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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARID1A
Full Name:
AT-rich interactive domain-containing protein 1A
Alias:
ARI1A; AT rich interactive domain 1A; B120; BAF250; BAF250a; BRG1-associated factor 250; BRG1-associated factor 250a; C10rf4; C1orf4; HELD; Osa homolog 1; P270; SMARCF1; SMF1; SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1; SWI-like; SWI-like protein; SWI-SNF complex protein p270
Type:
Nuclear receptor co-regulator; DNA binding protein
Mass (Da):
242045
Number AA:
2285
UniProt ID:
O14497
International Prot ID:
IPI00643722
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016514
GO:0005634
GO:0016514
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0016563
PhosphoSite+
KinaseNET
Biological Process:
GO:0030521
GO:0048096
GO:0030520
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
Q
V
A
P
A
A
A
S
S
L
G
N
P
P
P
Site 2
S12
V
A
P
A
A
A
S
S
L
G
N
P
P
P
P
Site 3
S22
N
P
P
P
P
P
P
S
E
L
K
K
A
E
Q
Site 4
S58
K
A
A
A
G
Q
E
S
E
G
P
A
V
G
P
Site 5
S79
E
L
Q
D
G
A
E
S
N
G
G
G
G
G
G
Site 6
S90
G
G
G
G
G
A
G
S
G
G
G
P
G
A
E
Site 7
T118
P
A
L
N
N
N
L
T
E
P
P
G
G
G
G
Site 8
S128
P
G
G
G
G
G
G
S
S
D
G
V
G
A
P
Site 9
S129
G
G
G
G
G
G
S
S
D
G
V
G
A
P
P
Site 10
Y148
A
A
L
P
P
P
A
Y
G
F
G
Q
P
Y
G
Site 11
Y154
A
Y
G
F
G
Q
P
Y
G
R
S
P
S
A
V
Site 12
S157
F
G
Q
P
Y
G
R
S
P
S
A
V
A
A
A
Site 13
S159
Q
P
Y
G
R
S
P
S
A
V
A
A
A
A
A
Site 14
S178
Q
Q
H
G
G
Q
Q
S
P
G
L
A
A
L
Q
Site 15
Y195
G
G
G
G
L
E
P
Y
A
G
P
Q
Q
N
S
Site 16
Y212
H
G
F
P
N
H
Q
Y
N
S
Y
Y
P
N
R
Site 17
Y215
P
N
H
Q
Y
N
S
Y
Y
P
N
R
S
A
Y
Site 18
Y216
N
H
Q
Y
N
S
Y
Y
P
N
R
S
A
Y
P
Site 19
S220
N
S
Y
Y
P
N
R
S
A
Y
P
P
P
A
P
Site 20
Y222
Y
Y
P
N
R
S
A
Y
P
P
P
A
P
A
Y
Site 21
Y229
Y
P
P
P
A
P
A
Y
A
L
S
S
P
R
G
Site 22
S232
P
A
P
A
Y
A
L
S
S
P
R
G
G
T
P
Site 23
S233
A
P
A
Y
A
L
S
S
P
R
G
G
T
P
G
Site 24
T238
L
S
S
P
R
G
G
T
P
G
S
G
A
A
A
Site 25
S241
P
R
G
G
T
P
G
S
G
A
A
A
A
A
G
Site 26
S249
G
A
A
A
A
A
G
S
K
P
P
P
S
S
S
Site 27
S254
A
G
S
K
P
P
P
S
S
S
A
S
A
S
S
Site 28
S255
G
S
K
P
P
P
S
S
S
A
S
A
S
S
S
Site 29
S256
S
K
P
P
P
S
S
S
A
S
A
S
S
S
S
Site 30
S258
P
P
P
S
S
S
A
S
A
S
S
S
S
S
S
Site 31
S260
P
S
S
S
A
S
A
S
S
S
S
S
S
F
A
Site 32
S261
S
S
S
A
S
A
S
S
S
S
S
S
F
A
Q
Site 33
S262
S
S
A
S
A
S
S
S
S
S
S
F
A
Q
Q
Site 34
S263
S
A
S
A
S
S
S
S
S
S
F
A
Q
Q
R
Site 35
S264
A
S
A
S
S
S
S
S
S
F
A
Q
Q
R
F
Site 36
S265
S
A
S
S
S
S
S
S
F
A
Q
Q
R
F
G
Site 37
S280
A
M
G
G
G
G
P
S
A
A
G
G
G
T
P
Site 38
T286
P
S
A
A
G
G
G
T
P
Q
P
T
A
T
P
Site 39
T290
G
G
G
T
P
Q
P
T
A
T
P
T
L
N
Q
Site 40
T292
G
T
P
Q
P
T
A
T
P
T
L
N
Q
L
L
Site 41
T294
P
Q
P
T
A
T
P
T
L
N
Q
L
L
T
S
Site 42
T300
P
T
L
N
Q
L
L
T
S
P
S
S
A
R
G
Site 43
S301
T
L
N
Q
L
L
T
S
P
S
S
A
R
G
Y
Site 44
S303
N
Q
L
L
T
S
P
S
S
A
R
G
Y
Q
G
Site 45
S304
Q
L
L
T
S
P
S
S
A
R
G
Y
Q
G
Y
Site 46
Y308
S
P
S
S
A
R
G
Y
Q
G
Y
P
G
G
D
Site 47
Y311
S
A
R
G
Y
Q
G
Y
P
G
G
D
Y
S
G
Site 48
Y316
Q
G
Y
P
G
G
D
Y
S
G
G
P
Q
D
G
Site 49
S317
G
Y
P
G
G
D
Y
S
G
G
P
Q
D
G
G
Site 50
S334
K
G
P
A
D
M
A
S
Q
C
W
G
A
A
A
Site 51
S357
S
G
G
A
Q
Q
R
S
H
H
A
P
M
S
P
Site 52
S363
R
S
H
H
A
P
M
S
P
G
S
S
G
G
G
Site 53
S366
H
A
P
M
S
P
G
S
S
G
G
G
G
Q
P
Site 54
S367
A
P
M
S
P
G
S
S
G
G
G
G
Q
P
L
Site 55
T377
G
G
Q
P
L
A
R
T
P
Q
P
S
S
P
M
Site 56
S381
L
A
R
T
P
Q
P
S
S
P
M
D
Q
M
G
Site 57
S382
A
R
T
P
Q
P
S
S
P
M
D
Q
M
G
K
Site 58
Y401
P
Y
G
G
T
N
P
Y
S
Q
Q
Q
G
P
P
Site 59
S402
Y
G
G
T
N
P
Y
S
Q
Q
Q
G
P
P
S
Site 60
S409
S
Q
Q
Q
G
P
P
S
G
P
Q
Q
G
H
G
Site 61
Y417
G
P
Q
Q
G
H
G
Y
P
G
Q
P
Y
G
S
Site 62
Y422
H
G
Y
P
G
Q
P
Y
G
S
Q
T
P
Q
R
Site 63
S424
Y
P
G
Q
P
Y
G
S
Q
T
P
Q
R
Y
P
Site 64
T426
G
Q
P
Y
G
S
Q
T
P
Q
R
Y
P
M
T
Site 65
Y430
G
S
Q
T
P
Q
R
Y
P
M
T
M
Q
G
R
Site 66
T433
T
P
Q
R
Y
P
M
T
M
Q
G
R
A
Q
S
Site 67
S440
T
M
Q
G
R
A
Q
S
A
M
G
G
L
S
Y
Site 68
S446
Q
S
A
M
G
G
L
S
Y
T
Q
Q
I
P
P
Site 69
Y447
S
A
M
G
G
L
S
Y
T
Q
Q
I
P
P
Y
Site 70
T448
A
M
G
G
L
S
Y
T
Q
Q
I
P
P
Y
G
Site 71
Y454
Y
T
Q
Q
I
P
P
Y
G
Q
Q
G
P
S
G
Site 72
S460
P
Y
G
Q
Q
G
P
S
G
Y
G
Q
Q
G
Q
Site 73
T468
G
Y
G
Q
Q
G
Q
T
P
Y
Y
N
Q
Q
S
Site 74
Y470
G
Q
Q
G
Q
T
P
Y
Y
N
Q
Q
S
P
H
Site 75
Y471
Q
Q
G
Q
T
P
Y
Y
N
Q
Q
S
P
H
P
Site 76
Y485
P
Q
Q
Q
Q
P
P
Y
S
Q
Q
P
P
S
Q
Site 77
S486
Q
Q
Q
Q
P
P
Y
S
Q
Q
P
P
S
Q
T
Site 78
S491
P
Y
S
Q
Q
P
P
S
Q
T
P
H
A
Q
P
Site 79
T493
S
Q
Q
P
P
S
Q
T
P
H
A
Q
P
S
Y
Site 80
S499
Q
T
P
H
A
Q
P
S
Y
Q
Q
Q
P
Q
S
Site 81
Y500
T
P
H
A
Q
P
S
Y
Q
Q
Q
P
Q
S
Q
Site 82
S506
S
Y
Q
Q
Q
P
Q
S
Q
P
P
Q
L
Q
S
Site 83
S513
S
Q
P
P
Q
L
Q
S
S
Q
P
P
Y
S
Q
Site 84
S514
Q
P
P
Q
L
Q
S
S
Q
P
P
Y
S
Q
Q
Site 85
Y518
L
Q
S
S
Q
P
P
Y
S
Q
Q
P
S
Q
P
Site 86
S519
Q
S
S
Q
P
P
Y
S
Q
Q
P
S
Q
P
P
Site 87
S523
P
P
Y
S
Q
Q
P
S
Q
P
P
H
Q
Q
S
Site 88
S530
S
Q
P
P
H
Q
Q
S
P
A
P
Y
P
S
Q
Site 89
Y534
H
Q
Q
S
P
A
P
Y
P
S
Q
Q
S
T
T
Site 90
S536
Q
S
P
A
P
Y
P
S
Q
Q
S
T
T
Q
Q
Site 91
T540
P
Y
P
S
Q
Q
S
T
T
Q
Q
H
P
Q
S
Site 92
S547
T
T
Q
Q
H
P
Q
S
Q
P
P
Y
S
Q
P
Site 93
Y551
H
P
Q
S
Q
P
P
Y
S
Q
P
Q
A
Q
S
Site 94
S552
P
Q
S
Q
P
P
Y
S
Q
P
Q
A
Q
S
P
Site 95
S558
Y
S
Q
P
Q
A
Q
S
P
Y
Q
Q
Q
Q
P
Site 96
T572
P
Q
Q
P
A
P
S
T
L
S
Q
Q
A
A
Y
Site 97
S574
Q
P
A
P
S
T
L
S
Q
Q
A
A
Y
P
Q
Site 98
Y579
T
L
S
Q
Q
A
A
Y
P
Q
P
Q
S
Q
Q
Site 99
S584
A
A
Y
P
Q
P
Q
S
Q
Q
S
Q
Q
T
A
Site 100
S587
P
Q
P
Q
S
Q
Q
S
Q
Q
T
A
Y
S
Q
Site 101
Y592
Q
Q
S
Q
Q
T
A
Y
S
Q
Q
R
F
P
P
Site 102
S593
Q
S
Q
Q
T
A
Y
S
Q
Q
R
F
P
P
P
Site 103
S604
F
P
P
P
Q
E
L
S
Q
D
S
F
G
S
Q
Site 104
S607
P
Q
E
L
S
Q
D
S
F
G
S
Q
A
S
S
Site 105
S610
L
S
Q
D
S
F
G
S
Q
A
S
S
A
P
S
Site 106
S613
D
S
F
G
S
Q
A
S
S
A
P
S
M
T
S
Site 107
S614
S
F
G
S
Q
A
S
S
A
P
S
M
T
S
S
Site 108
S617
S
Q
A
S
S
A
P
S
M
T
S
S
K
G
G
Site 109
S621
S
A
P
S
M
T
S
S
K
G
G
Q
E
D
M
Site 110
S631
G
Q
E
D
M
N
L
S
L
Q
S
R
P
S
S
Site 111
S634
D
M
N
L
S
L
Q
S
R
P
S
S
L
P
D
Site 112
S637
L
S
L
Q
S
R
P
S
S
L
P
D
L
S
G
Site 113
S638
S
L
Q
S
R
P
S
S
L
P
D
L
S
G
S
Site 114
S643
P
S
S
L
P
D
L
S
G
S
I
D
D
L
P
Site 115
S645
S
L
P
D
L
S
G
S
I
D
D
L
P
M
G
Site 116
S658
M
G
T
E
G
A
L
S
P
G
V
S
T
S
G
Site 117
T663
A
L
S
P
G
V
S
T
S
G
I
S
S
S
Q
Site 118
S664
L
S
P
G
V
S
T
S
G
I
S
S
S
Q
G
Site 119
S668
V
S
T
S
G
I
S
S
S
Q
G
E
Q
S
N
Site 120
S669
S
T
S
G
I
S
S
S
Q
G
E
Q
S
N
P
Site 121
S674
S
S
S
Q
G
E
Q
S
N
P
A
Q
S
P
F
Site 122
S679
E
Q
S
N
P
A
Q
S
P
F
S
P
H
T
S
Site 123
S682
N
P
A
Q
S
P
F
S
P
H
T
S
P
H
L
Site 124
T685
Q
S
P
F
S
P
H
T
S
P
H
L
P
G
I
Site 125
S686
S
P
F
S
P
H
T
S
P
H
L
P
G
I
R
Site 126
S696
L
P
G
I
R
G
P
S
P
S
P
V
G
S
P
Site 127
S698
G
I
R
G
P
S
P
S
P
V
G
S
P
A
S
Site 128
S702
P
S
P
S
P
V
G
S
P
A
S
V
A
Q
S
Site 129
S705
S
P
V
G
S
P
A
S
V
A
Q
S
R
S
G
Site 130
S709
S
P
A
S
V
A
Q
S
R
S
G
P
L
S
P
Site 131
S711
A
S
V
A
Q
S
R
S
G
P
L
S
P
A
A
Site 132
S715
Q
S
R
S
G
P
L
S
P
A
A
V
P
G
N
Site 133
S730
Q
M
P
P
R
P
P
S
G
Q
S
D
S
I
M
Site 134
S733
P
R
P
P
S
G
Q
S
D
S
I
M
H
P
S
Site 135
S735
P
P
S
G
Q
S
D
S
I
M
H
P
S
M
N
Site 136
S740
S
D
S
I
M
H
P
S
M
N
Q
S
S
I
A
Site 137
S744
M
H
P
S
M
N
Q
S
S
I
A
Q
D
R
G
Site 138
Y752
S
I
A
Q
D
R
G
Y
M
Q
R
N
P
Q
M
Site 139
Y762
R
N
P
Q
M
P
Q
Y
S
S
P
Q
P
G
S
Site 140
S763
N
P
Q
M
P
Q
Y
S
S
P
Q
P
G
S
A
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S
Site 293
T1863
Q
T
H
F
E
S
K
T
E
L
L
P
S
R
P
Site 294
S1868
S
K
T
E
L
L
P
S
R
P
H
A
P
C
P
Site 295
T1884
A
P
R
K
H
V
T
T
A
E
G
T
P
G
T
Site 296
T1888
H
V
T
T
A
E
G
T
P
G
T
T
D
Q
E
Site 297
T1891
T
A
E
G
T
P
G
T
T
D
Q
E
G
P
P
Site 298
T1908
G
P
P
E
K
R
I
T
A
T
M
D
D
M
L
Site 299
S1916
A
T
M
D
D
M
L
S
T
R
S
S
T
L
T
Site 300
S1920
D
M
L
S
T
R
S
S
T
L
T
E
D
G
A
Site 301
T1921
M
L
S
T
R
S
S
T
L
T
E
D
G
A
K
Site 302
T1923
S
T
R
S
S
T
L
T
E
D
G
A
K
S
S
Site 303
S1930
T
E
D
G
A
K
S
S
E
A
I
K
E
S
S
Site 304
S1937
S
E
A
I
K
E
S
S
K
F
P
F
G
I
S
Site 305
S1944
S
K
F
P
F
G
I
S
P
A
Q
S
H
R
N
Site 306
S1948
F
G
I
S
P
A
Q
S
H
R
N
I
K
I
L
Site 307
S1961
I
L
E
D
E
P
H
S
K
D
E
T
P
L
C
Site 308
T1965
E
P
H
S
K
D
E
T
P
L
C
T
L
L
D
Site 309
S1992
S
N
T
I
R
S
L
S
F
V
P
G
N
D
F
Site 310
S2002
P
G
N
D
F
E
M
S
K
H
P
G
L
L
L
Site 311
T2030
E
R
K
Q
A
P
L
T
Y
E
K
E
E
E
Q
Site 312
S2074
I
S
G
Q
L
D
L
S
P
Y
P
E
S
I
C
Site 313
Y2076
G
Q
L
D
L
S
P
Y
P
E
S
I
C
L
P
Site 314
S2104
A
E
A
Q
D
P
F
S
T
L
G
P
N
A
V
Site 315
T2121
P
Q
R
L
V
L
E
T
L
S
K
L
S
I
Q
Site 316
S2123
R
L
V
L
E
T
L
S
K
L
S
I
Q
D
N
Site 317
S2142
I
L
A
T
P
P
F
S
R
L
E
K
L
Y
S
Site 318
S2149
S
R
L
E
K
L
Y
S
T
M
V
R
F
L
S
Site 319
T2150
R
L
E
K
L
Y
S
T
M
V
R
F
L
S
D
Site 320
S2156
S
T
M
V
R
F
L
S
D
R
K
N
P
V
C
Site 321
T2206
L
E
D
S
L
A
A
T
Q
F
Q
Q
S
Q
A
Site 322
S2211
A
A
T
Q
F
Q
Q
S
Q
A
S
L
L
H
M
Site 323
S2214
Q
F
Q
Q
S
Q
A
S
L
L
H
M
Q
N
P
Site 324
S2227
N
P
P
F
E
P
T
S
V
D
M
M
R
R
A
Site 325
Y2254
N
H
S
E
F
T
L
Y
E
S
R
L
L
D
I
Site 326
S2262
E
S
R
L
L
D
I
S
V
S
P
L
M
N
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation