PhosphoNET

           
Protein Info 
   
Short Name:  CHD1
Full Name:  Chromodomain-helicase-DNA-binding protein 1
Alias:  ATP-dependent helicase CHD1; EC 3.6.1.-
Type:  EC 3.6.1.-; Helicase
Mass (Da):  196688
Number AA:  1710
UniProt ID:  O14646
International Prot ID:  IPI00297851
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000785  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0004003  GO:0003677 PhosphoSite+ KinaseNET
Biological Process:  GO:0006333  GO:0006357  GO:0051276 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S5___MNGHSDEESVRN
Site 2S9NGHSDEESVRNSSGE
Site 3S13DEESVRNSSGESSQS
Site 4S14EESVRNSSGESSQSD
Site 5S17VRNSSGESSQSDDDS
Site 6S18RNSSGESSQSDDDSG
Site 7S20SSGESSQSDDDSGSA
Site 8S24SSQSDDDSGSASGSG
Site 9S26QSDDDSGSASGSGSG
Site 10S28DDDSGSASGSGSGSS
Site 11S30DSGSASGSGSGSSSG
Site 12S32GSASGSGSGSSSGSS
Site 13S34ASGSGSGSSSGSSSD
Site 14S35SGSGSGSSSGSSSDG
Site 15S36GSGSGSSSGSSSDGS
Site 16S38GSGSSSGSSSDGSSS
Site 17S39SGSSSGSSSDGSSSQ
Site 18S40GSSSGSSSDGSSSQS
Site 19S43SGSSSDGSSSQSGSS
Site 20S44GSSSDGSSSQSGSSD
Site 21S45SSSDGSSSQSGSSDS
Site 22S47SDGSSSQSGSSDSDS
Site 23S49GSSSQSGSSDSDSGS
Site 24S50SSSQSGSSDSDSGSE
Site 25S52SQSGSSDSDSGSESG
Site 26S54SGSSDSDSGSESGSQ
Site 27S56SSDSDSGSESGSQSE
Site 28S58DSDSGSESGSQSESE
Site 29S60DSGSESGSQSESESD
Site 30S62GSESGSQSESESDTS
Site 31S64ESGSQSESESDTSRE
Site 32S66GSQSESESDTSRENK
Site 33T68QSESESDTSRENKVQ
Site 34S69SESESDTSRENKVQA
Site 35S89DGAEFWKSSPSILAV
Site 36S90GAEFWKSSPSILAVQ
Site 37S92EFWKSSPSILAVQRS
Site 38S99SILAVQRSAILKKQQ
Site 39S118QQQHQASSNSGSEED
Site 40S120QHQASSNSGSEEDSS
Site 41S122QASSNSGSEEDSSSS
Site 42S126NSGSEEDSSSSEDSD
Site 43S127SGSEEDSSSSEDSDD
Site 44S128GSEEDSSSSEDSDDS
Site 45S129SEEDSSSSEDSDDSS
Site 46S132DSSSSEDSDDSSSEV
Site 47S135SSEDSDDSSSEVKRK
Site 48S136SEDSDDSSSEVKRKK
Site 49S137EDSDDSSSEVKRKKH
Site 50S152KDEDWQMSGSGSPSQ
Site 51S154EDWQMSGSGSPSQSG
Site 52S156WQMSGSGSPSQSGSD
Site 53S158MSGSGSPSQSGSDSE
Site 54S160GSGSPSQSGSDSESE
Site 55S162GSPSQSGSDSESEEE
Site 56S164PSQSGSDSESEEERE
Site 57S166QSGSDSESEEEREKS
Site 58S173SEEEREKSSCDETES
Site 59S174EEEREKSSCDETESD
Site 60T178EKSSCDETESDYEPK
Site 61S180SSCDETESDYEPKNK
Site 62Y182CDETESDYEPKNKVK
Site 63S190EPKNKVKSRKPQNRS
Site 64S197SRKPQNRSKSKNGKK
Site 65S199KPQNRSKSKNGKKIL
Site 66S215QKKRQIDSSEEDDDE
Site 67S216KKRQIDSSEEDDDEE
Site 68Y225EDDDEEDYDNDKRSS
Site 69S231DYDNDKRSSRRQATV
Site 70S232YDNDKRSSRRQATVN
Site 71T237RSSRRQATVNVSYKE
Site 72S241RQATVNVSYKEDEEM
Site 73T250KEDEEMKTDSDDLLE
Site 74S252DEEMKTDSDDLLEVC
Site 75T273PEEEEFETIERFMDC
Site 76Y295TGATTTIYAVEADGD
Site 77Y318KEPGEIQYLIKWKGW
Site 78T337NTWETEETLKQQNVR
Site 79Y352GMKKLDNYKKKDQET
Site 80T359YKKKDQETKRWLKNA
Site 81S367KRWLKNASPEDVEYY
Site 82Y373ASPEDVEYYNCQQEL
Site 83Y374SPEDVEYYNCQQELT
Site 84Y388TDDLHKQYQIVGRII
Site 85S398VGRIIAHSNQKSAAG
Site 86S402IAHSNQKSAAGYPDY
Site 87Y406NQKSAAGYPDYYCKW
Site 88Y409SAAGYPDYYCKWQGL
Site 89Y410AAGYPDYYCKWQGLP
Site 90Y440FQACIDEYFSRNQSK
Site 91S446EYFSRNQSKTTPFKD
Site 92T448FSRNQSKTTPFKDCK
Site 93T449SRNQSKTTPFKDCKV
Site 94S471VALKKQPSYIGGHEG
Site 95Y472ALKKQPSYIGGHEGL
Site 96Y484EGLELRDYQLNGLNW
Site 97Y522QTISFLNYLFHEHQL
Site 98S544VPLSTLTSWQREIQT
Site 99Y561SQMNAVVYLGDINSR
Site 100S624HRLKNDDSLLYKTLI
Site 101Y627KNDDSLLYKTLIDFK
Site 102T629DDSLLYKTLIDFKSN
Site 103S635KTLIDFKSNHRLLIT
Site 104T642SNHRLLITGTPLQNS
Site 105T644HRLLITGTPLQNSLK
Site 106S649TGTPLQNSLKELWSL
Site 107S667IMPEKFSSWEDFEEE
Site 108Y681EHGKGREYGYASLHK
Site 109S685GREYGYASLHKELEP
Site 110S705VKKDVEKSLPAKVEQ
Site 111S719QILRMEMSALQKQYY
Site 112Y726SALQKQYYKWILTRN
Site 113Y734KWILTRNYKALSKGS
Site 114S738TRNYKALSKGSKGST
Site 115S744LSKGSKGSTSGFLNI
Site 116T745SKGSKGSTSGFLNIM
Site 117S746KGSKGSTSGFLNIMM
Site 118Y774PPDNNEFYNKQEALQ
Site 119Y823MLDILAEYLKYRQFP
Site 120Y826ILAEYLKYRQFPFQR
Site 121S837PFQRLDGSIKGELRK
Site 122T914VNIYRLVTKGSVEED
Site 123S917YRLVTKGSVEEDILE
Site 124T946RMDTTGKTVLHTGSA
Site 125T950TGKTVLHTGSAPSSS
Site 126S952KTVLHTGSAPSSSTP
Site 127S956HTGSAPSSSTPFNKE
Site 128S957TGSAPSSSTPFNKEE
Site 129T958GSAPSSSTPFNKEEL
Site 130T1001EILKRAETHENEPGP
Site 131T1010ENEPGPLTVGDELLS
Site 132S1025QFKVANFSNMDEDDI
Site 133S1040ELEPERNSKNWEEII
Site 134Y1068QKELEEIYMLPRMRN
Site 135S1081RNCAKQISFNGSEGR
Site 136S1085KQISFNGSEGRRSRS
Site 137S1090NGSEGRRSRSRRYSG
Site 138S1092SEGRRSRSRRYSGSD
Site 139Y1095RRSRSRRYSGSDSDS
Site 140S1096RSRSRRYSGSDSDSI
Site 141S1098RSRRYSGSDSDSISE
Site 142S1100RRYSGSDSDSISEGK
Site 143S1102YSGSDSDSISEGKRP
Site 144S1104GSDSDSISEGKRPKK
Site 145T1117KKRGRPRTIPRENIK
Site 146S1127RENIKGFSDAEIRRF
Site 147S1137EIRRFIKSYKKFGGP
Site 148Y1138IRRFIKSYKKFGGPL
Site 149S1161DAELVDKSETDLRRL
Site 150S1183CIKALKDSSSGTERT
Site 151S1184IKALKDSSSGTERTG
Site 152S1185KALKDSSSGTERTGG
Site 153T1187LKDSSSGTERTGGRL
Site 154T1201LGKVKGPTFRISGVQ
Site 155S1205KGPTFRISGVQVNAK
Site 156S1227ELIPLHKSIPSDPEE
Site 157S1230PLHKSIPSDPEERKQ
Site 158Y1238DPEERKQYTIPCHTK
Site 159Y1266SNLLIGIYEYGYGSW
Site 160Y1270IGIYEYGYGSWEMIK
Site 161S1283IKMDPDLSLTHKILP
Site 162T1285MDPDLSLTHKILPDD
Site 163Y1308QLQTRADYLIKLLSR
Site 164S1324LAKKEALSGAGSSKR
Site 165S1328EALSGAGSSKRRKAR
Site 166S1329ALSGAGSSKRRKARA
Site 167S1344KKNKAMKSIKVKEEI
Site 168S1353KVKEEIKSDSSPLPS
Site 169S1355KEEIKSDSSPLPSEK
Site 170S1356EEIKSDSSPLPSEKS
Site 171S1360SDSSPLPSEKSDEDD
Site 172S1363SPLPSEKSDEDDDKL
Site 173S1371DEDDDKLSESKSDGR
Site 174S1373DDDKLSESKSDGRER
Site 175S1375DKLSESKSDGRERSK
Site 176S1381KSDGRERSKKSSVSD
Site 177S1384GRERSKKSSVSDAPV
Site 178S1385RERSKKSSVSDAPVH
Site 179S1387RSKKSSVSDAPVHIT
Site 180T1394SDAPVHITASGEPVP
Site 181S1396APVHITASGEPVPIS
Site 182S1403SGEPVPISEESEELD
Site 183S1406PVPISEESEELDQKT
Site 184T1413SEELDQKTFSICKER
Site 185S1415ELDQKTFSICKERMR
Site 186S1439DRPEKGLSEREQLEH
Site 187T1459IKIGDHITECLKEYT
Site 188Y1465ITECLKEYTNPEQIK
Site 189S1507AIKKRQESQQNSDQN
Site 190S1511RQESQQNSDQNSNLN
Site 191S1515QQNSDQNSNLNPHVI
Site 192T1534VERLKENTNHDDSSR
Site 193S1539ENTNHDDSSRDSYSS
Site 194S1540NTNHDDSSRDSYSSD
Site 195S1543HDDSSRDSYSSDRHL
Site 196Y1544DDSSRDSYSSDRHLT
Site 197S1545DSSRDSYSSDRHLTQ
Site 198S1546SSRDSYSSDRHLTQY
Site 199Y1553SDRHLTQYHDHHKDR
Site 200S1565KDRHQGDSYKKSDSR
Site 201Y1566DRHQGDSYKKSDSRK
Site 202S1569QGDSYKKSDSRKRPY
Site 203S1571DSYKKSDSRKRPYSS
Site 204Y1576SDSRKRPYSSFSNGK
Site 205S1577DSRKRPYSSFSNGKD
Site 206S1578SRKRPYSSFSNGKDH
Site 207S1580KRPYSSFSNGKDHRD
Site 208Y1591DHRDWDHYKQDSRYY
Site 209Y1597HYKQDSRYYSDREKH
Site 210Y1598YKQDSRYYSDREKHR
Site 211S1599KQDSRYYSDREKHRK
Site 212S1612RKLDDHRSRDHRSNL
Site 213S1617HRSRDHRSNLEGSLK
Site 214S1622HRSNLEGSLKDRSHS
Site 215S1627EGSLKDRSHSDHRSH
Site 216S1629SLKDRSHSDHRSHSD
Site 217S1633RSHSDHRSHSDHRLH
Site 218S1635HSDHRSHSDHRLHSD
Site 219S1641HSDHRLHSDHRSSSE
Site 220S1645RLHSDHRSSSEYTHH
Site 221S1646LHSDHRSSSEYTHHK
Site 222S1647HSDHRSSSEYTHHKS
Site 223Y1649DHRSSSEYTHHKSSR
Site 224T1650HRSSSEYTHHKSSRD
Site 225Y1658HHKSSRDYRYHSDWQ
Site 226Y1660KSSRDYRYHSDWQMD
Site 227S1662SRDYRYHSDWQMDHR
Site 228S1671WQMDHRASSSGPRSP
Site 229S1672QMDHRASSSGPRSPL
Site 230S1673MDHRASSSGPRSPLD
Site 231S1677ASSSGPRSPLDQRSY
Site 232S1683RSPLDQRSYGSRSPF
Site 233Y1684SPLDQRSYGSRSPFE
Site 234S1686LDQRSYGSRSPFEHS
Site 235S1688QRSYGSRSPFEHSVE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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