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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRDMT1
Full Name:
tRNA (cytosine-5-)-methyltransferase
Alias:
DNA (cytosine-5)-methyltransferase-like protein 2;DNA methyltransferase homolog HsaIIP;PuMet
Type:
Mass (Da):
44597
Number AA:
391
UniProt ID:
O14717
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y43
N
T
V
A
N
E
V
Y
K
Y
N
F
P
H
T
Site 2
Y45
V
A
N
E
V
Y
K
Y
N
F
P
H
T
Q
L
Site 3
T83
S
P
P
C
Q
P
F
T
R
I
G
R
Q
G
D
Site 4
T92
I
G
R
Q
G
D
M
T
D
S
R
T
N
S
F
Site 5
S94
R
Q
G
D
M
T
D
S
R
T
N
S
F
L
H
Site 6
T96
G
D
M
T
D
S
R
T
N
S
F
L
H
I
L
Site 7
S98
M
T
D
S
R
T
N
S
F
L
H
I
L
D
I
Site 8
Y115
R
L
Q
K
L
P
K
Y
I
L
L
E
N
V
K
Site 9
S127
N
V
K
G
F
E
V
S
S
T
R
D
L
L
I
Site 10
S128
V
K
G
F
E
V
S
S
T
R
D
L
L
I
Q
Site 11
T129
K
G
F
E
V
S
S
T
R
D
L
L
I
Q
T
Site 12
Y144
I
E
N
C
G
F
Q
Y
Q
E
F
L
L
S
P
Site 13
S150
Q
Y
Q
E
F
L
L
S
P
T
S
L
G
I
P
Site 14
S153
E
F
L
L
S
P
T
S
L
G
I
P
N
S
R
Site 15
S191
M
E
F
P
K
I
E
S
V
H
P
Q
K
Y
A
Site 16
Y197
E
S
V
H
P
Q
K
Y
A
M
D
V
E
N
K
Site 17
S215
K
N
V
E
P
N
I
S
F
D
G
S
I
Q
C
Site 18
S219
P
N
I
S
F
D
G
S
I
Q
C
S
G
K
D
Site 19
S246
H
R
K
N
Q
Q
D
S
D
L
S
V
K
M
L
Site 20
S249
N
Q
Q
D
S
D
L
S
V
K
M
L
K
D
F
Site 21
T261
K
D
F
L
E
D
D
T
D
V
N
Q
Y
L
L
Site 22
Y266
D
D
T
D
V
N
Q
Y
L
L
P
P
K
S
L
Site 23
Y297
S
V
C
F
T
K
G
Y
G
S
Y
I
E
G
T
Site 24
S299
C
F
T
K
G
Y
G
S
Y
I
E
G
T
G
S
Site 25
Y300
F
T
K
G
Y
G
S
Y
I
E
G
T
G
S
V
Site 26
S306
S
Y
I
E
G
T
G
S
V
L
Q
T
A
E
D
Site 27
T310
G
T
G
S
V
L
Q
T
A
E
D
V
Q
V
E
Site 28
S322
Q
V
E
N
I
Y
K
S
L
T
N
L
S
Q
E
Site 29
S327
Y
K
S
L
T
N
L
S
Q
E
E
Q
I
T
K
Site 30
T365
F
G
F
P
E
K
I
T
V
K
Q
R
Y
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation