KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CAPN9
Full Name:
Calpain-9
Alias:
CAN9; CG36; Digestive tract-specific calpain; EC 3.4.22.-; GC36; NCL4; NCL-4
Type:
Protease
Mass (Da):
79097
Number AA:
690
UniProt ID:
O14815
International Prot ID:
IPI00009063
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0004198
PhosphoSite+
KinaseNET
Biological Process:
GO:0007586
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
V
P
K
D
A
R
I
T
H
S
S
G
Q
S
F
Site 2
S24
K
D
A
R
I
T
H
S
S
G
Q
S
F
E
Q
Site 3
S25
D
A
R
I
T
H
S
S
G
Q
S
F
E
Q
M
Site 4
S28
I
T
H
S
S
G
Q
S
F
E
Q
M
R
Q
E
Site 5
T41
Q
E
C
L
Q
R
G
T
L
F
E
D
A
D
F
Site 6
S51
E
D
A
D
F
P
A
S
N
S
S
L
F
Y
S
Site 7
S53
A
D
F
P
A
S
N
S
S
L
F
Y
S
E
R
Site 8
S54
D
F
P
A
S
N
S
S
L
F
Y
S
E
R
P
Site 9
S58
S
N
S
S
L
F
Y
S
E
R
P
Q
I
P
F
Site 10
S122
R
V
I
P
Q
D
Q
S
F
G
P
G
Y
A
G
Site 11
Y127
D
Q
S
F
G
P
G
Y
A
G
I
F
H
F
Q
Site 12
T152
V
I
D
D
R
L
P
T
F
R
D
R
L
V
F
Site 13
Y177
S
A
L
L
E
K
A
Y
A
K
L
N
G
S
Y
Site 14
S183
A
Y
A
K
L
N
G
S
Y
E
A
L
K
G
G
Site 15
T209
G
V
A
E
T
F
Q
T
K
E
A
P
E
N
F
Site 16
S228
E
K
A
L
K
R
G
S
L
L
G
C
F
I
D
Site 17
S238
G
C
F
I
D
T
R
S
A
A
E
S
E
A
R
Site 18
S242
D
T
R
S
A
A
E
S
E
A
R
T
P
F
G
Site 19
T246
A
A
E
S
E
A
R
T
P
F
G
L
I
K
G
Site 20
S265
V
T
G
I
D
Q
V
S
F
R
G
Q
R
I
E
Site 21
S288
G
Q
V
E
W
N
G
S
W
S
D
S
S
P
E
Site 22
S290
V
E
W
N
G
S
W
S
D
S
S
P
E
W
R
Site 23
S292
W
N
G
S
W
S
D
S
S
P
E
W
R
S
V
Site 24
S293
N
G
S
W
S
D
S
S
P
E
W
R
S
V
G
Site 25
S298
D
S
S
P
E
W
R
S
V
G
P
A
E
Q
K
Site 26
T337
K
V
E
I
C
N
L
T
P
D
A
L
E
E
D
Site 27
S357
E
V
T
V
H
Q
G
S
W
V
R
G
S
T
A
Site 28
S362
Q
G
S
W
V
R
G
S
T
A
G
G
C
R
N
Site 29
T363
G
S
W
V
R
G
S
T
A
G
G
C
R
N
F
Site 30
S383
T
N
P
Q
I
K
L
S
L
T
E
K
D
E
G
Site 31
T385
P
Q
I
K
L
S
L
T
E
K
D
E
G
Q
E
Site 32
S395
D
E
G
Q
E
E
C
S
F
L
V
A
L
M
Q
Site 33
Y423
L
T
I
G
Y
A
I
Y
E
C
P
D
K
D
E
Site 34
S442
D
F
F
R
Y
H
A
S
R
A
R
S
K
T
F
Site 35
S446
Y
H
A
S
R
A
R
S
K
T
F
I
N
L
R
Site 36
T448
A
S
R
A
R
S
K
T
F
I
N
L
R
E
V
Site 37
S456
F
I
N
L
R
E
V
S
D
R
F
K
L
P
P
Site 38
T472
E
Y
I
L
I
P
S
T
F
E
P
H
Q
E
A
Site 39
S487
D
F
C
L
R
I
F
S
E
K
K
A
I
T
R
Site 40
T511
L
P
E
P
P
K
P
T
P
P
D
Q
E
T
E
Site 41
T517
P
T
P
P
D
Q
E
T
E
E
E
Q
R
F
R
Site 42
S562
D
I
K
F
K
K
L
S
L
I
S
C
K
N
I
Site 43
T575
N
I
I
S
L
M
D
T
S
G
N
G
K
L
E
Site 44
S608
L
R
F
D
A
D
K
S
G
T
M
S
T
Y
E
Site 45
S612
A
D
K
S
G
T
M
S
T
Y
E
L
R
T
A
Site 46
Y614
K
S
G
T
M
S
T
Y
E
L
R
T
A
L
K
Site 47
S669
S
R
V
F
Q
A
L
S
T
K
N
K
E
F
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation