PhosphoNET

           
Protein Info 
   
Short Name:  BHLHE40
Full Name:  Class E basic helix-loop-helix protein 40
Alias:  BHLH2; Class B basic helix-loop-helix 2; Class B basic helix-loop-helix protein 2; DEC1; Differentially expressed in chondrocytes 1; Differentially expressed in chondrocytes protein 1; Enhancer-of-split and hairy-related 2; Enhancer-of-split and hairy-related protein 2; SHARP-2; Stimulated by retinoic acid gene 13 protein
Type:  Uncharacterized protein
Mass (Da):  45510
Number AA:  412
UniProt ID:  O14503
International Prot ID:  IPI00021143
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0006350     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y29HGDLPGMYPAHMYQV
Site 2Y34GMYPAHMYQVYKSRR
Site 3Y37PAHMYQVYKSRRGIK
Site 4S46SRRGIKRSEDSKETY
Site 5Y53SEDSKETYKLPHRLI
Site 6S131GLQAGELSGRNVETG
Site 7Y156CAREVLQYLAKHENT
Site 8S168ENTRDLKSSQLVTHL
Site 9S169NTRDLKSSQLVTHLH
Site 10T173LKSSQLVTHLHRVVS
Site 11S180THLHRVVSELLQGGT
Site 12T187SELLQGGTSRKPSDP
Site 13S188ELLQGGTSRKPSDPA
Site 14S192GGTSRKPSDPAPKVM
Site 15S207DFKEKPSSPAKGSEG
Site 16S212PSSPAKGSEGPGKNC
Site 17T226CVPVIQRTFAHSSGE
Site 18S230IQRTFAHSSGEQSGS
Site 19S231QRTFAHSSGEQSGSD
Site 20S235AHSSGEQSGSDTDTD
Site 21S237SSGEQSGSDTDTDSG
Site 22T239GEQSGSDTDTDSGYG
Site 23T241QSGSDTDTDSGYGGE
Site 24S243GSDTDTDSGYGGESE
Site 25Y245DTDTDSGYGGESEKG
Site 26S256SEKGDLRSEQPCFKS
Site 27S263SEQPCFKSDHGRRFT
Site 28T270SDHGRRFTMGERIGA
Site 29S282IGAIKQESEEPPTKK
Site 30T287QESEEPPTKKNRMQL
Site 31S295KKNRMQLSDDEGHFT
Site 32T302SDDEGHFTSSDLISS
Site 33S303DDEGHFTSSDLISSP
Site 34S304DEGHFTSSDLISSPF
Site 35S308FTSSDLISSPFLGPH
Site 36S309TSSDLISSPFLGPHP
Site 37T346LEKCWYPTSVPVLYP
Site 38S383LMPQRLPSPLPAHPS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation