PhosphoNET

           
Protein Info 
   
Short Name:  CDC42EP2
Full Name:  Cdc42 effector protein 2
Alias:  Binder of Rho GTPases 1; BORG1; Cdc42 effector 2; CDC42 effector protein (Rho GTPase binding) 2; CEP2; CRIB-containing BOGR1
Type:  Adaptor/scaffold protein
Mass (Da):  22484
Number AA:  210
UniProt ID:  O14613
International Prot ID:  IPI00009533
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005856  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0017049  GO:0005100   PhosphoSite+ KinaseNET
Biological Process:  GO:0007015  GO:0030838  GO:0031274 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y8MSTKVPIYLKRGSRK
Site 2S13PIYLKRGSRKGKKEK
Site 3S26EKLRDLLSSDMISPP
Site 4S27KLRDLLSSDMISPPL
Site 5S31LLSSDMISPPLGDFR
Site 6T40PLGDFRHTIHIGSGG
Site 7S45RHTIHIGSGGGSDMF
Site 8S49HIGSGGGSDMFGDIS
Site 9S56SDMFGDISFLQGKFH
Site 10T68KFHLLPGTMVEGPEE
Site 11T78EGPEEDGTFDLPFQF
Site 12T88LPFQFTRTATVCGRE
Site 13T90FQFTRTATVCGRELP
Site 14S101RELPDGPSPLLKNAI
Site 15T137PPRLHLETPQPSPQE
Site 16S141HLETPQPSPQEGGSV
Site 17T156DIWRIPETGSPNSGL
Site 18S158WRIPETGSPNSGLTP
Site 19S161PETGSPNSGLTPESG
Site 20T164GSPNSGLTPESGAEE
Site 21S167NSGLTPESGAEEPFL
Site 22S175GAEEPFLSNASSLLS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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