KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KCNU1
Full Name:
Potassium channel subfamily U member 1
Alias:
Calcium-activated potassium channel subunit alpha-3;Calcium-activated potassium channel, subfamily M subunit alpha-3;KCa5;Slowpoke homolog 3
Type:
Mass (Da):
129543
Number AA:
1149
UniProt ID:
A8MYU2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
Q
T
K
L
R
N
E
T
W
E
D
L
P
K
M
Site 2
T72
L
E
L
F
T
S
G
T
I
A
R
S
H
V
R
Site 3
S76
T
S
G
T
I
A
R
S
H
V
R
S
L
H
F
Site 4
S80
I
A
R
S
H
V
R
S
L
H
F
Q
G
Q
F
Site 5
S130
N
S
A
D
P
V
G
S
C
S
S
Y
E
D
K
Site 6
S133
D
P
V
G
S
C
S
S
Y
E
D
K
T
I
P
Site 7
Y134
P
V
G
S
C
S
S
Y
E
D
K
T
I
P
I
Site 8
Y187
P
P
T
F
I
S
Y
Y
L
K
S
N
W
L
G
Site 9
T218
Q
I
L
R
A
I
K
T
S
N
S
V
K
F
S
Site 10
S219
I
L
R
A
I
K
T
S
N
S
V
K
F
S
K
Site 11
S221
R
A
I
K
T
S
N
S
V
K
F
S
K
L
L
Site 12
S248
F
I
H
L
V
E
N
S
G
D
P
W
L
K
G
Site 13
S258
P
W
L
K
G
R
N
S
Q
N
I
S
Y
F
E
Site 14
S262
G
R
N
S
Q
N
I
S
Y
F
E
S
I
Y
L
Site 15
Y263
R
N
S
Q
N
I
S
Y
F
E
S
I
Y
L
V
Site 16
Y321
L
F
A
N
K
R
K
Y
T
S
S
Y
E
A
L
Site 17
T322
F
A
N
K
R
K
Y
T
S
S
Y
E
A
L
K
Site 18
S324
N
K
R
K
Y
T
S
S
Y
E
A
L
K
G
K
Site 19
Y325
K
R
K
Y
T
S
S
Y
E
A
L
K
G
K
K
Site 20
S357
R
N
F
L
R
D
K
S
G
E
I
N
T
E
I
Site 21
S422
A
N
P
L
C
S
D
S
H
A
E
D
I
S
N
Site 22
S428
D
S
H
A
E
D
I
S
N
I
M
R
V
L
S
Site 23
S435
S
N
I
M
R
V
L
S
I
K
N
Y
D
S
T
Site 24
Y439
R
V
L
S
I
K
N
Y
D
S
T
T
R
I
I
Site 25
S441
L
S
I
K
N
Y
D
S
T
T
R
I
I
I
Q
Site 26
T442
S
I
K
N
Y
D
S
T
T
R
I
I
I
Q
I
Site 27
Y457
L
Q
S
H
N
K
V
Y
L
P
K
I
P
S
W
Site 28
T527
S
M
K
N
K
I
L
T
Q
R
L
S
D
D
F
Site 29
S531
K
I
L
T
Q
R
L
S
D
D
F
A
G
M
S
Site 30
S538
S
D
D
F
A
G
M
S
F
P
E
V
A
R
L
Site 31
T584
Q
V
R
I
R
K
N
T
L
G
F
F
I
A
E
Site 32
T592
L
G
F
F
I
A
E
T
P
K
D
V
R
R
A
Site 33
Y602
D
V
R
R
A
L
F
Y
C
S
V
C
H
D
D
Site 34
T630
S
R
S
R
Q
H
I
T
V
P
S
V
K
R
M
Site 35
S645
K
K
C
L
K
G
I
S
S
R
I
S
G
Q
D
Site 36
S646
K
C
L
K
G
I
S
S
R
I
S
G
Q
D
S
Site 37
S649
K
G
I
S
S
R
I
S
G
Q
D
S
P
P
R
Site 38
S653
S
R
I
S
G
Q
D
S
P
P
R
V
S
A
S
Site 39
S658
Q
D
S
P
P
R
V
S
A
S
T
S
S
I
S
Site 40
S660
S
P
P
R
V
S
A
S
T
S
S
I
S
N
F
Site 41
T661
P
P
R
V
S
A
S
T
S
S
I
S
N
F
T
Site 42
S662
P
R
V
S
A
S
T
S
S
I
S
N
F
T
T
Site 43
S663
R
V
S
A
S
T
S
S
I
S
N
F
T
T
R
Site 44
T668
T
S
S
I
S
N
F
T
T
R
T
L
Q
H
D
Site 45
T669
S
S
I
S
N
F
T
T
R
T
L
Q
H
D
V
Site 46
S680
Q
H
D
V
E
Q
D
S
D
Q
L
D
S
S
G
Site 47
T701
P
T
S
L
D
K
V
T
L
K
R
T
G
K
S
Site 48
S708
T
L
K
R
T
G
K
S
K
Y
K
F
R
N
H
Site 49
Y710
K
R
T
G
K
S
K
Y
K
F
R
N
H
I
V
Site 50
S726
C
V
F
G
D
A
H
S
A
P
M
G
L
R
N
Site 51
S741
F
V
M
P
L
R
A
S
N
Y
T
R
K
E
L
Site 52
Y743
M
P
L
R
A
S
N
Y
T
R
K
E
L
K
D
Site 53
Y759
V
F
I
G
S
L
D
Y
L
Q
R
E
W
R
F
Site 54
S801
C
S
M
C
A
V
L
S
P
P
P
Q
P
S
S
Site 55
S807
L
S
P
P
P
Q
P
S
S
N
Q
T
L
V
D
Site 56
S808
S
P
P
P
Q
P
S
S
N
Q
T
L
V
D
T
Site 57
T811
P
Q
P
S
S
N
Q
T
L
V
D
T
E
A
I
Site 58
S831
I
G
S
L
Q
I
D
S
S
S
D
P
S
P
S
Site 59
S832
G
S
L
Q
I
D
S
S
S
D
P
S
P
S
V
Site 60
S833
S
L
Q
I
D
S
S
S
D
P
S
P
S
V
S
Site 61
S836
I
D
S
S
S
D
P
S
P
S
V
S
E
E
T
Site 62
S838
S
S
S
D
P
S
P
S
V
S
E
E
T
P
G
Site 63
S840
S
D
P
S
P
S
V
S
E
E
T
P
G
Y
T
Site 64
T843
S
P
S
V
S
E
E
T
P
G
Y
T
N
G
H
Site 65
Y846
V
S
E
E
T
P
G
Y
T
N
G
H
N
E
K
Site 66
T863
C
R
K
V
P
I
L
T
E
L
K
N
P
S
N
Site 67
S883
Q
L
G
G
L
E
G
S
L
Q
E
T
N
L
H
Site 68
T887
L
E
G
S
L
Q
E
T
N
L
H
L
S
T
A
Site 69
S892
Q
E
T
N
L
H
L
S
T
A
F
S
T
G
T
Site 70
Y945
H
L
D
K
D
K
V
Y
G
V
A
D
S
C
T
Site 71
T952
Y
G
V
A
D
S
C
T
S
L
L
S
G
R
N
Site 72
S953
G
V
A
D
S
C
T
S
L
L
S
G
R
N
R
Site 73
S956
D
S
C
T
S
L
L
S
G
R
N
R
C
K
L
Site 74
S974
S
L
H
E
T
I
L
S
D
V
N
P
R
N
T
Site 75
T981
S
D
V
N
P
R
N
T
F
G
Q
L
F
C
G
Site 76
Y1044
I
P
F
S
T
A
C
Y
K
R
N
E
E
F
S
Site 77
S1051
Y
K
R
N
E
E
F
S
L
Q
K
S
Y
E
I
Site 78
S1055
E
E
F
S
L
Q
K
S
Y
E
I
V
N
K
A
Site 79
S1063
Y
E
I
V
N
K
A
S
Q
T
T
E
T
H
S
Site 80
S1070
S
Q
T
T
E
T
H
S
D
T
N
C
P
P
T
Site 81
T1072
T
T
E
T
H
S
D
T
N
C
P
P
T
I
D
Site 82
T1077
S
D
T
N
C
P
P
T
I
D
S
V
T
E
T
Site 83
S1080
N
C
P
P
T
I
D
S
V
T
E
T
L
Y
S
Site 84
T1082
P
P
T
I
D
S
V
T
E
T
L
Y
S
P
V
Site 85
T1084
T
I
D
S
V
T
E
T
L
Y
S
P
V
Y
S
Site 86
Y1086
D
S
V
T
E
T
L
Y
S
P
V
Y
S
Y
Q
Site 87
S1087
S
V
T
E
T
L
Y
S
P
V
Y
S
Y
Q
P
Site 88
Y1090
E
T
L
Y
S
P
V
Y
S
Y
Q
P
R
T
N
Site 89
S1091
T
L
Y
S
P
V
Y
S
Y
Q
P
R
T
N
S
Site 90
Y1092
L
Y
S
P
V
Y
S
Y
Q
P
R
T
N
S
L
Site 91
T1096
V
Y
S
Y
Q
P
R
T
N
S
L
S
F
P
K
Site 92
S1098
S
Y
Q
P
R
T
N
S
L
S
F
P
K
Q
I
Site 93
S1100
Q
P
R
T
N
S
L
S
F
P
K
Q
I
A
W
Site 94
S1110
K
Q
I
A
W
N
Q
S
R
T
N
S
I
I
S
Site 95
T1112
I
A
W
N
Q
S
R
T
N
S
I
I
S
S
Q
Site 96
S1114
W
N
Q
S
R
T
N
S
I
I
S
S
Q
I
P
Site 97
S1118
R
T
N
S
I
I
S
S
Q
I
P
L
G
D
N
Site 98
T1133
A
K
E
N
E
R
K
T
S
D
E
V
Y
D
E
Site 99
S1134
K
E
N
E
R
K
T
S
D
E
V
Y
D
E
D
Site 100
Y1138
R
K
T
S
D
E
V
Y
D
E
D
P
F
A
Y
Site 101
Y1145
Y
D
E
D
P
F
A
Y
S
E
P
L
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation