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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMD11
Full Name:
26S proteasome non-ATPase regulatory subunit 11
Alias:
26S proteasome regulatory subunit p44.5; 26S proteasome regulatory subunit S9; MGC3844; P44.5; Proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; PSD11; Rpn6; S9
Type:
Proteasome complex; Protease
Mass (Da):
47464
Number AA:
422
UniProt ID:
O00231
International Prot ID:
IPI00105598
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000502
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031145
GO:0051436
GO:0051437
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
V
E
F
Q
R
A
Q
S
L
L
S
T
D
R
E
Site 2
S17
Q
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
Site 3
T18
R
A
Q
S
L
L
S
T
D
R
E
A
S
I
D
Site 4
S23
L
S
T
D
R
E
A
S
I
D
I
L
H
S
I
Site 5
Y72
E
L
G
G
L
L
K
Y
V
R
P
F
L
N
S
Site 6
S79
Y
V
R
P
F
L
N
S
I
S
K
A
K
A
A
Site 7
S81
R
P
F
L
N
S
I
S
K
A
K
A
A
R
L
Site 8
S119
E
C
I
E
W
A
K
S
E
K
R
T
F
L
R
Site 9
T123
W
A
K
S
E
K
R
T
F
L
R
Q
A
L
E
Site 10
S135
A
L
E
A
R
L
V
S
L
Y
F
D
T
K
R
Site 11
Y137
E
A
R
L
V
S
L
Y
F
D
T
K
R
Y
Q
Site 12
T140
L
V
S
L
Y
F
D
T
K
R
Y
Q
E
A
L
Site 13
T176
V
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
Site 14
Y177
Q
L
L
E
S
K
T
Y
H
A
L
S
N
L
P
Site 15
S181
S
K
T
Y
H
A
L
S
N
L
P
K
A
R
A
Site 16
T191
P
K
A
R
A
A
L
T
S
A
R
T
T
A
N
Site 17
S192
K
A
R
A
A
L
T
S
A
R
T
T
A
N
A
Site 18
Y201
R
T
T
A
N
A
I
Y
C
P
P
K
L
Q
A
Site 19
T209
C
P
P
K
L
Q
A
T
L
D
M
Q
S
G
I
Site 20
Y229
E
K
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
Site 21
Y231
D
W
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Site 22
Y233
K
T
A
Y
S
Y
F
Y
E
A
F
E
G
Y
D
Site 23
Y239
F
Y
E
A
F
E
G
Y
D
S
I
D
S
P
K
Site 24
S241
E
A
F
E
G
Y
D
S
I
D
S
P
K
A
I
Site 25
S244
E
G
Y
D
S
I
D
S
P
K
A
I
T
S
L
Site 26
S272
E
D
V
Q
A
L
V
S
G
K
L
A
L
R
Y
Site 27
Y279
S
G
K
L
A
L
R
Y
A
G
R
Q
T
E
A
Site 28
T284
L
R
Y
A
G
R
Q
T
E
A
L
K
C
V
A
Site 29
S294
L
K
C
V
A
Q
A
S
K
N
R
S
L
A
D
Site 30
S298
A
Q
A
S
K
N
R
S
L
A
D
F
E
K
A
Site 31
T307
A
D
F
E
K
A
L
T
D
Y
R
A
E
L
R
Site 32
Y309
F
E
K
A
L
T
D
Y
R
A
E
L
R
D
D
Site 33
T321
R
D
D
P
I
I
S
T
H
L
A
K
L
Y
D
Site 34
Y327
S
T
H
L
A
K
L
Y
D
N
L
L
E
Q
N
Site 35
S357
I
S
S
L
I
K
L
S
K
A
D
V
E
R
K
Site 36
S366
A
D
V
E
R
K
L
S
Q
M
I
L
D
K
K
Site 37
T396
D
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
Site 38
Y397
E
P
P
V
D
K
T
Y
E
A
A
L
E
T
I
Site 39
Y415
S
K
V
V
D
S
L
Y
N
K
A
K
K
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation