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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
E2F3
Full Name:
Transcription factor E2F3
Alias:
E2F-3; KIAA0075
Type:
Uncharacterized protein
Mass (Da):
49162
Number AA:
465
UniProt ID:
O00716
International Prot ID:
IPI00290663
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005667
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007049
GO:0006367
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T62
G
A
Y
I
Q
I
L
T
T
N
T
S
T
T
S
Site 2
S66
Q
I
L
T
T
N
T
S
T
T
S
C
S
S
S
Site 3
T67
I
L
T
T
N
T
S
T
T
S
C
S
S
S
L
Site 4
T68
L
T
T
N
T
S
T
T
S
C
S
S
S
L
Q
Site 5
S69
T
T
N
T
S
T
T
S
C
S
S
S
L
Q
S
Site 6
S71
N
T
S
T
T
S
C
S
S
S
L
Q
S
G
A
Site 7
S72
T
S
T
T
S
C
S
S
S
L
Q
S
G
A
V
Site 8
S73
S
T
T
S
C
S
S
S
L
Q
S
G
A
V
A
Site 9
S97
G
A
E
Q
T
A
G
S
L
L
Y
T
T
P
H
Site 10
Y100
Q
T
A
G
S
L
L
Y
T
T
P
H
G
P
S
Site 11
T101
T
A
G
S
L
L
Y
T
T
P
H
G
P
S
S
Site 12
T102
A
G
S
L
L
Y
T
T
P
H
G
P
S
S
R
Site 13
S108
T
T
P
H
G
P
S
S
R
A
G
L
L
Q
Q
Site 14
S124
P
A
L
G
R
G
G
S
G
G
G
G
G
P
P
Site 15
S141
R
R
L
E
L
G
E
S
G
H
Q
Y
L
S
D
Site 16
Y145
L
G
E
S
G
H
Q
Y
L
S
D
G
L
K
T
Site 17
S147
E
S
G
H
Q
Y
L
S
D
G
L
K
T
P
K
Site 18
T152
Y
L
S
D
G
L
K
T
P
K
G
K
G
R
A
Site 19
S163
K
G
R
A
A
L
R
S
P
D
S
P
K
T
P
Site 20
S166
A
A
L
R
S
P
D
S
P
K
T
P
K
S
P
Site 21
T169
R
S
P
D
S
P
K
T
P
K
S
P
S
E
K
Site 22
S172
D
S
P
K
T
P
K
S
P
S
E
K
T
R
Y
Site 23
S174
P
K
T
P
K
S
P
S
E
K
T
R
Y
D
T
Site 24
T177
P
K
S
P
S
E
K
T
R
Y
D
T
S
L
G
Site 25
Y179
S
P
S
E
K
T
R
Y
D
T
S
L
G
L
L
Site 26
T181
S
E
K
T
R
Y
D
T
S
L
G
L
L
T
K
Site 27
S182
E
K
T
R
Y
D
T
S
L
G
L
L
T
K
K
Site 28
S195
K
K
F
I
Q
L
L
S
Q
S
P
D
G
V
L
Site 29
Y219
K
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Site 30
T222
K
R
R
I
Y
D
I
T
N
V
L
E
G
I
H
Site 31
S247
Q
W
M
G
C
S
L
S
E
D
G
G
M
L
A
Site 32
T264
Q
G
L
S
K
E
V
T
E
L
S
Q
E
E
K
Site 33
S267
S
K
E
V
T
E
L
S
Q
E
E
K
K
L
D
Site 34
S291
L
K
L
L
T
E
D
S
E
N
Q
R
L
A
Y
Site 35
Y298
S
E
N
Q
R
L
A
Y
V
T
Y
Q
D
I
R
Site 36
T300
N
Q
R
L
A
Y
V
T
Y
Q
D
I
R
K
I
Site 37
Y301
Q
R
L
A
Y
V
T
Y
Q
D
I
R
K
I
S
Site 38
S308
Y
Q
D
I
R
K
I
S
G
L
K
D
Q
T
V
Site 39
S331
T
R
L
E
V
P
D
S
I
E
S
L
Q
I
H
Site 40
S334
E
V
P
D
S
I
E
S
L
Q
I
H
L
A
S
Site 41
Y349
T
Q
G
P
I
E
V
Y
L
C
P
E
E
T
E
Site 42
T355
V
Y
L
C
P
E
E
T
E
T
H
S
P
M
K
Site 43
T357
L
C
P
E
E
T
E
T
H
S
P
M
K
T
N
Site 44
S359
P
E
E
T
E
T
H
S
P
M
K
T
N
N
Q
Site 45
T363
E
T
H
S
P
M
K
T
N
N
Q
D
H
N
G
Site 46
S377
G
N
I
P
K
P
A
S
K
D
L
A
S
T
N
Site 47
S382
P
A
S
K
D
L
A
S
T
N
S
G
H
S
D
Site 48
S385
K
D
L
A
S
T
N
S
G
H
S
D
C
S
V
Site 49
S388
A
S
T
N
S
G
H
S
D
C
S
V
S
M
G
Site 50
S391
N
S
G
H
S
D
C
S
V
S
M
G
N
L
S
Site 51
S393
G
H
S
D
C
S
V
S
M
G
N
L
S
P
L
Site 52
S398
S
V
S
M
G
N
L
S
P
L
A
S
P
A
N
Site 53
S402
G
N
L
S
P
L
A
S
P
A
N
L
L
Q
Q
Site 54
Y434
P
P
L
L
Q
E
D
Y
L
L
S
L
G
E
E
Site 55
S437
L
Q
E
D
Y
L
L
S
L
G
E
E
E
G
I
Site 56
S445
L
G
E
E
E
G
I
S
D
L
F
D
A
Y
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation