KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PPAP2B
Full Name:
Lipid phosphate phosphohydrolase 3
Alias:
Dri42; EC 3.1.3.4; LPP3; PAP- 2b; PAP2b; PAP-2b; PAP2-b; PAP2-beta; Phosphatidate phosphohydrolase type 2b; Phosphatidic acid phosphatase 2b; Phosphatidic acid phosphatase type 2B; Vascular endothelial growth factor and type I collagen-inducible protein; VCIP
Type:
Plasma membrane, Golgi apparatus, Integral, Membrane protein
Mass (Da):
35116
Number AA:
311
UniProt ID:
O14495
International Prot ID:
IPI00021453
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0008195
GO:0004721
GO:0042392
PhosphoSite+
KinaseNET
Biological Process:
GO:0008354
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
D
K
A
I
V
P
E
S
K
N
G
G
S
P
A
Site 2
S19
P
E
S
K
N
G
G
S
P
A
L
N
N
N
P
Site 3
S29
L
N
N
N
P
R
R
S
G
S
K
R
V
L
L
Site 4
S31
N
N
P
R
R
S
G
S
K
R
V
L
L
I
C
Site 5
S57
P
F
L
I
I
E
T
S
T
I
K
P
Y
H
R
Site 6
Y62
E
T
S
T
I
K
P
Y
H
R
G
F
Y
C
N
Site 7
Y67
K
P
Y
H
R
G
F
Y
C
N
D
E
S
I
K
Site 8
Y75
C
N
D
E
S
I
K
Y
P
L
K
T
G
E
T
Site 9
Y109
T
G
E
F
Y
R
I
Y
Y
L
K
K
S
R
S
Site 10
Y110
G
E
F
Y
R
I
Y
Y
L
K
K
S
R
S
T
Site 11
S114
R
I
Y
Y
L
K
K
S
R
S
T
I
Q
N
P
Site 12
S116
Y
Y
L
K
K
S
R
S
T
I
Q
N
P
Y
V
Site 13
T117
Y
L
K
K
S
R
S
T
I
Q
N
P
Y
V
A
Site 14
Y122
R
S
T
I
Q
N
P
Y
V
A
A
L
Y
K
Q
Site 15
S160
R
L
R
P
H
F
L
S
V
C
N
P
D
F
S
Site 16
S167
S
V
C
N
P
D
F
S
Q
I
N
C
S
E
G
Site 17
Y179
S
E
G
Y
I
Q
N
Y
R
C
R
G
D
D
S
Site 18
S186
Y
R
C
R
G
D
D
S
K
V
Q
E
A
R
K
Site 19
S194
K
V
Q
E
A
R
K
S
F
F
S
G
H
A
S
Site 20
S197
E
A
R
K
S
F
F
S
G
H
A
S
F
S
M
Site 21
Y213
T
M
L
Y
L
V
L
Y
L
Q
A
R
F
T
W
Site 22
S244
M
A
F
Y
T
G
L
S
R
V
S
D
H
K
H
Site 23
S247
Y
T
G
L
S
R
V
S
D
H
K
H
H
P
S
Site 24
T282
S
D
L
F
K
T
K
T
T
L
S
L
P
A
P
Site 25
S285
F
K
T
K
T
T
L
S
L
P
A
P
A
I
R
Site 26
S297
A
I
R
K
E
I
L
S
P
V
D
I
I
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation