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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AP3D1
Full Name:
AP-3 complex subunit delta-1
Alias:
Adapter-related protein complex 3 delta-1; Adaptor-related protein complex 3, delta 1 subunit; ADTD; AP-3 complex delta; Delta-adaptin 3
Type:
Golgi membrane, Membrane, Membrane coat, Golgi apparatus protein
Mass (Da):
130158
Number AA:
1153
UniProt ID:
O14617
International Prot ID:
IPI00411453
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0030117
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006726
GO:0006886
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
L
K
M
V
K
G
S
I
D
R
M
F
D
K
Site 2
Y35
H
K
E
D
E
A
K
Y
I
S
Q
C
I
D
E
Site 3
S37
E
D
E
A
K
Y
I
S
Q
C
I
D
E
I
K
Site 4
S99
R
I
G
Y
L
A
A
S
Q
S
F
H
E
G
T
Site 5
S101
G
Y
L
A
A
S
Q
S
F
H
E
G
T
D
V
Site 6
T112
G
T
D
V
I
M
L
T
T
N
Q
I
R
K
D
Site 7
S121
N
Q
I
R
K
D
L
S
S
P
S
Q
Y
D
T
Site 8
S122
Q
I
R
K
D
L
S
S
P
S
Q
Y
D
T
G
Site 9
S124
R
K
D
L
S
S
P
S
Q
Y
D
T
G
V
A
Site 10
Y126
D
L
S
S
P
S
Q
Y
D
T
G
V
A
L
T
Site 11
T128
S
S
P
S
Q
Y
D
T
G
V
A
L
T
G
L
Site 12
T153
D
L
A
N
D
I
M
T
L
M
S
H
T
K
P
Site 13
Y161
L
M
S
H
T
K
P
Y
I
R
K
K
A
V
L
Site 14
Y177
M
Y
K
V
F
L
K
Y
P
E
S
L
R
P
A
Site 15
S180
V
F
L
K
Y
P
E
S
L
R
P
A
F
P
R
Site 16
Y218
A
R
R
N
P
K
N
Y
L
S
L
A
P
L
F
Site 17
S220
R
N
P
K
N
Y
L
S
L
A
P
L
F
F
K
Site 18
T264
K
K
L
I
E
P
L
T
N
L
I
H
S
T
S
Site 19
S298
S
S
G
M
P
N
H
S
A
S
I
Q
L
C
V
Site 20
S300
G
M
P
N
H
S
A
S
I
Q
L
C
V
Q
K
Site 21
S315
L
R
I
L
I
E
D
S
D
Q
N
L
K
Y
L
Site 22
Y321
D
S
D
Q
N
L
K
Y
L
G
L
L
A
M
S
Site 23
T333
A
M
S
K
I
L
K
T
H
P
K
S
V
Q
S
Site 24
S337
I
L
K
T
H
P
K
S
V
Q
S
H
K
D
L
Site 25
S355
C
L
D
D
K
D
E
S
I
R
L
R
A
L
D
Site 26
Y365
L
R
A
L
D
L
L
Y
G
M
V
S
K
K
N
Site 27
Y392
D
K
A
E
G
T
T
Y
R
D
E
L
L
T
K
Site 28
T398
T
Y
R
D
E
L
L
T
K
I
I
D
I
C
S
Site 29
Y409
D
I
C
S
Q
S
N
Y
Q
Y
I
T
N
F
E
Site 30
S472
S
A
H
L
L
A
S
S
T
Q
R
N
G
I
C
Site 31
T473
A
H
L
L
A
S
S
T
Q
R
N
G
I
C
E
Site 32
T502
H
L
Q
E
P
H
H
T
L
E
A
M
L
R
P
Site 33
T512
A
M
L
R
P
R
V
T
T
L
P
G
H
I
Q
Site 34
T513
M
L
R
P
R
V
T
T
L
P
G
H
I
Q
A
Site 35
S632
A
W
I
N
E
P
L
S
D
S
E
S
E
D
E
Site 36
S634
I
N
E
P
L
S
D
S
E
S
E
D
E
R
P
Site 37
S636
E
P
L
S
D
S
E
S
E
D
E
R
P
R
A
Site 38
S658
R
R
P
K
H
R
P
S
E
A
D
E
E
E
L
Site 39
Y682
E
Q
A
N
N
P
F
Y
I
K
S
S
P
S
P
Site 40
S685
N
N
P
F
Y
I
K
S
S
P
S
P
Q
K
R
Site 41
S686
N
P
F
Y
I
K
S
S
P
S
P
Q
K
R
Y
Site 42
S688
F
Y
I
K
S
S
P
S
P
Q
K
R
Y
Q
D
Site 43
T696
P
Q
K
R
Y
Q
D
T
P
G
V
E
H
I
P
Site 44
S721
K
V
P
G
L
P
M
S
D
Q
Y
V
K
L
E
Site 45
Y724
G
L
P
M
S
D
Q
Y
V
K
L
E
E
E
R
Site 46
S758
K
K
G
K
R
R
H
S
S
L
P
T
E
S
D
Site 47
S759
K
G
K
R
R
H
S
S
L
P
T
E
S
D
E
Site 48
T762
R
R
H
S
S
L
P
T
E
S
D
E
D
I
A
Site 49
S764
H
S
S
L
P
T
E
S
D
E
D
I
A
P
A
Site 50
T778
A
Q
Q
V
D
I
V
T
E
E
M
P
E
N
A
Site 51
S788
M
P
E
N
A
L
P
S
D
E
D
D
K
D
P
Site 52
Y799
D
K
D
P
N
D
P
Y
R
A
L
D
I
D
L
Site 53
T824
P
I
Q
K
H
R
N
T
E
T
S
K
S
P
E
Site 54
T826
Q
K
H
R
N
T
E
T
S
K
S
P
E
K
D
Site 55
S827
K
H
R
N
T
E
T
S
K
S
P
E
K
D
V
Site 56
S829
R
N
T
E
T
S
K
S
P
E
K
D
V
P
M
Site 57
S869
K
E
K
E
K
K
K
S
P
K
P
K
K
K
K
Site 58
S891
R
T
K
G
K
K
K
S
K
K
Q
P
P
G
S
Site 59
S898
S
K
K
Q
P
P
G
S
E
E
A
A
G
E
P
Site 60
S920
E
E
Q
L
P
P
E
S
S
Y
S
L
L
A
E
Site 61
S921
E
Q
L
P
P
E
S
S
Y
S
L
L
A
E
N
Site 62
S923
L
P
P
E
S
S
Y
S
L
L
A
E
N
S
Y
Site 63
S929
Y
S
L
L
A
E
N
S
Y
V
K
M
T
C
D
Site 64
S940
M
T
C
D
I
R
G
S
L
Q
E
D
S
Q
V
Site 65
S945
R
G
S
L
Q
E
D
S
Q
V
T
V
A
I
V
Site 66
S958
I
V
L
E
N
R
S
S
S
I
L
K
G
M
E
Site 67
S959
V
L
E
N
R
S
S
S
I
L
K
G
M
E
L
Site 68
S971
M
E
L
S
V
L
D
S
L
N
A
R
M
A
R
Site 69
S982
R
M
A
R
P
Q
G
S
S
V
H
D
G
V
P
Site 70
S983
M
A
R
P
Q
G
S
S
V
H
D
G
V
P
V
Site 71
S1022
Q
K
L
K
G
T
L
S
F
I
A
K
N
D
E
Site 72
T1050
S
C
S
S
Y
L
I
T
T
P
C
Y
S
D
A
Site 73
S1071
S
G
D
L
S
M
S
S
I
K
V
D
G
I
R
Site 74
S1080
K
V
D
G
I
R
M
S
F
Q
N
L
L
A
K
Site 75
S1102
S
V
V
E
R
V
D
S
C
A
S
M
Y
S
R
Site 76
S1105
E
R
V
D
S
C
A
S
M
Y
S
R
S
I
Q
Site 77
Y1107
V
D
S
C
A
S
M
Y
S
R
S
I
Q
G
H
Site 78
S1108
D
S
C
A
S
M
Y
S
R
S
I
Q
G
H
H
Site 79
S1126
L
V
K
K
G
E
N
S
V
S
V
D
G
K
C
Site 80
S1128
K
K
G
E
N
S
V
S
V
D
G
K
C
S
D
Site 81
S1134
V
S
V
D
G
K
C
S
D
S
T
L
L
S
N
Site 82
T1137
D
G
K
C
S
D
S
T
L
L
S
N
L
L
E
Site 83
S1140
C
S
D
S
T
L
L
S
N
L
L
E
E
M
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation