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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXO6
Full Name:
Forkhead box protein O6
Alias:
Forkhead box O6; Forkhead box protein o6; Foxo6; FOXO6 Transcriptional activator
Type:
Uncharacterized protein
Mass (Da):
50595
Number AA:
492
UniProt ID:
A8MYZ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
D
P
D
F
A
P
Q
S
R
P
R
S
C
T
W
Site 2
S24
A
P
Q
S
R
P
R
S
C
T
W
P
L
P
Q
Site 3
T26
Q
S
R
P
R
S
C
T
W
P
L
P
Q
P
D
Site 4
T60
C
G
P
E
R
R
A
T
A
P
A
M
A
P
A
Site 5
S82
G
P
L
R
K
A
K
S
S
R
R
N
A
W
G
Site 6
S83
P
L
R
K
A
K
S
S
R
R
N
A
W
G
N
Site 7
S92
R
N
A
W
G
N
L
S
Y
A
D
L
I
T
K
Site 8
S103
L
I
T
K
A
I
E
S
A
P
D
K
R
L
T
Site 9
T110
S
A
P
D
K
R
L
T
L
S
Q
I
Y
D
W
Site 10
Y121
I
Y
D
W
M
V
R
Y
V
P
Y
F
K
D
K
Site 11
Y124
W
M
V
R
Y
V
P
Y
F
K
D
K
G
D
S
Site 12
S131
Y
F
K
D
K
G
D
S
N
S
S
A
G
W
K
Site 13
S133
K
D
K
G
D
S
N
S
S
A
G
W
K
N
S
Site 14
S140
S
S
A
G
W
K
N
S
I
R
H
N
L
S
L
Site 15
S146
N
S
I
R
H
N
L
S
L
H
T
R
F
I
R
Site 16
T174
L
N
P
E
G
G
K
T
G
K
T
P
R
R
R
Site 17
T177
E
G
G
K
T
G
K
T
P
R
R
R
A
V
S
Site 18
S184
T
P
R
R
R
A
V
S
M
D
N
G
A
K
F
Site 19
S210
Q
L
Q
A
P
E
R
S
P
D
D
S
S
P
S
Site 20
S214
P
E
R
S
P
D
D
S
S
P
S
A
P
A
P
Site 21
S215
E
R
S
P
D
D
S
S
P
S
A
P
A
P
G
Site 22
S217
S
P
D
D
S
S
P
S
A
P
A
P
G
P
V
Site 23
S233
A
A
A
K
W
A
A
S
P
A
S
H
A
S
D
Site 24
S236
K
W
A
A
S
P
A
S
H
A
S
D
D
Y
E
Site 25
S239
A
S
P
A
S
H
A
S
D
D
Y
E
A
W
A
Site 26
Y242
A
S
H
A
S
D
D
Y
E
A
W
A
D
F
R
Site 27
S281
S
S
P
L
M
Y
P
S
P
A
S
A
L
S
P
Site 28
S287
P
S
P
A
S
A
L
S
P
A
L
G
S
R
C
Site 29
Y330
L
D
G
A
Q
D
A
Y
G
P
R
P
A
P
R
Site 30
Y365
P
G
K
G
A
A
P
Y
A
P
P
A
P
S
R
Site 31
S371
P
Y
A
P
P
A
P
S
R
S
A
L
A
H
P
Site 32
S373
A
P
P
A
P
S
R
S
A
L
A
H
P
I
S
Site 33
S445
D
L
D
M
F
S
G
S
L
E
C
D
V
E
S
Site 34
S470
E
M
D
F
N
F
D
S
A
L
P
P
P
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation