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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIR
Full Name:
Pirin
Alias:
Probable quercetin 2,3-dioxygenase PIR
Type:
Mass (Da):
32095
Number AA:
290
UniProt ID:
O00625
International Prot ID:
IPI00012575
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003712
GO:0005488
GO:0005506
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006351
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
G
S
S
K
K
V
T
L
S
V
L
S
R
E
Site 2
S10
S
S
K
K
V
T
L
S
V
L
S
R
E
Q
S
Site 3
S13
K
V
T
L
S
V
L
S
R
E
Q
S
E
G
V
Site 4
S17
S
V
L
S
R
E
Q
S
E
G
V
G
A
R
V
Site 5
S27
V
G
A
R
V
R
R
S
I
G
R
P
E
L
K
Site 6
T63
H
P
H
R
G
F
E
T
V
S
Y
L
L
E
G
Site 7
S65
H
R
G
F
E
T
V
S
Y
L
L
E
G
G
S
Site 8
Y66
R
G
F
E
T
V
S
Y
L
L
E
G
G
S
M
Site 9
S72
S
Y
L
L
E
G
G
S
M
A
H
E
D
F
C
Site 10
S107
L
H
A
E
M
P
C
S
E
E
P
A
H
G
L
Site 11
S123
L
W
V
N
L
R
S
S
E
K
M
V
E
P
Q
Site 12
Y131
E
K
M
V
E
P
Q
Y
Q
E
L
K
S
E
E
Site 13
S136
P
Q
Y
Q
E
L
K
S
E
E
I
P
K
P
S
Site 14
T148
K
P
S
K
D
G
V
T
V
A
V
I
S
G
E
Site 15
S161
G
E
A
L
G
I
K
S
K
V
Y
T
R
T
P
Site 16
Y164
L
G
I
K
S
K
V
Y
T
R
T
P
T
L
Y
Site 17
T165
G
I
K
S
K
V
Y
T
R
T
P
T
L
Y
L
Site 18
T167
K
S
K
V
Y
T
R
T
P
T
L
Y
L
D
F
Site 19
T169
K
V
Y
T
R
T
P
T
L
Y
L
D
F
K
L
Site 20
Y171
Y
T
R
T
P
T
L
Y
L
D
F
K
L
D
P
Site 21
S183
L
D
P
G
A
K
H
S
Q
P
I
P
K
G
W
Site 22
Y195
K
G
W
T
S
F
I
Y
T
I
S
G
D
V
Y
Site 23
Y202
Y
T
I
S
G
D
V
Y
I
G
P
D
D
A
Q
Site 24
T217
Q
K
I
E
P
H
H
T
A
V
L
G
E
G
D
Site 25
S225
A
V
L
G
E
G
D
S
V
Q
V
E
N
K
D
Site 26
T260
H
G
P
F
V
M
N
T
N
E
E
I
S
Q
A
Site 27
T283
N
G
F
E
R
A
K
T
W
K
S
K
I
G
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation