KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TULP1
Full Name:
Tubby-related protein 1
Alias:
RP14; tubby like protein 1; tubby-like 1; tubby-related 1; TUBL1
Type:
Cytoskeletal protein
Mass (Da):
60650
Number AA:
UniProt ID:
O00294
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007601
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
P
L
R
D
E
T
L
R
E
V
W
A
S
Site 2
S14
T
L
R
E
V
W
A
S
D
S
G
H
E
E
E
Site 3
S16
R
E
V
W
A
S
D
S
G
H
E
E
E
S
L
Site 4
S22
D
S
G
H
E
E
E
S
L
S
P
E
A
P
R
Site 5
S24
G
H
E
E
E
S
L
S
P
E
A
P
R
R
P
Site 6
T46
Q
R
L
R
K
K
R
T
E
A
P
E
S
P
C
Site 7
S51
K
R
T
E
A
P
E
S
P
C
P
T
G
S
K
Site 8
T55
A
P
E
S
P
C
P
T
G
S
K
P
R
K
P
Site 9
S57
E
S
P
C
P
T
G
S
K
P
R
K
P
G
A
Site 10
T67
R
K
P
G
A
G
R
T
G
R
P
R
E
E
P
Site 11
S75
G
R
P
R
E
E
P
S
P
D
P
A
Q
A
R
Site 12
T86
A
Q
A
R
A
P
Q
T
V
Y
A
R
F
L
R
Site 13
Y88
A
R
A
P
Q
T
V
Y
A
R
F
L
R
D
P
Site 14
T105
K
K
R
D
P
R
E
T
F
L
V
A
R
A
P
Site 15
S151
K
K
P
L
R
E
K
S
S
A
D
L
K
E
R
Site 16
S152
K
P
L
R
E
K
S
S
A
D
L
K
E
R
R
Site 17
S171
G
P
R
G
D
L
G
S
P
D
P
P
P
K
P
Site 18
T197
E
G
T
K
M
R
K
T
K
K
K
G
S
G
E
Site 19
S210
G
E
A
D
K
D
P
S
G
S
P
A
S
A
R
Site 20
S212
A
D
K
D
P
S
G
S
P
A
S
A
R
K
S
Site 21
S215
D
P
S
G
S
P
A
S
A
R
K
S
P
A
A
Site 22
S230
M
F
L
V
G
E
G
S
P
D
K
K
A
L
K
Site 23
T241
K
A
L
K
K
K
G
T
P
K
G
A
R
K
E
Site 24
T257
E
E
E
E
E
A
A
T
V
I
K
K
S
N
Q
Site 25
S262
A
A
T
V
I
K
K
S
N
Q
K
G
K
A
K
Site 26
S283
A
K
E
E
R
A
P
S
P
P
V
E
V
D
E
Site 27
T304
R
P
A
P
Q
G
R
T
V
R
C
R
L
T
R
Site 28
T310
R
T
V
R
C
R
L
T
R
D
K
K
G
M
D
Site 29
Y321
K
G
M
D
R
G
M
Y
P
S
Y
F
L
H
L
Site 30
Y324
D
R
G
M
Y
P
S
Y
F
L
H
L
D
T
E
Site 31
S345
A
G
R
K
R
K
R
S
K
T
A
N
Y
L
I
Site 32
T347
R
K
R
K
R
S
K
T
A
N
Y
L
I
S
I
Site 33
Y350
K
R
S
K
T
A
N
Y
L
I
S
I
D
P
T
Site 34
T357
Y
L
I
S
I
D
P
T
N
L
S
R
G
G
E
Site 35
S372
N
F
I
G
K
L
R
S
N
L
L
G
N
R
F
Site 36
T380
N
L
L
G
N
R
F
T
V
F
D
N
G
Q
N
Site 37
Y392
G
Q
N
P
Q
R
G
Y
S
T
N
V
A
S
L
Site 38
S393
Q
N
P
Q
R
G
Y
S
T
N
V
A
S
L
R
Site 39
T394
N
P
Q
R
G
Y
S
T
N
V
A
S
L
R
Q
Site 40
S398
G
Y
S
T
N
V
A
S
L
R
Q
E
L
A
A
Site 41
T422
F
R
G
P
R
R
M
T
V
I
I
P
G
M
S
Site 42
S443
P
I
R
P
R
N
A
S
D
G
L
L
V
R
W
Site 43
T454
L
V
R
W
Q
N
K
T
L
E
S
L
I
E
L
Site 44
S472
P
P
V
W
N
D
D
S
G
S
Y
T
L
N
F
Site 45
T476
N
D
D
S
G
S
Y
T
L
N
F
Q
G
R
V
Site 46
T484
L
N
F
Q
G
R
V
T
Q
A
S
V
K
N
F
Site 47
S487
Q
G
R
V
T
Q
A
S
V
K
N
F
Q
I
V
Site 48
Y501
V
H
A
D
D
P
D
Y
I
V
L
Q
F
G
R
Site 49
T515
R
V
A
E
D
A
F
T
L
D
Y
R
Y
P
L
Site 50
Y518
E
D
A
F
T
L
D
Y
R
Y
P
L
C
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation