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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AP4M1
Full Name:
AP-4 complex subunit mu-1
Alias:
Adapter-related protein complex 3 mu-1 subunit; Adapter-related protein complex 4 mu-1 subunit, AP-4 adapter complex mu subunit, Mu subunit of AP-4, Mu4-adaptin , Mu-adaptin-related protein 2; AP-3 adapter complex mu3A subunit; AP-3 complex subunit mu-1; Mu-adaptin 3A
Type:
Uncharacterized protein
Mass (Da):
49977
Number AA:
453
UniProt ID:
O00189
International Prot ID:
IPI00103040
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000138
GO:0030131
GO:0005905
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005215
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
S
K
G
D
P
L
I
Y
K
D
F
R
G
D
S
Site 2
S24
Y
K
D
F
R
G
D
S
G
G
R
D
V
A
E
Site 3
Y34
R
D
V
A
E
L
F
Y
R
K
L
T
G
L
P
Site 4
T38
E
L
F
Y
R
K
L
T
G
L
P
G
D
E
S
Site 5
S45
T
G
L
P
G
D
E
S
P
V
V
M
H
H
H
Site 6
Y65
H
I
R
H
S
G
L
Y
L
V
V
T
T
S
E
Site 7
S78
S
E
N
V
S
P
F
S
L
L
E
L
L
S
R
Site 8
Y119
L
L
D
E
V
L
D
Y
G
Y
V
Q
T
T
S
Site 9
Y121
D
E
V
L
D
Y
G
Y
V
Q
T
T
S
T
E
Site 10
T136
M
L
R
N
F
I
Q
T
E
A
V
V
S
K
P
Site 11
S145
A
V
V
S
K
P
F
S
L
F
D
L
S
S
V
Site 12
S150
P
F
S
L
F
D
L
S
S
V
G
L
F
G
A
Site 13
T159
V
G
L
F
G
A
E
T
Q
Q
S
K
V
A
P
Site 14
S162
F
G
A
E
T
Q
Q
S
K
V
A
P
S
S
A
Site 15
S167
Q
Q
S
K
V
A
P
S
S
A
A
S
R
P
V
Site 16
S168
Q
S
K
V
A
P
S
S
A
A
S
R
P
V
L
Site 17
S171
V
A
P
S
S
A
A
S
R
P
V
L
S
S
R
Site 18
S176
A
A
S
R
P
V
L
S
S
R
S
D
Q
S
Q
Site 19
S177
A
S
R
P
V
L
S
S
R
S
D
Q
S
Q
K
Site 20
S182
L
S
S
R
S
D
Q
S
Q
K
N
E
V
F
L
Site 21
S218
Q
G
E
I
R
L
K
S
F
L
P
S
G
S
E
Site 22
S222
R
L
K
S
F
L
P
S
G
S
E
M
R
I
G
Site 23
S224
K
S
F
L
P
S
G
S
E
M
R
I
G
L
T
Site 24
S239
E
E
F
C
V
G
K
S
E
L
R
G
Y
G
P
Site 25
Y244
G
K
S
E
L
R
G
Y
G
P
G
I
R
V
D
Site 26
S254
G
I
R
V
D
E
V
S
F
H
S
S
V
N
L
Site 27
S258
D
E
V
S
F
H
S
S
V
N
L
D
E
F
E
Site 28
S266
V
N
L
D
E
F
E
S
H
R
I
L
R
L
Q
Site 29
T280
Q
P
P
Q
G
E
L
T
V
M
R
Y
Q
L
S
Site 30
S287
T
V
M
R
Y
Q
L
S
D
D
L
P
S
P
L
Site 31
S292
Q
L
S
D
D
L
P
S
P
L
P
F
R
L
F
Site 32
S301
L
P
F
R
L
F
P
S
V
Q
W
D
R
G
S
Site 33
S308
S
V
Q
W
D
R
G
S
G
R
L
Q
V
Y
L
Site 34
Y314
G
S
G
R
L
Q
V
Y
L
K
L
R
C
D
L
Site 35
S323
K
L
R
C
D
L
L
S
K
S
Q
A
L
N
V
Site 36
S325
R
C
D
L
L
S
K
S
Q
A
L
N
V
R
L
Site 37
S342
P
L
P
R
G
V
V
S
L
S
Q
E
L
S
S
Site 38
S344
P
R
G
V
V
S
L
S
Q
E
L
S
S
P
E
Site 39
S348
V
S
L
S
Q
E
L
S
S
P
E
Q
K
A
E
Site 40
S349
S
L
S
Q
E
L
S
S
P
E
Q
K
A
E
L
Site 41
S372
L
P
R
V
Q
G
G
S
Q
L
S
G
L
F
Q
Site 42
S390
P
G
P
P
G
P
P
S
H
G
L
S
T
S
A
Site 43
S394
G
P
P
S
H
G
L
S
T
S
A
S
P
L
G
Site 44
S396
P
S
H
G
L
S
T
S
A
S
P
L
G
L
G
Site 45
S408
G
L
G
P
A
S
L
S
F
E
L
P
R
H
T
Site 46
T415
S
F
E
L
P
R
H
T
C
S
G
L
Q
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation