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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C20orf82
Full Name:
Isthmin-1
Alias:
ISM; Isthmin
Type:
Uncharacterized protein
Mass (Da):
52107
Number AA:
464
UniProt ID:
B1AKI9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
H
I
T
V
L
R
G
S
G
A
A
D
G
P
D
Site 2
S53
Q
N
N
L
N
V
G
S
D
T
T
S
E
T
S
Site 3
T55
N
L
N
V
G
S
D
T
T
S
E
T
S
F
S
Site 4
T56
L
N
V
G
S
D
T
T
S
E
T
S
F
S
L
Site 5
S57
N
V
G
S
D
T
T
S
E
T
S
F
S
L
S
Site 6
S60
S
D
T
T
S
E
T
S
F
S
L
S
K
E
A
Site 7
S62
T
T
S
E
T
S
F
S
L
S
K
E
A
P
R
Site 8
S64
S
E
T
S
F
S
L
S
K
E
A
P
R
E
H
Site 9
T90
R
P
R
F
R
Q
E
T
G
H
P
S
L
Q
R
Site 10
S94
R
Q
E
T
G
H
P
S
L
Q
R
D
F
P
R
Site 11
S102
L
Q
R
D
F
P
R
S
F
L
L
D
L
P
N
Site 12
S114
L
P
N
F
P
D
L
S
K
A
D
I
N
G
Q
Site 13
S137
E
V
V
D
G
P
D
S
E
A
D
K
D
Q
H
Site 14
S150
Q
H
P
E
N
K
P
S
W
S
V
P
S
P
D
Site 15
S152
P
E
N
K
P
S
W
S
V
P
S
P
D
W
R
Site 16
S167
A
W
W
Q
R
S
L
S
L
A
R
A
N
S
G
Site 17
S173
L
S
L
A
R
A
N
S
G
D
Q
D
Y
K
Y
Site 18
Y178
A
N
S
G
D
Q
D
Y
K
Y
D
S
T
S
D
Site 19
Y180
S
G
D
Q
D
Y
K
Y
D
S
T
S
D
D
S
Site 20
S182
D
Q
D
Y
K
Y
D
S
T
S
D
D
S
N
F
Site 21
T183
Q
D
Y
K
Y
D
S
T
S
D
D
S
N
F
L
Site 22
S184
D
Y
K
Y
D
S
T
S
D
D
S
N
F
L
N
Site 23
S187
Y
D
S
T
S
D
D
S
N
F
L
N
P
P
R
Site 24
T199
P
P
R
G
W
D
H
T
A
P
G
H
R
T
F
Site 25
T205
H
T
A
P
G
H
R
T
F
E
T
K
D
Q
P
Site 26
Y214
E
T
K
D
Q
P
E
Y
D
S
T
D
G
E
G
Site 27
S216
K
D
Q
P
E
Y
D
S
T
D
G
E
G
D
W
Site 28
T217
D
Q
P
E
Y
D
S
T
D
G
E
G
D
W
S
Site 29
S243
G
N
Q
K
R
T
R
S
C
G
Y
A
C
T
A
Site 30
T267
N
C
P
G
I
E
D
T
F
R
T
A
A
T
E
Site 31
S276
R
T
A
A
T
E
V
S
L
L
A
G
S
E
E
Site 32
T287
G
S
E
E
F
N
A
T
K
L
F
E
V
D
T
Site 33
Y311
K
S
E
F
L
K
K
Y
M
H
K
V
M
N
D
Site 34
S321
K
V
M
N
D
L
P
S
C
P
C
S
Y
P
T
Site 35
S325
D
L
P
S
C
P
C
S
Y
P
T
E
V
A
Y
Site 36
Y326
L
P
S
C
P
C
S
Y
P
T
E
V
A
Y
S
Site 37
T328
S
C
P
C
S
Y
P
T
E
V
A
Y
S
T
A
Site 38
Y332
S
Y
P
T
E
V
A
Y
S
T
A
D
I
F
D
Site 39
S352
D
F
R
W
K
D
A
S
G
P
K
E
K
L
E
Site 40
Y361
P
K
E
K
L
E
I
Y
K
P
T
A
R
Y
C
Site 41
Y367
I
Y
K
P
T
A
R
Y
C
I
R
S
M
L
S
Site 42
S371
T
A
R
Y
C
I
R
S
M
L
S
L
E
S
T
Site 43
T402
T
R
G
K
G
A
G
T
P
N
L
I
S
T
E
Site 44
S411
N
L
I
S
T
E
F
S
A
E
L
H
Y
K
V
Site 45
Y416
E
F
S
A
E
L
H
Y
K
V
D
V
L
P
W
Site 46
Y433
C
K
G
D
W
S
R
Y
N
E
A
R
P
P
N
Site 47
T446
P
N
N
G
Q
K
C
T
E
S
P
S
D
E
D
Site 48
S448
N
G
Q
K
C
T
E
S
P
S
D
E
D
Y
I
Site 49
S450
Q
K
C
T
E
S
P
S
D
E
D
Y
I
K
Q
Site 50
Y454
E
S
P
S
D
E
D
Y
I
K
Q
F
Q
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation