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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAAH
Full Name:
Fatty-acid amide hydrolase 1
Alias:
Anandamide amidohydrolase; FAAH1; FAAH-1; Fatty acid amide hydrolase; Fatty-acid amide hydrolase; Oleamide hydrolase
Type:
Hydrolase; EC 3.1.-.-
Mass (Da):
63070
Number AA:
UniProt ID:
O00519
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0016884
GO:0017064
PhosphoSite+
KinaseNET
Biological Process:
GO:0009062
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S32
A
A
V
A
L
R
W
S
G
R
R
T
A
R
G
Site 2
T36
L
R
W
S
G
R
R
T
A
R
G
A
V
V
R
Site 3
S71
L
Q
N
P
D
L
D
S
E
A
L
L
A
L
P
Site 4
S88
Q
L
V
Q
K
L
H
S
R
E
L
A
P
E
A
Site 5
T99
A
P
E
A
V
L
F
T
Y
V
G
K
A
W
E
Site 6
Y117
G
T
N
C
V
T
S
Y
L
A
D
C
E
T
Q
Site 7
T123
S
Y
L
A
D
C
E
T
Q
L
S
Q
A
P
R
Site 8
S126
A
D
C
E
T
Q
L
S
Q
A
P
R
Q
G
L
Site 9
Y147
S
L
K
E
C
F
T
Y
K
G
Q
D
S
T
L
Site 10
T153
T
Y
K
G
Q
D
S
T
L
G
L
S
L
N
E
Site 11
S157
Q
D
S
T
L
G
L
S
L
N
E
G
V
P
A
Site 12
S193
N
V
P
Q
S
M
F
S
Y
D
C
S
N
P
L
Site 13
Y194
V
P
Q
S
M
F
S
Y
D
C
S
N
P
L
F
Site 14
T204
S
N
P
L
F
G
Q
T
V
N
P
W
K
S
S
Site 15
S210
Q
T
V
N
P
W
K
S
S
K
S
P
G
G
S
Site 16
S211
T
V
N
P
W
K
S
S
K
S
P
G
G
S
S
Site 17
S213
N
P
W
K
S
S
K
S
P
G
G
S
S
G
G
Site 18
S217
S
S
K
S
P
G
G
S
S
G
G
E
G
A
L
Site 19
T257
G
I
C
G
L
K
P
T
G
N
R
L
S
K
S
Site 20
S262
K
P
T
G
N
R
L
S
K
S
G
L
K
G
C
Site 21
S264
T
G
N
R
L
S
K
S
G
L
K
G
C
V
Y
Site 22
S279
G
Q
E
A
V
R
L
S
V
G
P
M
A
R
D
Site 23
T308
D
M
F
R
L
D
P
T
V
P
P
L
P
F
R
Site 24
Y319
L
P
F
R
E
E
V
Y
T
S
S
Q
P
L
R
Site 25
T320
P
F
R
E
E
V
Y
T
S
S
Q
P
L
R
V
Site 26
S321
F
R
E
E
V
Y
T
S
S
Q
P
L
R
V
G
Site 27
S322
R
E
E
V
Y
T
S
S
Q
P
L
R
V
G
Y
Site 28
Y329
S
Q
P
L
R
V
G
Y
Y
E
T
D
N
Y
T
Site 29
Y330
Q
P
L
R
V
G
Y
Y
E
T
D
N
Y
T
M
Site 30
Y335
G
Y
Y
E
T
D
N
Y
T
M
P
S
P
A
M
Site 31
T336
Y
Y
E
T
D
N
Y
T
M
P
S
P
A
M
R
Site 32
S339
T
D
N
Y
T
M
P
S
P
A
M
R
R
A
V
Site 33
S352
A
V
L
E
T
K
Q
S
L
E
A
A
G
H
T
Site 34
S376
P
H
A
L
E
T
L
S
T
G
G
L
F
S
D
Site 35
T377
H
A
L
E
T
L
S
T
G
G
L
F
S
D
G
Site 36
T387
L
F
S
D
G
G
H
T
F
L
Q
N
F
K
G
Site 37
S430
K
P
L
L
P
R
L
S
A
F
L
S
N
M
K
Site 38
S434
P
R
L
S
A
F
L
S
N
M
K
S
R
S
A
Site 39
S438
A
F
L
S
N
M
K
S
R
S
A
G
K
L
W
Site 40
S440
L
S
N
M
K
S
R
S
A
G
K
L
W
E
L
Site 41
Y454
L
Q
H
E
I
E
V
Y
R
K
T
V
I
A
Q
Site 42
T457
E
I
E
V
Y
R
K
T
V
I
A
Q
W
R
A
Site 43
Y523
D
E
A
Q
M
E
H
Y
R
G
Y
F
G
D
I
Site 44
Y526
Q
M
E
H
Y
R
G
Y
F
G
D
I
W
D
K
Site 45
T573
R
E
V
E
R
L
M
T
P
E
K
Q
S
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation