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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EML1
Full Name:
Echinoderm microtubule-associated protein-like 1
Alias:
Echinoderm microtubule associated protein like 1; Echinoderm microtubule-associated protein-like; ELP79; EMAL1; EMAP; EMAPL; FLJ45033; HuEMAP; HuEMAP-1
Type:
Microtubule binding protein; Cytoskeletal protein
Mass (Da):
89861
Number AA:
815
UniProt ID:
O00423
International Prot ID:
IPI00004582
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
GO:0005875
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
D
G
F
S
S
Y
S
S
L
Y
D
T
Site 2
S10
D
G
F
S
S
Y
S
S
L
Y
D
T
S
S
L
Site 3
Y12
F
S
S
Y
S
S
L
Y
D
T
S
S
L
L
Q
Site 4
T14
S
Y
S
S
L
Y
D
T
S
S
L
L
Q
F
C
Site 5
S15
Y
S
S
L
Y
D
T
S
S
L
L
Q
F
C
N
Site 6
S16
S
S
L
Y
D
T
S
S
L
L
Q
F
C
N
D
Site 7
S25
L
Q
F
C
N
D
D
S
A
S
A
A
S
S
M
Site 8
S27
F
C
N
D
D
S
A
S
A
A
S
S
M
E
V
Site 9
S31
D
S
A
S
A
A
S
S
M
E
V
T
D
R
I
Site 10
T35
A
A
S
S
M
E
V
T
D
R
I
A
S
L
E
Site 11
S40
E
V
T
D
R
I
A
S
L
E
Q
R
V
Q
M
Site 12
T69
V
V
R
R
L
N
I
T
E
E
Q
Q
A
V
L
Site 13
T90
K
A
R
P
L
M
Q
T
L
P
L
R
T
T
V
Site 14
T96
Q
T
L
P
L
R
T
T
V
N
N
G
T
V
L
Site 15
T101
R
T
T
V
N
N
G
T
V
L
P
K
K
P
T
Site 16
S110
L
P
K
K
P
T
G
S
L
P
S
P
S
G
V
Site 17
S113
K
P
T
G
S
L
P
S
P
S
G
V
R
K
E
Site 18
S115
T
G
S
L
P
S
P
S
G
V
R
K
E
T
A
Site 19
T121
P
S
G
V
R
K
E
T
A
V
P
A
T
K
S
Site 20
S128
T
A
V
P
A
T
K
S
N
I
K
R
T
S
S
Site 21
T133
T
K
S
N
I
K
R
T
S
S
S
E
R
V
S
Site 22
S134
K
S
N
I
K
R
T
S
S
S
E
R
V
S
P
Site 23
S135
S
N
I
K
R
T
S
S
S
E
R
V
S
P
G
Site 24
S136
N
I
K
R
T
S
S
S
E
R
V
S
P
G
G
Site 25
S140
T
S
S
S
E
R
V
S
P
G
G
R
R
E
S
Site 26
S147
S
P
G
G
R
R
E
S
N
G
D
S
R
G
N
Site 27
S151
R
R
E
S
N
G
D
S
R
G
N
R
N
R
T
Site 28
T158
S
R
G
N
R
N
R
T
G
S
T
S
S
S
S
Site 29
S160
G
N
R
N
R
T
G
S
T
S
S
S
S
S
G
Site 30
T161
N
R
N
R
T
G
S
T
S
S
S
S
S
G
K
Site 31
S162
R
N
R
T
G
S
T
S
S
S
S
S
G
K
K
Site 32
S164
R
T
G
S
T
S
S
S
S
S
G
K
K
N
S
Site 33
S165
T
G
S
T
S
S
S
S
S
G
K
K
N
S
E
Site 34
S166
G
S
T
S
S
S
S
S
G
K
K
N
S
E
S
Site 35
S171
S
S
S
G
K
K
N
S
E
S
K
P
K
E
P
Site 36
S173
S
G
K
K
N
S
E
S
K
P
K
E
P
V
F
Site 37
S181
K
P
K
E
P
V
F
S
A
E
E
G
Y
V
K
Site 38
Y186
V
F
S
A
E
E
G
Y
V
K
L
F
L
R
G
Site 39
T197
F
L
R
G
R
P
V
T
M
Y
M
P
K
D
Q
Site 40
Y199
R
G
R
P
V
T
M
Y
M
P
K
D
Q
V
D
Site 41
S207
M
P
K
D
Q
V
D
S
Y
S
L
E
A
K
V
Site 42
Y208
P
K
D
Q
V
D
S
Y
S
L
E
A
K
V
E
Site 43
S209
K
D
Q
V
D
S
Y
S
L
E
A
K
V
E
L
Site 44
Y227
R
L
K
L
E
W
V
Y
G
Y
R
G
R
D
C
Site 45
Y239
R
D
C
R
N
N
L
Y
L
L
P
T
G
E
T
Site 46
Y267
E
E
Q
L
Q
R
H
Y
A
G
H
N
D
D
V
Site 47
T288
P
D
R
I
T
I
A
T
G
Q
V
A
G
T
S
Site 48
S295
T
G
Q
V
A
G
T
S
K
D
G
K
Q
L
P
Site 49
T389
T
D
T
N
I
I
V
T
C
G
K
S
H
L
Y
Site 50
Y396
T
C
G
K
S
H
L
Y
F
W
T
L
E
G
S
Site 51
T399
K
S
H
L
Y
F
W
T
L
E
G
S
S
L
N
Site 52
T432
T
F
S
E
N
G
D
T
I
T
G
D
S
S
G
Site 53
T434
S
E
N
G
D
T
I
T
G
D
S
S
G
N
I
Site 54
T448
I
L
V
W
G
K
G
T
N
R
I
S
Y
A
V
Site 55
S452
G
K
G
T
N
R
I
S
Y
A
V
Q
G
A
H
Site 56
Y453
K
G
T
N
R
I
S
Y
A
V
Q
G
A
H
E
Site 57
S476
L
R
D
G
T
L
V
S
G
G
G
K
D
R
K
Site 58
S486
G
K
D
R
K
L
I
S
W
S
G
N
Y
Q
K
Site 59
S488
D
R
K
L
I
S
W
S
G
N
Y
Q
K
L
R
Site 60
Y491
L
I
S
W
S
G
N
Y
Q
K
L
R
K
T
E
Site 61
T497
N
Y
Q
K
L
R
K
T
E
I
P
E
Q
F
G
Site 62
T508
E
Q
F
G
P
I
R
T
V
A
E
G
K
G
D
Site 63
T530
R
N
F
V
L
Q
G
T
L
S
G
D
F
T
P
Site 64
T536
G
T
L
S
G
D
F
T
P
I
T
Q
G
H
T
Site 65
T539
S
G
D
F
T
P
I
T
Q
G
H
T
D
E
L
Site 66
T560
A
S
K
S
Q
F
L
T
C
G
H
D
K
H
A
Site 67
S589
I
I
E
D
P
A
Q
S
S
G
F
H
P
S
G
Site 68
S590
I
E
D
P
A
Q
S
S
G
F
H
P
S
G
S
Site 69
T613
G
R
W
F
V
F
D
T
E
T
K
D
L
V
T
Site 70
T620
T
E
T
K
D
L
V
T
V
H
T
D
G
N
E
Site 71
S630
T
D
G
N
E
Q
L
S
V
M
R
Y
S
P
D
Site 72
Y634
E
Q
L
S
V
M
R
Y
S
P
D
G
N
F
L
Site 73
S635
Q
L
S
V
M
R
Y
S
P
D
G
N
F
L
A
Site 74
Y651
G
S
H
D
N
C
I
Y
I
Y
G
V
S
D
N
Site 75
Y653
H
D
N
C
I
Y
I
Y
G
V
S
D
N
G
R
Site 76
Y662
V
S
D
N
G
R
K
Y
T
R
V
G
K
C
S
Site 77
T663
S
D
N
G
R
K
Y
T
R
V
G
K
C
S
G
Site 78
S669
Y
T
R
V
G
K
C
S
G
H
S
S
F
I
T
Site 79
T676
S
G
H
S
S
F
I
T
H
L
D
W
S
V
N
Site 80
S684
H
L
D
W
S
V
N
S
Q
F
L
V
S
N
S
Site 81
S691
S
Q
F
L
V
S
N
S
G
D
Y
E
I
L
Y
Site 82
Y698
S
G
D
Y
E
I
L
Y
W
V
P
S
A
C
K
Site 83
S709
S
A
C
K
Q
V
V
S
V
E
T
T
R
D
I
Site 84
Y721
R
D
I
E
W
A
T
Y
T
C
T
L
G
F
H
Site 85
S737
F
G
V
W
P
E
G
S
D
G
T
D
I
N
A
Site 86
Y768
G
K
V
H
L
F
S
Y
P
C
S
Q
F
R
A
Site 87
S771
H
L
F
S
Y
P
C
S
Q
F
R
A
P
S
H
Site 88
S777
C
S
Q
F
R
A
P
S
H
I
Y
G
G
H
S
Site 89
Y780
F
R
A
P
S
H
I
Y
G
G
H
S
S
H
V
Site 90
T788
G
G
H
S
S
H
V
T
N
V
D
F
L
C
E
Site 91
S801
C
E
D
S
H
L
I
S
T
G
G
K
D
T
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation