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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXE1
Full Name:
Forkhead box protein E1
Alias:
Forkhead box protein E2;Forkhead-related protein FKHL15;HFKH4;HNF-3/fork head-like protein 5;Thyroid transcription factor 2
Type:
Mass (Da):
38076
Number AA:
373
UniProt ID:
O00358
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
A
E
S
G
P
P
P
Site 2
S5
_
_
_
M
T
A
E
S
G
P
P
P
P
Q
P
Site 3
T17
P
Q
P
E
V
L
A
T
V
K
E
E
R
G
E
Site 4
T25
V
K
E
E
R
G
E
T
A
A
G
A
G
V
P
Site 5
T36
A
G
V
P
G
E
A
T
G
R
G
A
G
G
R
Site 6
Y56
L
Q
R
G
K
P
P
Y
S
Y
I
A
L
I
A
Site 7
S57
Q
R
G
K
P
P
Y
S
Y
I
A
L
I
A
M
Site 8
T75
H
A
P
E
R
R
L
T
L
G
G
I
Y
K
F
Site 9
T84
G
G
I
Y
K
F
I
T
E
R
F
P
F
Y
R
Site 10
Y90
I
T
E
R
F
P
F
Y
R
D
N
P
K
K
W
Site 11
T106
N
S
I
R
H
N
L
T
L
N
D
C
F
L
K
Site 12
Y126
G
R
P
G
K
G
N
Y
W
A
L
D
P
N
A
Site 13
S141
E
D
M
F
E
S
G
S
F
L
R
R
R
K
R
Site 14
S152
R
R
K
R
F
K
R
S
D
L
S
T
Y
P
A
Site 15
S155
R
F
K
R
S
D
L
S
T
Y
P
A
Y
M
H
Site 16
T156
F
K
R
S
D
L
S
T
Y
P
A
Y
M
H
D
Site 17
Y157
K
R
S
D
L
S
T
Y
P
A
Y
M
H
D
A
Site 18
Y160
D
L
S
T
Y
P
A
Y
M
H
D
A
A
A
A
Site 19
Y197
P
P
Y
P
G
A
V
Y
A
G
Y
A
P
P
S
Site 20
Y213
A
A
P
P
P
V
Y
Y
P
A
A
S
P
G
P
Site 21
S233
L
V
P
E
R
P
L
S
P
E
L
G
P
A
P
Site 22
S241
P
E
L
G
P
A
P
S
G
P
G
G
S
C
A
Site 23
Y261
A
P
A
T
T
T
G
Y
Q
P
A
G
C
T
G
Site 24
S275
G
A
R
P
A
N
P
S
A
Y
A
A
A
Y
A
Site 25
Y281
P
S
A
Y
A
A
A
Y
A
G
P
D
G
A
Y
Site 26
Y288
Y
A
G
P
D
G
A
Y
P
Q
G
A
G
S
A
Site 27
S308
G
R
L
A
G
P
A
S
P
P
A
G
G
S
S
Site 28
T321
S
S
G
G
V
E
T
T
V
D
F
Y
G
R
T
Site 29
Y325
V
E
T
T
V
D
F
Y
G
R
T
S
P
G
Q
Site 30
S329
V
D
F
Y
G
R
T
S
P
G
Q
F
G
A
L
Site 31
S350
G
G
Q
L
G
G
A
S
A
G
A
Y
H
A
R
Site 32
Y354
G
G
A
S
A
G
A
Y
H
A
R
H
A
A
A
Site 33
Y362
H
A
R
H
A
A
A
Y
P
G
G
I
D
R
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation