KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
DPYSL4
Full Name:
Dihydropyrimidinase-related protein 4
Alias:
Collapsin response mediator 3; CRMP-3; Dihydropyrimidinase-like 4; Dihydropyrimidinase-related 4; DPYL4; DRP-4; ULIP4; UNC33-like phosphoprotein 4
Type:
Unknown function
Mass (Da):
61878
Number AA:
572
UniProt ID:
O14531
International Prot ID:
IPI00022388
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0016810
PhosphoSite+
KinaseNET
Biological Process:
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
F
Q
G
K
K
S
I
P
R
I
T
S
D
Site 2
T13
K
K
S
I
P
R
I
T
S
D
R
L
L
I
R
Site 3
S14
K
S
I
P
R
I
T
S
D
R
L
L
I
R
G
Site 4
Y32
V
N
D
D
Q
S
F
Y
A
D
V
H
V
E
D
Site 5
S147
D
I
T
R
W
H
E
S
I
K
E
E
L
E
A
Site 6
Y182
Q
C
S
D
S
Q
M
Y
E
I
F
S
I
I
R
Site 7
S226
G
P
E
G
H
V
L
S
H
P
E
E
V
E
A
Site 8
Y251
K
Q
A
N
C
P
L
Y
V
T
K
V
M
S
K
Site 9
S282
F
G
E
P
I
T
A
S
L
G
T
D
G
S
H
Site 10
Y290
L
G
T
D
G
S
H
Y
W
S
K
N
W
A
K
Site 11
S304
K
A
A
A
F
V
T
S
P
P
V
N
P
D
P
Site 12
T312
P
P
V
N
P
D
P
T
T
A
D
H
L
T
C
Site 13
T313
P
V
N
P
D
P
T
T
A
D
H
L
T
C
L
Site 14
T318
P
T
T
A
D
H
L
T
C
L
L
S
S
G
D
Site 15
S331
G
D
L
Q
V
T
G
S
A
H
C
T
F
T
T
Site 16
T335
V
T
G
S
A
H
C
T
F
T
T
A
Q
K
A
Site 17
Y395
A
A
K
I
F
N
F
Y
P
R
K
G
R
V
A
Site 18
S421
P
K
A
T
K
I
I
S
A
K
T
H
N
L
N
Site 19
Y431
T
H
N
L
N
V
E
Y
N
I
F
E
G
V
E
Site 20
T462
E
D
G
K
M
F
V
T
P
G
A
G
R
F
V
Site 21
T473
G
R
F
V
P
R
K
T
F
P
D
F
V
Y
K
Site 22
Y479
K
T
F
P
D
F
V
Y
K
R
I
K
A
R
N
Site 23
Y499
H
G
V
P
R
G
L
Y
D
G
P
V
H
E
V
Site 24
S514
M
V
P
A
K
P
G
S
G
A
P
A
R
A
S
Site 25
S521
S
G
A
P
A
R
A
S
C
P
G
K
I
S
V
Site 26
S527
A
S
C
P
G
K
I
S
V
P
P
V
R
N
L
Site 27
S537
P
V
R
N
L
H
Q
S
G
F
S
L
S
G
S
Site 28
S540
N
L
H
Q
S
G
F
S
L
S
G
S
Q
A
D
Site 29
S542
H
Q
S
G
F
S
L
S
G
S
Q
A
D
D
H
Site 30
S544
S
G
F
S
L
S
G
S
Q
A
D
D
H
I
A
Site 31
T554
D
D
H
I
A
R
R
T
A
Q
K
I
M
A
P
Site 32
S566
M
A
P
P
G
G
R
S
N
I
T
S
L
S
_
Site 33
S570
G
G
R
S
N
I
T
S
L
S
_
_
_
_
_
Site 34
S572
R
S
N
I
T
S
L
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation