KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NFIB
Full Name:
Nuclear factor 1 B-type
Alias:
CCAAT-box binding transcription factor; CTF; NF1-B; NF-I/B; NFI-B; NFIB2; NFIB3; NFI-RED; Nuclear factor 1/B; Nuclear factor I/B; TGGCA-binding protein
Type:
Mass (Da):
47442
Number AA:
420
UniProt ID:
O00712
International Prot ID:
IPI00473116
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y3
_
_
_
_
_
M
M
Y
S
P
I
C
L
T
Q
Site 2
S4
_
_
_
_
M
M
Y
S
P
I
C
L
T
Q
D
Site 3
Y41
L
Q
A
R
K
R
K
Y
F
K
K
H
E
K
R
Site 4
S50
K
K
H
E
K
R
M
S
K
D
E
E
R
A
V
Site 5
S63
A
V
K
D
E
L
L
S
E
K
P
E
I
K
Q
Site 6
Y88
R
K
D
I
R
Q
E
Y
R
E
D
F
V
L
T
Site 7
T95
Y
R
E
D
F
V
L
T
V
T
G
K
K
H
P
Site 8
S107
K
H
P
C
C
V
L
S
N
P
D
Q
K
G
K
Site 9
S145
F
K
G
I
P
L
E
S
T
D
G
E
R
L
M
Site 10
T146
K
G
I
P
L
E
S
T
D
G
E
R
L
M
K
Site 11
S154
D
G
E
R
L
M
K
S
P
H
C
T
N
P
A
Site 12
T170
C
V
Q
P
H
H
I
T
V
S
V
K
E
L
D
Site 13
S172
Q
P
H
H
I
T
V
S
V
K
E
L
D
L
F
Site 14
Y183
L
D
L
F
L
A
Y
Y
V
Q
E
Q
D
S
G
Site 15
S189
Y
Y
V
Q
E
Q
D
S
G
Q
S
G
S
P
S
Site 16
S192
Q
E
Q
D
S
G
Q
S
G
S
P
S
H
N
D
Site 17
S194
Q
D
S
G
Q
S
G
S
P
S
H
N
D
P
A
Site 18
S196
S
G
Q
S
G
S
P
S
H
N
D
P
A
K
N
Site 19
Y207
P
A
K
N
P
P
G
Y
L
E
D
S
F
V
K
Site 20
S211
P
P
G
Y
L
E
D
S
F
V
K
S
G
V
F
Site 21
S215
L
E
D
S
F
V
K
S
G
V
F
N
V
S
E
Site 22
S221
K
S
G
V
F
N
V
S
E
L
V
R
V
S
R
Site 23
S227
V
S
E
L
V
R
V
S
R
T
P
I
T
Q
G
Site 24
T229
E
L
V
R
V
S
R
T
P
I
T
Q
G
T
G
Site 25
T232
R
V
S
R
T
P
I
T
Q
G
T
G
V
N
F
Site 26
T235
R
T
P
I
T
Q
G
T
G
V
N
F
P
I
G
Site 27
Y249
G
E
I
P
S
Q
P
Y
Y
H
D
M
N
S
G
Site 28
Y250
E
I
P
S
Q
P
Y
Y
H
D
M
N
S
G
V
Site 29
S255
P
Y
Y
H
D
M
N
S
G
V
N
L
Q
R
S
Site 30
S262
S
G
V
N
L
Q
R
S
L
S
S
P
P
S
S
Site 31
S264
V
N
L
Q
R
S
L
S
S
P
P
S
S
K
R
Site 32
S265
N
L
Q
R
S
L
S
S
P
P
S
S
K
R
P
Site 33
S268
R
S
L
S
S
P
P
S
S
K
R
P
K
T
I
Site 34
S269
S
L
S
S
P
P
S
S
K
R
P
K
T
I
S
Site 35
T274
P
S
S
K
R
P
K
T
I
S
I
D
E
N
M
Site 36
S276
S
K
R
P
K
T
I
S
I
D
E
N
M
E
P
Site 37
S284
I
D
E
N
M
E
P
S
P
T
G
D
F
Y
P
Site 38
T286
E
N
M
E
P
S
P
T
G
D
F
Y
P
S
P
Site 39
Y290
P
S
P
T
G
D
F
Y
P
S
P
S
S
P
A
Site 40
S292
P
T
G
D
F
Y
P
S
P
S
S
P
A
A
G
Site 41
S294
G
D
F
Y
P
S
P
S
S
P
A
A
G
S
R
Site 42
S295
D
F
Y
P
S
P
S
S
P
A
A
G
S
R
T
Site 43
S300
P
S
S
P
A
A
G
S
R
T
W
H
E
R
D
Site 44
S311
H
E
R
D
Q
D
M
S
S
P
T
T
M
K
K
Site 45
S312
E
R
D
Q
D
M
S
S
P
T
T
M
K
K
P
Site 46
T314
D
Q
D
M
S
S
P
T
T
M
K
K
P
E
K
Site 47
T315
Q
D
M
S
S
P
T
T
M
K
K
P
E
K
P
Site 48
S325
K
P
E
K
P
L
F
S
S
A
S
P
Q
D
S
Site 49
S326
P
E
K
P
L
F
S
S
A
S
P
Q
D
S
S
Site 50
S328
K
P
L
F
S
S
A
S
P
Q
D
S
S
P
R
Site 51
S332
S
S
A
S
P
Q
D
S
S
P
R
L
S
T
F
Site 52
S333
S
A
S
P
Q
D
S
S
P
R
L
S
T
F
P
Site 53
S337
Q
D
S
S
P
R
L
S
T
F
P
Q
H
H
H
Site 54
T338
D
S
S
P
R
L
S
T
F
P
Q
H
H
H
P
Site 55
S356
G
V
A
H
S
V
I
S
T
R
T
P
P
P
P
Site 56
T357
V
A
H
S
V
I
S
T
R
T
P
P
P
P
S
Site 57
T359
H
S
V
I
S
T
R
T
P
P
P
P
S
P
L
Site 58
S364
T
R
T
P
P
P
P
S
P
L
P
F
P
T
Q
Site 59
T370
P
S
P
L
P
F
P
T
Q
A
I
L
P
P
A
Site 60
S379
A
I
L
P
P
A
P
S
S
Y
F
S
H
P
T
Site 61
Y381
L
P
P
A
P
S
S
Y
F
S
H
P
T
I
R
Site 62
S383
P
A
P
S
S
Y
F
S
H
P
T
I
R
Y
P
Site 63
T386
S
S
Y
F
S
H
P
T
I
R
Y
P
P
H
L
Site 64
Y389
F
S
H
P
T
I
R
Y
P
P
H
L
N
P
Q
Site 65
T398
P
H
L
N
P
Q
D
T
L
K
N
Y
V
P
S
Site 66
Y402
P
Q
D
T
L
K
N
Y
V
P
S
Y
D
P
S
Site 67
S405
T
L
K
N
Y
V
P
S
Y
D
P
S
S
P
Q
Site 68
Y406
L
K
N
Y
V
P
S
Y
D
P
S
S
P
Q
T
Site 69
S409
Y
V
P
S
Y
D
P
S
S
P
Q
T
S
Q
S
Site 70
S410
V
P
S
Y
D
P
S
S
P
Q
T
S
Q
S
W
Site 71
T413
Y
D
P
S
S
P
Q
T
S
Q
S
W
Y
L
G
Site 72
S414
D
P
S
S
P
Q
T
S
Q
S
W
Y
L
G
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation