PhosphoNET

           
Protein Info 
   
Short Name:  DVL2
Full Name:  Segment polarity protein dishevelled homolog DVL-2
Alias:  Dishevelled 2; Dishevelled 2 (homologous to Drosophila dsh); Dishevelled, dsh 2; Dishevelled, dsh homolog 2 (Drosophila); Dishevelled-2; DSH homolog 2; Segment polarity protein dishevelled homolog DVL-2
Type:  Adaptor/scaffold
Mass (Da):  78948
Number AA:  736
UniProt ID:  O14641
International Prot ID:  IPI00023103
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0042802  GO:0004871   PhosphoSite+ KinaseNET
Biological Process:  GO:0016055  GO:0007507  GO:0007447 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y18VGETKVIYHLDEEET
Site 2T25YHLDEEETPYLVKIP
Site 3Y27LDEEETPYLVKIPVP
Site 4T39PVPAERITLGDFKSV
Site 5Y55QRPAGAKYFFKSMDQ
Site 6S91RVVSWLVSSDNPQPE
Site 7S92VVSWLVSSDNPQPEM
Site 8S126PLPPERTSGIGDSRP
Site 9S131RTSGIGDSRPPSFHP
Site 10S135IGDSRPPSFHPNVSS
Site 11S141PSFHPNVSSSHENLE
Site 12S142SFHPNVSSSHENLEP
Site 13S143FHPNVSSSHENLEPE
Site 14T151HENLEPETETESVVS
Site 15T153NLEPETETESVVSLR
Site 16S155EPETETESVVSLRRE
Site 17S158TETESVVSLRRERPR
Site 18S169ERPRRRDSSEHGAGG
Site 19S170RPRRRDSSEHGAGGH
Site 20T179HGAGGHRTGGPSRLE
Site 21S183GHRTGGPSRLERHLA
Site 22Y192LERHLAGYESSSTLM
Site 23S194RHLAGYESSSTLMTS
Site 24S195HLAGYESSSTLMTSE
Site 25S196LAGYESSSTLMTSEL
Site 26T197AGYESSSTLMTSELE
Site 27T200ESSSTLMTSELESTS
Site 28S201SSSTLMTSELESTSL
Site 29S205LMTSELESTSLGDSD
Site 30T206MTSELESTSLGDSDE
Site 31S207TSELESTSLGDSDEE
Site 32S211ESTSLGDSDEEDTMS
Site 33T216GDSDEEDTMSRFSSS
Site 34S218SDEEDTMSRFSSSTE
Site 35S221EDTMSRFSSSTEQSS
Site 36S222DTMSRFSSSTEQSSA
Site 37S223TMSRFSSSTEQSSAS
Site 38T224MSRFSSSTEQSSASR
Site 39S227FSSSTEQSSASRLLK
Site 40S228SSSTEQSSASRLLKR
Site 41T250RPPRLERTSSFSSVT
Site 42S251PPRLERTSSFSSVTD
Site 43S252PRLERTSSFSSVTDS
Site 44S254LERTSSFSSVTDSTM
Site 45S255ERTSSFSSVTDSTMS
Site 46Y275VTLNMEKYNFLGISI
Site 47S286GISIVGQSNERGDGG
Site 48Y295ERGDGGIYIGSIMKG
Site 49Y362WDPSPQAYFTLPRNE
Site 50T364PSPQAYFTLPRNEPI
Site 51T389HSAALTGTFPAYPGS
Site 52Y393LTGTFPAYPGSSSMS
Site 53S396TFPAYPGSSSMSTIT
Site 54S398PAYPGSSSMSTITSG
Site 55S400YPGSSSMSTITSGSS
Site 56T401PGSSSMSTITSGSSL
Site 57T403SSSMSTITSGSSLPD
Site 58S404SSMSTITSGSSLPDG
Site 59S406MSTITSGSSLPDGCE
Site 60S407STITSGSSLPDGCEG
Site 61S418GCEGRGLSVHTDMAS
Site 62Y463SDVVDWLYHHVEGFP
Site 63Y478ERREARKYASGLLKA
Site 64T491KAGLIRHTVNKITFS
Site 65Y503TFSEQCYYVFGDLSG
Site 66S520ESYLVNLSLNDNDGS
Site 67S527SLNDNDGSSGASDQD
Site 68S528LNDNDGSSGASDQDT
Site 69S531NDGSSGASDQDTLAP
Site 70T535SGASDQDTLAPLPGA
Site 71T550TPWPLLPTFSYQYPA
Site 72Y553PLLPTFSYQYPAPHP
Site 73Y555LPTFSYQYPAPHPYS
Site 74Y561QYPAPHPYSPQPPPY
Site 75S562YPAPHPYSPQPPPYH
Site 76Y568YSPQPPPYHELSSYT
Site 77S572PPPYHELSSYTYGGG
Site 78S573PPYHELSSYTYGGGS
Site 79Y574PYHELSSYTYGGGSA
Site 80Y576HELSSYTYGGGSASS
Site 81S580SYTYGGGSASSQHSE
Site 82S582TYGGGSASSQHSEGS
Site 83S583YGGGSASSQHSEGSR
Site 84S586GSASSQHSEGSRSSG
Site 85S589SSQHSEGSRSSGSTR
Site 86S591QHSEGSRSSGSTRSD
Site 87S592HSEGSRSSGSTRSDG
Site 88S594EGSRSSGSTRSDGGA
Site 89T595GSRSSGSTRSDGGAG
Site 90S597RSSGSTRSDGGAGRT
Site 91T604SDGGAGRTGRPEERA
Site 92S614PEERAPESKSGSGSE
Site 93S616ERAPESKSGSGSESE
Site 94S618APESKSGSGSESEPS
Site 95S620ESKSGSGSESEPSSR
Site 96S622KSGSGSESEPSSRGG
Site 97S625SGSESEPSSRGGSLR
Site 98S626GSESEPSSRGGSLRR
Site 99S630EPSSRGGSLRRGGEA
Site 100S638LRRGGEASGTSDGGP
Site 101T640RGGEASGTSDGGPPP
Site 102S641GGEASGTSDGGPPPS
Site 103S648SDGGPPPSRGSTGGA
Site 104S651GPPPSRGSTGGAPNL
Site 105T652PPPSRGSTGGAPNLR
Site 106Y667AHPGLHPYGPPPGMA
Site 107S709PPVRDLGSVPPELTA
Site 108T715GSVPPELTASRQSFH
Site 109S717VPPELTASRQSFHMA
Site 110S720ELTASRQSFHMAMGN
Site 111S729HMAMGNPSEFFVDVM
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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