PhosphoNET

           
Protein Info 
   
Short Name:  PHOX2A
Full Name:  Paired mesoderm homeobox protein 2A
Alias:  Aristaless homeobox protein homolog; ARIX; ARIX1 homeodomain protein; CFEOM2; FEOM2; NCAM2; Paired mesoderm homeobox protein 2A; Paired-like homeobox 2a; PHX2A; PMX2A
Type:  Transcription factor
Mass (Da):  29653
Number AA:  284
UniProt ID:  O14813
International Prot ID:  IPI00024171
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y9DYSYLNSYDSCVAAM
Site 2S11SYLNSYDSCVAAMEA
Site 3Y35SQPGGFQYSPLRPAF
Site 4S36QPGGFQYSPLRPAFP
Site 5Y75APYSAVPYKFFPEPS
Site 6T95RKQRRIRTTFTSAQL
Site 7T96KQRRIRTTFTSAQLK
Site 8S99RIRTTFTSAQLKELE
Site 9T112LERVFAETHYPDIYT
Site 10Y114RVFAETHYPDIYTRE
Site 11Y118ETHYPDIYTREELAL
Site 12S153RKQERAASAKGAAGA
Site 13S171KKGEARCSSEDDDSK
Site 14S172KGEARCSSEDDDSKE
Site 15S177CSSEDDDSKESTCSP
Site 16S180EDDDSKESTCSPTPD
Site 17T181DDDSKESTCSPTPDS
Site 18S183DSKESTCSPTPDSTA
Site 19T185KESTCSPTPDSTASL
Site 20S188TCSPTPDSTASLPPP
Site 21T189CSPTPDSTASLPPPP
Site 22S191PTPDSTASLPPPPAP
Site 23S202PPAPGLASPRLSPSP
Site 24S206GLASPRLSPSPLPVA
Site 25S208ASPRLSPSPLPVALG
Site 26S259KAWQPAESGPGPFSG
Site 27S265ESGPGPFSGVLSSFH
Site 28S269GPFSGVLSSFHRKPG
Site 29S270PFSGVLSSFHRKPGP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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