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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PEX12
Full Name:
Peroxisome assembly protein 12
Alias:
Peroxin-12;Peroxisome assembly factor 3
Type:
Mass (Da):
40797
Number AA:
359
UniProt ID:
O00623
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
G
A
H
F
T
A
A
S
V
A
D
D
Q
P
S
Site 2
T50
V
L
A
E
S
N
P
T
H
Y
G
F
L
W
R
Site 3
Y74
D
L
L
L
Q
Q
H
Y
L
S
R
T
S
A
S
Site 4
S76
L
L
Q
Q
H
Y
L
S
R
T
S
A
S
F
S
Site 5
T78
Q
Q
H
Y
L
S
R
T
S
A
S
F
S
E
N
Site 6
S79
Q
H
Y
L
S
R
T
S
A
S
F
S
E
N
F
Site 7
S81
Y
L
S
R
T
S
A
S
F
S
E
N
F
Y
G
Site 8
S83
S
R
T
S
A
S
F
S
E
N
F
Y
G
L
K
Site 9
S100
V
M
G
D
T
H
K
S
Q
R
L
A
S
A
G
Site 10
S105
H
K
S
Q
R
L
A
S
A
G
L
P
K
Q
Q
Site 11
S135
V
K
L
E
K
L
V
S
S
L
R
E
E
D
E
Site 12
S136
K
L
E
K
L
V
S
S
L
R
E
E
D
E
Y
Site 13
Y143
S
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
Site 14
S144
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
R
Site 15
Y156
S
S
R
W
K
R
F
Y
R
A
F
L
A
A
Y
Site 16
S190
L
G
K
A
Q
H
H
S
P
L
L
R
L
A
G
Site 17
S219
E
H
K
P
A
K
A
S
M
M
Q
Q
P
A
R
Site 18
S227
M
M
Q
Q
P
A
R
S
V
S
E
K
I
N
S
Site 19
S229
Q
Q
P
A
R
S
V
S
E
K
I
N
S
A
L
Site 20
S234
S
V
S
E
K
I
N
S
A
L
K
K
A
V
G
Site 21
Y265
L
Q
F
L
D
W
W
Y
S
S
E
N
Q
E
T
Site 22
T272
Y
S
S
E
N
Q
E
T
I
K
S
L
T
A
L
Site 23
S275
E
N
Q
E
T
I
K
S
L
T
A
L
P
T
P
Site 24
T277
Q
E
T
I
K
S
L
T
A
L
P
T
P
P
P
Site 25
T281
K
S
L
T
A
L
P
T
P
P
P
P
V
H
L
Site 26
Y290
P
P
P
V
H
L
D
Y
N
S
D
S
P
L
L
Site 27
S292
P
V
H
L
D
Y
N
S
D
S
P
L
L
P
K
Site 28
S294
H
L
D
Y
N
S
D
S
P
L
L
P
K
M
K
Site 29
T315
R
K
T
R
V
N
D
T
V
L
A
T
S
G
Y
Site 30
T342
S
H
Q
A
C
P
I
T
G
Y
P
T
E
V
Q
Site 31
Y344
Q
A
C
P
I
T
G
Y
P
T
E
V
Q
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation