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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PDXK
Full Name:
Pyridoxal kinase
Alias:
C21orf124; C21orf97; FLJ21324; FLJ31940; MGC15873; PKH; PNK; PRED79; pyridoxal (pyridoxine, vitamin B6) kinase; Pyridoxine kinase
Type:
Kinase (non-protein); EC 2.7.1.35; Cofactor and Vitamin Metabolism - vitamin B6
Mass (Da):
35100
Number AA:
UniProt ID:
O00764
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0031403
GO:0000287
PhosphoSite+
KinaseNET
Biological Process:
GO:0008283
GO:0042823
GO:0008615
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
E
E
C
R
V
L
S
I
Q
S
H
V
I
R
Site 2
Y18
Q
S
H
V
I
R
G
Y
V
G
N
R
A
A
T
Site 3
S59
W
K
G
Q
V
L
N
S
D
E
L
Q
E
L
Y
Site 4
Y66
S
D
E
L
Q
E
L
Y
E
G
L
R
L
N
N
Site 5
Y77
R
L
N
N
M
N
K
Y
D
Y
V
L
T
G
Y
Site 6
Y79
N
N
M
N
K
Y
D
Y
V
L
T
G
Y
T
R
Site 7
Y84
Y
D
Y
V
L
T
G
Y
T
R
D
K
S
F
L
Site 8
S89
T
G
Y
T
R
D
K
S
F
L
A
M
V
V
D
Site 9
Y110
Q
Q
N
P
R
L
V
Y
V
C
D
P
V
L
G
Site 10
Y127
W
D
G
E
G
S
M
Y
V
P
E
D
L
L
P
Site 11
Y136
P
E
D
L
L
P
V
Y
K
E
K
V
V
P
L
Site 12
S158
Q
F
E
A
E
L
L
S
G
R
K
I
H
S
Q
Site 13
S164
L
S
G
R
K
I
H
S
Q
E
E
A
L
R
V
Site 14
T182
L
H
S
M
G
P
D
T
V
V
I
T
S
S
D
Site 15
T186
G
P
D
T
V
V
I
T
S
S
D
L
P
S
P
Site 16
S187
P
D
T
V
V
I
T
S
S
D
L
P
S
P
Q
Site 17
S188
D
T
V
V
I
T
S
S
D
L
P
S
P
Q
G
Site 18
S192
I
T
S
S
D
L
P
S
P
Q
G
S
N
Y
L
Site 19
S196
D
L
P
S
P
Q
G
S
N
Y
L
I
V
L
G
Site 20
Y198
P
S
P
Q
G
S
N
Y
L
I
V
L
G
S
Q
Site 21
S204
N
Y
L
I
V
L
G
S
Q
R
R
R
N
P
A
Site 22
S213
R
R
R
N
P
A
G
S
V
V
M
E
R
I
R
Site 23
T259
L
K
V
A
C
E
K
T
V
S
T
L
H
H
V
Site 24
S261
V
A
C
E
K
T
V
S
T
L
H
H
V
L
Q
Site 25
T262
A
C
E
K
T
V
S
T
L
H
H
V
L
Q
R
Site 26
T270
L
H
H
V
L
Q
R
T
I
Q
C
A
K
A
Q
Site 27
S285
A
G
E
G
V
R
P
S
P
M
Q
L
E
L
R
Site 28
S296
L
E
L
R
M
V
Q
S
K
R
D
I
E
D
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation