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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KPNA7
Full Name:
Importin subunit alpha-8
Alias:
Karyopherin subunit alpha-7
Type:
Cytoplasm, Nuclear pore protein
Mass (Da):
56938
Number AA:
516
UniProt ID:
A9QM74
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006606
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T3
_
_
_
_
_
M
P
T
L
D
A
P
E
E
R
Site 2
Y16
E
R
R
R
K
F
K
Y
R
G
K
D
V
S
L
Site 3
S22
K
Y
R
G
K
D
V
S
L
R
R
Q
Q
R
M
Site 4
T44
K
A
K
K
D
E
Q
T
L
K
R
R
N
I
T
Site 5
T51
T
L
K
R
R
N
I
T
S
F
C
P
D
T
P
Site 6
S52
L
K
R
R
N
I
T
S
F
C
P
D
T
P
S
Site 7
T57
I
T
S
F
C
P
D
T
P
S
E
K
T
A
K
Site 8
S59
S
F
C
P
D
T
P
S
E
K
T
A
K
G
V
Site 9
S99
Q
T
A
R
K
M
L
S
Q
E
K
N
P
P
L
Site 10
S143
W
A
L
T
N
I
A
S
G
T
S
E
Q
T
R
Site 11
T196
E
F
R
D
N
V
I
T
S
N
A
I
P
H
L
Site 12
Y233
L
C
R
N
K
N
P
Y
P
C
D
T
A
V
K
Site 13
S255
H
L
L
Q
H
Q
D
S
E
V
L
S
D
A
C
Site 14
S259
H
Q
D
S
E
V
L
S
D
A
C
W
A
L
S
Site 15
S266
S
D
A
C
W
A
L
S
Y
L
T
D
G
S
N
Site 16
Y267
D
A
C
W
A
L
S
Y
L
T
D
G
S
N
K
Site 17
S272
L
S
Y
L
T
D
G
S
N
K
R
I
G
Q
V
Site 18
T301
S
S
E
L
N
V
L
T
P
S
L
R
T
V
G
Site 19
S303
E
L
N
V
L
T
P
S
L
R
T
V
G
N
I
Site 20
S477
E
N
R
Q
I
G
Q
S
A
L
N
I
I
E
K
Site 21
S493
F
G
E
E
E
D
E
S
Q
T
L
L
S
Q
V
Site 22
S498
D
E
S
Q
T
L
L
S
Q
V
I
D
Q
D
Y
Site 23
Y505
S
Q
V
I
D
Q
D
Y
E
F
I
D
Y
E
C
Site 24
Y510
Q
D
Y
E
F
I
D
Y
E
C
L
A
K
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation