KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FLN29
Full Name:
TRAF-type zinc finger domain-containing protein 1
Alias:
Protein FLN29
Type:
DNA binding protein
Mass (Da):
64841
Number AA:
582
UniProt ID:
O14545
International Prot ID:
IPI00009146
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T53
F
P
K
S
D
M
E
T
H
M
A
A
E
H
C
Site 2
T81
L
L
K
K
H
E
E
T
E
C
P
L
R
L
A
Site 3
S98
Q
H
C
D
L
E
L
S
I
L
K
L
K
E
H
Site 4
Y108
K
L
K
E
H
E
D
Y
C
G
A
R
T
E
L
Site 5
T130
V
L
V
K
D
L
K
T
H
P
E
V
C
G
R
Site 6
Y153
V
A
I
P
P
N
A
Y
D
E
S
W
G
Q
D
Site 7
S166
Q
D
G
I
W
I
A
S
Q
L
L
R
Q
I
E
Site 8
S191
R
P
L
R
A
F
E
S
D
V
F
H
N
R
T
Site 9
T205
T
T
N
Q
R
N
I
T
A
Q
V
S
I
Q
N
Site 10
S256
Q
N
E
G
Q
A
S
S
V
A
E
Q
D
F
W
Site 11
S272
A
V
C
E
A
D
Q
S
H
G
G
P
R
S
L
Site 12
S278
Q
S
H
G
G
P
R
S
L
S
D
I
K
G
A
Site 13
S280
H
G
G
P
R
S
L
S
D
I
K
G
A
A
D
Site 14
Y300
C
E
F
C
E
E
L
Y
P
E
E
L
L
I
D
Site 15
T310
E
L
L
I
D
H
Q
T
S
C
N
P
S
R
A
Site 16
S311
L
L
I
D
H
Q
T
S
C
N
P
S
R
A
L
Site 17
S315
H
Q
T
S
C
N
P
S
R
A
L
P
S
L
N
Site 18
S320
N
P
S
R
A
L
P
S
L
N
T
G
S
S
S
Site 19
T323
R
A
L
P
S
L
N
T
G
S
S
S
P
R
G
Site 20
S325
L
P
S
L
N
T
G
S
S
S
P
R
G
V
E
Site 21
S326
P
S
L
N
T
G
S
S
S
P
R
G
V
E
E
Site 22
S327
S
L
N
T
G
S
S
S
P
R
G
V
E
E
P
Site 23
S347
N
F
L
Q
Q
A
A
S
N
Q
L
D
S
L
M
Site 24
S352
A
A
S
N
Q
L
D
S
L
M
G
L
S
N
S
Site 25
S357
L
D
S
L
M
G
L
S
N
S
H
P
V
E
E
Site 26
S359
S
L
M
G
L
S
N
S
H
P
V
E
E
S
I
Site 27
T395
Q
C
D
Q
R
P
A
T
A
T
N
H
V
T
E
Site 28
T397
D
Q
R
P
A
T
A
T
N
H
V
T
E
G
I
Site 29
S409
E
G
I
P
R
L
D
S
Q
P
Q
E
T
S
P
Site 30
T414
L
D
S
Q
P
Q
E
T
S
P
E
L
P
R
R
Site 31
S415
D
S
Q
P
Q
E
T
S
P
E
L
P
R
R
R
Site 32
S430
V
R
H
Q
G
D
L
S
S
G
Y
L
D
D
T
Site 33
S431
R
H
Q
G
D
L
S
S
G
Y
L
D
D
T
K
Site 34
Y433
Q
G
D
L
S
S
G
Y
L
D
D
T
K
Q
E
Site 35
T437
S
S
G
Y
L
D
D
T
K
Q
E
T
A
N
G
Site 36
S447
E
T
A
N
G
P
T
S
C
L
P
P
S
R
P
Site 37
S452
P
T
S
C
L
P
P
S
R
P
I
N
N
M
T
Site 38
T461
P
I
N
N
M
T
A
T
Y
N
Q
L
S
R
S
Site 39
S466
T
A
T
Y
N
Q
L
S
R
S
T
S
G
P
R
Site 40
S468
T
Y
N
Q
L
S
R
S
T
S
G
P
R
P
G
Site 41
T469
Y
N
Q
L
S
R
S
T
S
G
P
R
P
G
C
Site 42
S470
N
Q
L
S
R
S
T
S
G
P
R
P
G
C
Q
Site 43
S479
P
R
P
G
C
Q
P
S
S
P
C
V
P
K
L
Site 44
S480
R
P
G
C
Q
P
S
S
P
C
V
P
K
L
S
Site 45
S487
S
P
C
V
P
K
L
S
N
S
D
S
Q
D
I
Site 46
S489
C
V
P
K
L
S
N
S
D
S
Q
D
I
Q
G
Site 47
S491
P
K
L
S
N
S
D
S
Q
D
I
Q
G
R
N
Site 48
S501
I
Q
G
R
N
R
D
S
Q
N
G
A
I
A
P
Site 49
S512
A
I
A
P
G
H
V
S
V
I
R
P
P
Q
N
Site 50
Y521
I
R
P
P
Q
N
L
Y
P
E
N
I
V
P
S
Site 51
S528
Y
P
E
N
I
V
P
S
F
S
P
G
P
S
G
Site 52
S530
E
N
I
V
P
S
F
S
P
G
P
S
G
R
Y
Site 53
S534
P
S
F
S
P
G
P
S
G
R
Y
G
A
S
G
Site 54
Y537
S
P
G
P
S
G
R
Y
G
A
S
G
R
S
E
Site 55
S540
P
S
G
R
Y
G
A
S
G
R
S
E
G
G
R
Site 56
S549
R
S
E
G
G
R
N
S
R
V
T
P
A
A
A
Site 57
T552
G
G
R
N
S
R
V
T
P
A
A
A
N
Y
R
Site 58
Y558
V
T
P
A
A
A
N
Y
R
S
R
T
A
K
A
Site 59
T562
A
A
N
Y
R
S
R
T
A
K
A
K
P
S
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation