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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGPS
Full Name:
Alkyldihydroxyacetonephosphate synthase, peroxisomal
Alias:
ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; Alkyl-DHAP synthase; Alkylglycerone phosphate synthase; EC 2.5.1.26
Type:
Lipid Metabolism - ether lipid; EC 2.5.1.26; Oxidoreductase; Mitochondrial; Transferase
Mass (Da):
72912
Number AA:
658
UniProt ID:
O00116
International Prot ID:
IPI00010349
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005778
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0008609
GO:0016491
PhosphoSite+
KinaseNET
Biological Process:
GO:0008610
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
T
G
L
G
A
G
A
S
Y
G
S
A
A
D
R
Site 2
S42
G
R
R
L
R
V
L
S
G
H
L
L
G
R
P
Site 3
S54
G
R
P
R
E
A
L
S
T
N
E
C
K
A
R
Site 4
T55
R
P
R
E
A
L
S
T
N
E
C
K
A
R
R
Site 5
S65
C
K
A
R
R
A
A
S
A
A
T
A
A
P
T
Site 6
T68
R
R
A
A
S
A
A
T
A
A
P
T
A
T
P
Site 7
T72
S
A
A
T
A
A
P
T
A
T
P
A
A
Q
E
Site 8
T74
A
T
A
A
P
T
A
T
P
A
A
Q
E
S
G
Site 9
T114
K
K
G
Q
I
E
L
T
G
K
R
Y
P
L
S
Site 10
Y118
I
E
L
T
G
K
R
Y
P
L
S
G
M
G
L
Site 11
S121
T
G
K
R
Y
P
L
S
G
M
G
L
P
T
F
Site 12
T127
L
S
G
M
G
L
P
T
F
K
E
W
I
Q
N
Site 13
T144
G
V
N
V
E
H
K
T
T
S
K
A
S
L
N
Site 14
T145
V
N
V
E
H
K
T
T
S
K
A
S
L
N
P
Site 15
S149
H
K
T
T
S
K
A
S
L
N
P
S
D
T
P
Site 16
S153
S
K
A
S
L
N
P
S
D
T
P
P
S
V
V
Site 17
T155
A
S
L
N
P
S
D
T
P
P
S
V
V
N
E
Site 18
S158
N
P
S
D
T
P
P
S
V
V
N
E
D
F
L
Site 19
S174
D
L
K
E
T
N
I
S
Y
S
Q
E
A
D
D
Site 20
S176
K
E
T
N
I
S
Y
S
Q
E
A
D
D
R
V
Site 21
S257
D
E
T
R
T
I
I
S
L
D
T
S
Q
M
N
Site 22
S294
L
E
R
Q
L
K
E
S
G
Y
C
T
G
H
E
Site 23
Y296
R
Q
L
K
E
S
G
Y
C
T
G
H
E
P
D
Site 24
T298
L
K
E
S
G
Y
C
T
G
H
E
P
D
S
L
Site 25
S304
C
T
G
H
E
P
D
S
L
E
F
S
T
V
G
Site 26
S308
E
P
D
S
L
E
F
S
T
V
G
G
W
V
S
Site 27
T309
P
D
S
L
E
F
S
T
V
G
G
W
V
S
T
Site 28
S315
S
T
V
G
G
W
V
S
T
R
A
S
G
M
K
Site 29
Y326
S
G
M
K
K
N
I
Y
G
N
I
E
D
L
V
Site 30
S348
P
R
G
I
I
E
K
S
C
Q
G
P
R
M
S
Site 31
S355
S
C
Q
G
P
R
M
S
T
G
P
D
I
H
H
Site 32
T356
C
Q
G
P
R
M
S
T
G
P
D
I
H
H
F
Site 33
Y387
K
I
R
P
V
P
E
Y
Q
K
Y
G
S
V
A
Site 34
Y390
P
V
P
E
Y
Q
K
Y
G
S
V
A
F
P
N
Site 35
S417
K
Q
R
C
A
P
A
S
I
R
L
M
D
N
K
Site 36
Y451
L
D
G
L
K
K
F
Y
I
T
K
F
K
G
F
Site 37
Y485
L
Q
H
E
K
Q
V
Y
D
I
A
A
K
F
G
Site 38
Y505
E
D
N
G
Q
R
G
Y
L
L
T
Y
V
I
A
Site 39
Y509
Q
R
G
Y
L
L
T
Y
V
I
A
Y
I
R
D
Site 40
Y513
L
L
T
Y
V
I
A
Y
I
R
D
L
A
L
E
Site 41
Y522
R
D
L
A
L
E
Y
Y
V
L
G
E
S
F
E
Site 42
S527
E
Y
Y
V
L
G
E
S
F
E
T
S
A
P
W
Site 43
T530
V
L
G
E
S
F
E
T
S
A
P
W
D
R
V
Site 44
S531
L
G
E
S
F
E
T
S
A
P
W
D
R
V
V
Site 45
T549
R
N
V
K
E
R
I
T
R
E
C
K
E
K
G
Site 46
T564
V
Q
F
A
P
F
S
T
C
R
V
T
Q
T
Y
Site 47
T568
P
F
S
T
C
R
V
T
Q
T
Y
D
A
G
A
Site 48
Y585
Y
F
Y
F
A
F
N
Y
R
G
I
S
D
P
L
Site 49
S589
A
F
N
Y
R
G
I
S
D
P
L
T
V
F
E
Site 50
T593
R
G
I
S
D
P
L
T
V
F
E
Q
T
E
A
Site 51
S612
E
I
L
A
N
G
G
S
L
S
H
H
H
G
V
Site 52
S614
L
A
N
G
G
S
L
S
H
H
H
G
V
G
K
Site 53
S630
R
K
Q
W
L
K
E
S
I
S
D
V
G
F
G
Site 54
Y645
M
L
K
S
V
K
E
Y
V
D
P
N
N
I
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation