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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BAI1
Full Name:
Brain-specific angiogenesis inhibitor 1
Alias:
Brain-specific angiogenesis inhibitor 1
Type:
Mass (Da):
173514
Number AA:
1584
UniProt ID:
O14514
International Prot ID:
IPI00022333
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005911
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0016527
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007409
GO:0007155
GO:0008285
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S66
A
V
F
P
A
N
A
S
R
C
S
W
T
L
R
Site 2
S69
P
A
N
A
S
R
C
S
W
T
L
R
N
P
D
Site 3
Y80
R
N
P
D
P
R
R
Y
T
L
Y
M
K
V
A
Site 4
T81
N
P
D
P
R
R
Y
T
L
Y
M
K
V
A
K
Site 5
Y83
D
P
R
R
Y
T
L
Y
M
K
V
A
K
A
P
Site 6
S94
A
K
A
P
V
P
C
S
G
P
G
R
V
R
T
Site 7
T101
S
G
P
G
R
V
R
T
Y
Q
F
D
S
F
L
Site 8
Y102
G
P
G
R
V
R
T
Y
Q
F
D
S
F
L
E
Site 9
S106
V
R
T
Y
Q
F
D
S
F
L
E
S
T
R
T
Site 10
S110
Q
F
D
S
F
L
E
S
T
R
T
Y
L
G
V
Site 11
T113
S
F
L
E
S
T
R
T
Y
L
G
V
E
S
F
Site 12
Y114
F
L
E
S
T
R
T
Y
L
G
V
E
S
F
D
Site 13
S119
R
T
Y
L
G
V
E
S
F
D
E
V
L
R
L
Site 14
T166
R
A
G
P
P
G
P
T
D
D
F
S
V
E
Y
Site 15
Y173
T
D
D
F
S
V
E
Y
L
V
V
G
N
R
N
Site 16
S182
V
V
G
N
R
N
P
S
R
A
A
C
Q
M
L
Site 17
S200
L
D
A
C
L
A
G
S
R
S
S
H
P
C
G
Site 18
S203
C
L
A
G
S
R
S
S
H
P
C
G
I
M
Q
Site 19
T249
G
G
P
E
N
C
L
T
S
L
T
Q
D
R
G
Site 20
S250
G
P
E
N
C
L
T
S
L
T
Q
D
R
G
G
Site 21
T252
E
N
C
L
T
S
L
T
Q
D
R
G
G
H
G
Site 22
T285
G
G
G
L
Q
T
R
T
R
T
C
L
P
A
P
Site 23
T287
G
L
Q
T
R
T
R
T
C
L
P
A
P
G
V
Site 24
T320
A
C
G
P
A
G
R
T
S
S
R
S
Q
S
L
Site 25
S321
C
G
P
A
G
R
T
S
S
R
S
Q
S
L
R
Site 26
S322
G
P
A
G
R
T
S
S
R
S
Q
S
L
R
S
Site 27
S324
A
G
R
T
S
S
R
S
Q
S
L
R
S
T
D
Site 28
S326
R
T
S
S
R
S
Q
S
L
R
S
T
D
A
R
Site 29
T330
R
S
Q
S
L
R
S
T
D
A
R
R
R
E
E
Site 30
T352
F
G
F
P
A
P
Q
T
G
D
P
A
A
E
E
Site 31
S361
D
P
A
A
E
E
W
S
P
W
S
V
C
S
S
Site 32
T378
G
E
G
W
Q
T
R
T
R
F
C
V
S
S
S
Site 33
S383
T
R
T
R
F
C
V
S
S
S
Y
S
T
Q
C
Site 34
S384
R
T
R
F
C
V
S
S
S
Y
S
T
Q
C
S
Site 35
S385
T
R
F
C
V
S
S
S
Y
S
T
Q
C
S
G
Site 36
S387
F
C
V
S
S
S
Y
S
T
Q
C
S
G
P
L
Site 37
T388
C
V
S
S
S
Y
S
T
Q
C
S
G
P
L
R
Site 38
S391
S
S
Y
S
T
Q
C
S
G
P
L
R
E
Q
R
Site 39
S423
S
P
W
S
L
C
S
S
T
C
G
R
G
F
R
Site 40
T424
P
W
S
L
C
S
S
T
C
G
R
G
F
R
D
Site 41
T433
G
R
G
F
R
D
R
T
R
T
C
R
P
P
Q
Site 42
T435
G
F
R
D
R
T
R
T
C
R
P
P
Q
F
G
Site 43
S480
W
S
S
W
S
A
C
S
A
S
C
S
Q
G
R
Site 44
S482
S
W
S
A
C
S
A
S
C
S
Q
G
R
Q
Q
Site 45
S484
S
A
C
S
A
S
C
S
Q
G
R
Q
Q
R
T
Site 46
Y499
R
E
C
N
G
P
S
Y
G
G
A
E
C
Q
G
Site 47
T537
S
W
G
S
C
S
V
T
C
G
A
G
S
Q
R
Site 48
S542
S
V
T
C
G
A
G
S
Q
R
R
E
R
V
C
Site 49
S550
Q
R
R
E
R
V
C
S
G
P
F
F
G
G
A
Site 50
Y566
C
Q
G
P
Q
D
E
Y
R
Q
C
G
T
Q
R
Site 51
T609
V
R
C
P
R
N
A
T
G
L
I
L
R
R
C
Site 52
Y625
L
D
E
E
G
I
A
Y
W
E
P
P
T
Y
I
Site 53
Y631
A
Y
W
E
P
P
T
Y
I
R
C
V
S
I
D
Site 54
S673
I
Q
T
L
V
E
I
S
Q
D
G
T
S
Y
S
Site 55
T677
V
E
I
S
Q
D
G
T
S
Y
S
G
D
L
L
Site 56
S678
E
I
S
Q
D
G
T
S
Y
S
G
D
L
L
S
Site 57
S680
S
Q
D
G
T
S
Y
S
G
D
L
L
S
T
I
Site 58
S685
S
Y
S
G
D
L
L
S
T
I
D
V
L
R
N
Site 59
T694
I
D
V
L
R
N
M
T
E
I
F
R
R
A
Y
Site 60
Y701
T
E
I
F
R
R
A
Y
Y
S
P
T
P
G
D
Site 61
Y702
E
I
F
R
R
A
Y
Y
S
P
T
P
G
D
V
Site 62
S703
I
F
R
R
A
Y
Y
S
P
T
P
G
D
V
Q
Site 63
T705
R
R
A
Y
Y
S
P
T
P
G
D
V
Q
N
F
Site 64
Y763
M
K
D
L
R
D
A
Y
Q
V
T
D
N
L
V
Site 65
S785
A
S
G
A
T
D
I
S
F
P
M
K
G
W
R
Site 66
T794
P
M
K
G
W
R
A
T
G
D
W
A
K
V
P
Site 67
T806
K
V
P
E
D
R
V
T
V
S
K
S
V
F
S
Site 68
S808
P
E
D
R
V
T
V
S
K
S
V
F
S
T
G
Site 69
S810
D
R
V
T
V
S
K
S
V
F
S
T
G
L
T
Site 70
T856
N
S
K
V
I
S
V
T
V
K
P
P
P
R
S
Site 71
S863
T
V
K
P
P
P
R
S
L
R
T
P
L
E
I
Site 72
T866
P
P
P
R
S
L
R
T
P
L
E
I
E
F
A
Site 73
Y876
E
I
E
F
A
H
M
Y
N
G
T
T
N
Q
T
Site 74
T890
T
C
I
L
W
D
E
T
D
V
P
S
S
S
A
Site 75
S894
W
D
E
T
D
V
P
S
S
S
A
P
P
Q
L
Site 76
S895
D
E
T
D
V
P
S
S
S
A
P
P
Q
L
G
Site 77
S896
E
T
D
V
P
S
S
S
A
P
P
Q
L
G
P
Site 78
Y975
I
Y
V
S
V
W
R
Y
I
R
S
E
R
S
V
Site 79
Y1082
K
G
Y
S
T
M
N
Y
C
W
L
S
L
E
G
Site 80
S1119
L
V
F
N
K
L
V
S
K
D
G
I
T
D
K
Site 81
S1210
Q
E
E
G
N
G
D
S
G
G
S
F
Q
N
G
Site 82
S1213
G
N
G
D
S
G
G
S
F
Q
N
G
H
A
Q
Site 83
T1250
A
C
R
T
A
T
I
T
G
T
L
K
R
P
S
Site 84
T1252
R
T
A
T
I
T
G
T
L
K
R
P
S
L
P
Site 85
S1257
T
G
T
L
K
R
P
S
L
P
E
E
E
K
L
Site 86
T1274
A
H
A
K
G
P
P
T
N
F
N
S
L
P
A
Site 87
S1278
G
P
P
T
N
F
N
S
L
P
A
N
V
S
K
Site 88
S1284
N
S
L
P
A
N
V
S
K
L
H
L
H
G
S
Site 89
S1291
S
K
L
H
L
H
G
S
P
R
Y
P
G
G
P
Site 90
Y1294
H
L
H
G
S
P
R
Y
P
G
G
P
L
P
D
Site 91
S1306
L
P
D
F
P
N
H
S
L
T
L
K
R
D
K
Site 92
T1308
D
F
P
N
H
S
L
T
L
K
R
D
K
A
P
Site 93
S1317
K
R
D
K
A
P
K
S
S
F
V
G
D
G
D
Site 94
S1318
R
D
K
A
P
K
S
S
F
V
G
D
G
D
I
Site 95
S1331
D
I
F
K
K
L
D
S
E
L
S
R
A
Q
E
Site 96
S1334
K
K
L
D
S
E
L
S
R
A
Q
E
K
A
L
Site 97
T1343
A
Q
E
K
A
L
D
T
S
Y
V
I
L
P
T
Site 98
Y1345
E
K
A
L
D
T
S
Y
V
I
L
P
T
A
T
Site 99
T1350
T
S
Y
V
I
L
P
T
A
T
A
T
L
R
P
Site 100
T1354
I
L
P
T
A
T
A
T
L
R
P
K
P
K
E
Site 101
Y1365
K
P
K
E
E
P
K
Y
S
I
H
I
D
Q
M
Site 102
S1366
P
K
E
E
P
K
Y
S
I
H
I
D
Q
M
P
Site 103
T1375
H
I
D
Q
M
P
Q
T
R
L
I
H
L
S
T
Site 104
S1381
Q
T
R
L
I
H
L
S
T
A
P
E
A
S
L
Site 105
S1387
L
S
T
A
P
E
A
S
L
P
A
R
S
P
P
Site 106
S1392
E
A
S
L
P
A
R
S
P
P
S
R
Q
P
P
Site 107
S1395
L
P
A
R
S
P
P
S
R
Q
P
P
S
G
G
Site 108
S1400
P
P
S
R
Q
P
P
S
G
G
P
P
E
A
P
Site 109
S1438
N
L
E
P
A
P
P
S
L
G
D
P
G
E
P
Site 110
S1452
P
A
A
H
P
G
P
S
T
G
P
S
T
K
N
Site 111
S1456
P
G
P
S
T
G
P
S
T
K
N
E
N
V
A
Site 112
T1464
T
K
N
E
N
V
A
T
L
S
V
S
S
L
E
Site 113
S1466
N
E
N
V
A
T
L
S
V
S
S
L
E
R
R
Site 114
S1468
N
V
A
T
L
S
V
S
S
L
E
R
R
K
S
Site 115
S1469
V
A
T
L
S
V
S
S
L
E
R
R
K
S
R
Site 116
S1475
S
S
L
E
R
R
K
S
R
Y
A
E
L
D
F
Site 117
Y1477
L
E
R
R
K
S
R
Y
A
E
L
D
F
E
K
Site 118
S1518
K
E
V
L
G
P
D
S
K
P
E
K
Q
Q
T
Site 119
T1525
S
K
P
E
K
Q
Q
T
P
N
K
R
P
W
E
Site 120
S1533
P
N
K
R
P
W
E
S
L
R
K
A
H
G
T
Site 121
T1540
S
L
R
K
A
H
G
T
P
T
W
V
K
K
E
Site 122
S1554
E
L
E
P
L
Q
P
S
P
L
E
L
R
S
V
Site 123
S1560
P
S
P
L
E
L
R
S
V
E
W
E
R
S
G
Site 124
S1566
R
S
V
E
W
E
R
S
G
A
T
I
P
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation