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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
COPE
Full Name:
Coatomer subunit epsilon
Alias:
Coatomer epsilon; Coatomer protein complex, subunit epsilon; Epsilon-coat protein; Epsilon-COP
Type:
Vesicle protein
Mass (Da):
34482
Number AA:
308
UniProt ID:
O14579
International Prot ID:
IPI00465132
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030126
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0048205
GO:0006891
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
P
P
A
P
G
P
A
S
G
G
S
G
E
V
D
Site 2
S13
P
G
P
A
S
G
G
S
G
E
V
D
E
L
F
Site 3
S44
A
Q
R
V
K
L
S
S
P
E
R
D
V
E
R
Site 4
S45
A
Q
R
V
K
L
S
S
P
E
R
D
V
E
R
Site 5
Y57
V
E
R
D
V
F
L
Y
R
A
Y
L
A
Q
R
Site 6
Y60
D
V
F
L
Y
R
A
Y
L
A
Q
R
K
F
G
Site 7
S76
V
L
D
E
I
K
P
S
S
A
P
E
L
Q
A
Site 8
S77
L
D
E
I
K
P
S
S
A
P
E
L
Q
A
V
Site 9
Y90
A
V
R
M
F
A
D
Y
L
A
H
E
S
R
R
Site 10
S95
A
D
Y
L
A
H
E
S
R
R
D
S
I
V
A
Site 11
S99
A
H
E
S
R
R
D
S
I
V
A
E
L
D
R
Site 12
S109
A
E
L
D
R
E
M
S
R
S
V
D
V
T
N
Site 13
S111
L
D
R
E
M
S
R
S
V
D
V
T
N
T
T
Site 14
Y127
L
L
M
A
A
S
I
Y
L
H
D
Q
N
P
D
Site 15
S145
R
A
L
H
Q
G
D
S
L
E
C
T
A
M
T
Site 16
T180
Q
D
L
D
E
D
A
T
L
T
Q
L
A
T
A
Site 17
Y202
G
E
K
L
Q
D
A
Y
Y
I
F
Q
E
M
A
Site 18
Y203
E
K
L
Q
D
A
Y
Y
I
F
Q
E
M
A
D
Site 19
S213
Q
E
M
A
D
K
C
S
P
T
L
L
L
L
N
Site 20
S247
Q
E
A
L
D
K
D
S
G
Y
P
E
T
L
V
Site 21
Y249
A
L
D
K
D
S
G
Y
P
E
T
L
V
N
L
Site 22
T270
L
G
K
P
P
E
V
T
N
R
Y
L
S
Q
L
Site 23
Y273
P
P
E
V
T
N
R
Y
L
S
Q
L
K
D
A
Site 24
S275
E
V
T
N
R
Y
L
S
Q
L
K
D
A
H
R
Site 25
Y290
S
H
P
F
I
K
E
Y
Q
A
K
E
N
D
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation