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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYO1F
Full Name:
Myosin-If
Alias:
Myosin If; Myosin-ID; Myosin-IE
Type:
Motor protein
Mass (Da):
124844
Number AA:
1098
UniProt ID:
O00160
International Prot ID:
IPI00218638
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016461
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003779
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y45
R
K
R
F
M
D
D
Y
I
F
T
Y
I
G
S
Site 2
Y65
N
P
F
K
Q
M
P
Y
F
T
D
R
E
I
D
Site 3
Y74
T
D
R
E
I
D
L
Y
Q
G
A
A
Q
Y
E
Site 4
Y80
L
Y
Q
G
A
A
Q
Y
E
N
P
P
H
I
Y
Site 5
Y94
Y
A
L
T
D
N
M
Y
R
N
M
L
I
D
C
Site 6
S109
E
N
Q
C
V
I
I
S
G
E
S
G
A
G
K
Site 7
T117
G
E
S
G
A
G
K
T
V
A
A
K
Y
I
M
Site 8
Y122
G
K
T
V
A
A
K
Y
I
M
G
Y
I
S
K
Site 9
S128
K
Y
I
M
G
Y
I
S
K
V
S
G
G
G
E
Site 10
S131
M
G
Y
I
S
K
V
S
G
G
G
E
K
V
Q
Site 11
T159
E
A
F
G
N
A
K
T
V
R
N
N
N
S
S
Site 12
S165
K
T
V
R
N
N
N
S
S
R
F
G
K
Y
F
Site 13
S166
T
V
R
N
N
N
S
S
R
F
G
K
Y
F
E
Site 14
Y171
N
S
S
R
F
G
K
Y
F
E
I
Q
F
S
R
Site 15
S177
K
Y
F
E
I
Q
F
S
R
G
G
E
P
D
G
Site 16
S188
E
P
D
G
G
K
I
S
N
F
L
L
E
K
S
Site 17
S195
S
N
F
L
L
E
K
S
R
V
V
M
Q
N
E
Site 18
Y210
N
E
R
N
F
H
I
Y
Y
Q
L
L
E
G
A
Site 19
Y211
E
R
N
F
H
I
Y
Y
Q
L
L
E
G
A
S
Site 20
S218
Y
Q
L
L
E
G
A
S
Q
E
Q
R
Q
N
L
Site 21
T229
R
Q
N
L
G
L
M
T
P
D
Y
Y
Y
Y
L
Site 22
Y232
L
G
L
M
T
P
D
Y
Y
Y
Y
L
N
Q
S
Site 23
Y233
G
L
M
T
P
D
Y
Y
Y
Y
L
N
Q
S
D
Site 24
Y234
L
M
T
P
D
Y
Y
Y
Y
L
N
Q
S
D
T
Site 25
Y235
M
T
P
D
Y
Y
Y
Y
L
N
Q
S
D
T
Y
Site 26
T241
Y
Y
L
N
Q
S
D
T
Y
Q
V
D
G
T
D
Site 27
Y242
Y
L
N
Q
S
D
T
Y
Q
V
D
G
T
D
D
Site 28
T247
D
T
Y
Q
V
D
G
T
D
D
R
S
D
F
G
Site 29
S251
V
D
G
T
D
D
R
S
D
F
G
E
T
L
S
Site 30
Y294
S
F
C
E
D
G
N
Y
A
R
V
E
S
V
D
Site 31
S314
A
Y
L
L
G
I
D
S
G
R
L
Q
E
K
L
Site 32
T322
G
R
L
Q
E
K
L
T
S
R
K
M
D
S
R
Site 33
S323
R
L
Q
E
K
L
T
S
R
K
M
D
S
R
W
Site 34
S334
D
S
R
W
G
G
R
S
E
S
I
N
V
T
L
Site 35
S336
R
W
G
G
R
S
E
S
I
N
V
T
L
N
V
Site 36
T340
R
S
E
S
I
N
V
T
L
N
V
E
Q
A
A
Site 37
Y348
L
N
V
E
Q
A
A
Y
T
R
D
A
L
A
K
Site 38
Y426
L
K
A
E
Q
E
E
Y
V
Q
E
G
I
R
W
Site 39
Y438
I
R
W
T
P
I
Q
Y
F
N
N
K
V
V
C
Site 40
T478
T
G
G
G
A
D
Q
T
L
L
Q
K
L
Q
A
Site 41
Y505
A
G
F
V
I
H
H
Y
A
G
K
V
S
Y
D
Site 42
Y511
H
Y
A
G
K
V
S
Y
D
V
S
G
F
C
E
Site 43
S514
G
K
V
S
Y
D
V
S
G
F
C
E
R
N
R
Site 44
S526
R
N
R
D
V
L
F
S
D
L
I
E
L
M
Q
Site 45
T534
D
L
I
E
L
M
Q
T
S
E
Q
A
F
L
R
Site 46
S535
L
I
E
L
M
Q
T
S
E
Q
A
F
L
R
M
Site 47
S557
G
D
K
K
G
R
P
S
T
A
G
S
K
I
K
Site 48
T558
D
K
K
G
R
P
S
T
A
G
S
K
I
K
K
Site 49
S561
G
R
P
S
T
A
G
S
K
I
K
K
Q
A
N
Site 50
Y581
L
M
R
C
T
P
H
Y
I
R
C
I
K
P
N
Site 51
Y607
R
V
K
H
Q
V
E
Y
L
G
L
K
E
N
I
Site 52
Y623
V
R
R
A
G
F
A
Y
R
R
Q
F
A
K
F
Site 53
T638
L
Q
R
Y
A
I
L
T
P
E
T
W
P
R
W
Site 54
Y667
V
N
M
E
P
D
Q
Y
Q
M
G
S
T
K
V
Site 55
Y713
R
H
V
A
V
R
K
Y
E
E
M
R
E
E
A
Site 56
S734
K
K
E
R
R
R
N
S
I
N
R
N
F
V
G
Site 57
Y743
N
R
N
F
V
G
D
Y
L
G
L
E
E
R
P
Site 58
S767
E
R
V
D
F
A
D
S
V
T
K
Y
D
R
R
Site 59
Y771
F
A
D
S
V
T
K
Y
D
R
R
F
K
P
I
Site 60
Y790
I
L
T
P
K
C
V
Y
V
I
G
R
E
K
M
Site 61
S823
I
Q
A
L
R
G
V
S
L
S
T
R
Q
D
D
Site 62
S825
A
L
R
G
V
S
L
S
T
R
Q
D
D
F
F
Site 63
S841
L
Q
E
D
A
A
D
S
F
L
E
S
V
F
K
Site 64
T863
C
K
R
F
E
E
A
T
R
R
P
L
P
L
T
Site 65
T870
T
R
R
P
L
P
L
T
F
S
D
T
L
Q
F
Site 66
S872
R
P
L
P
L
T
F
S
D
T
L
Q
F
R
V
Site 67
T874
L
P
L
T
F
S
D
T
L
Q
F
R
V
K
K
Site 68
T889
E
G
W
G
G
G
G
T
R
S
V
T
F
S
R
Site 69
S891
W
G
G
G
G
T
R
S
V
T
F
S
R
G
F
Site 70
T893
G
G
G
T
R
S
V
T
F
S
R
G
F
G
D
Site 71
S895
G
T
R
S
V
T
F
S
R
G
F
G
D
L
A
Site 72
T910
V
L
K
V
G
G
R
T
L
T
V
S
V
G
D
Site 73
T912
K
V
G
G
R
T
L
T
V
S
V
G
D
G
L
Site 74
S914
G
G
R
T
L
T
V
S
V
G
D
G
L
P
K
Site 75
S922
V
G
D
G
L
P
K
S
S
K
P
T
R
K
G
Site 76
S938
A
K
G
K
P
R
R
S
S
Q
A
P
T
R
A
Site 77
S939
K
G
K
P
R
R
S
S
Q
A
P
T
R
A
A
Site 78
T943
R
R
S
S
Q
A
P
T
R
A
A
P
A
P
P
Site 79
S961
D
R
N
G
V
P
P
S
A
R
G
G
P
L
P
Site 80
S973
P
L
P
L
E
I
M
S
G
G
G
T
H
R
P
Site 81
T977
E
I
M
S
G
G
G
T
H
R
P
P
R
G
P
Site 82
S986
R
P
P
R
G
P
P
S
T
S
L
G
A
S
R
Site 83
T987
P
P
R
G
P
P
S
T
S
L
G
A
S
R
R
Site 84
S988
P
R
G
P
P
S
T
S
L
G
A
S
R
R
P
Site 85
S992
P
S
T
S
L
G
A
S
R
R
P
R
A
R
P
Site 86
S1001
R
P
R
A
R
P
P
S
E
H
N
T
E
F
L
Site 87
T1005
R
P
P
S
E
H
N
T
E
F
L
N
V
P
D
Site 88
S1023
A
G
M
Q
R
K
R
S
V
G
Q
R
P
V
P
Site 89
T1041
R
P
K
P
Q
P
R
T
H
G
P
R
C
R
A
Site 90
Y1050
G
P
R
C
R
A
L
Y
Q
Y
V
G
Q
D
V
Site 91
Y1052
R
C
R
A
L
Y
Q
Y
V
G
Q
D
V
D
E
Site 92
S1061
G
Q
D
V
D
E
L
S
F
N
V
N
E
V
I
Site 93
Y1094
E
G
L
F
P
G
N
Y
V
E
K
I
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation