E
S
D
Y
Q
S
V
S
D
Site 14
Y165
L
A
K
I
E
S
D
Y
Q
S
V
S
D
L
C
Site 15
S167
K
I
E
S
D
Y
Q
S
V
S
D
L
C
K
D
Site 16
S169
E
S
D
Y
Q
S
V
S
D
L
C
K
D
Q
V
Site 17
Y177
D
L
C
K
D
Q
V
Y
Y
I
K
K
Y
Q
E
Site 18
Y182
Q
V
Y
Y
I
K
K
Y
Q
E
V
L
R
K
M
Site 19
T195
K
M
K
E
E
K
E
T
L
L
L
E
K
Q
I
Site 20
S203
L
L
L
E
K
Q
I
S
K
A
Q
D
D
S
S
Site 21
S210
S
K
A
Q
D
D
S
S
Q
T
V
K
P
G
S
Site 22
T212
A
Q
D
D
S
S
Q
T
V
K
P
G
S
I
L
Site 23
S217
S
Q
T
V
K
P
G
S
I
L
A
D
T
T
Q
Site 24
T222
P
G
S
I
L
A
D
T
T
Q
R
N
M
E
R
Site 25
T223
G
S
I
L
A
D
T
T
Q
R
N
M
E
R
T
Site 26
T230
T
Q
R
N
M
E
R
T
T
I
K
K
Q
E
R
Site 27
T231
Q
R
N
M
E
R
T
T
I
K
K
Q
E
R
R
Site 28
S288
L
S
R
G
T
L
E
S
L
R
K
V
S
H
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation