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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FSCN2
Full Name:
Fascin-2
Alias:
Fascin 2, actin-bundling protein, retinal; Retinal fascin; RFSN; RP30
Type:
Cytoskeletal protein
Mass (Da):
55057
Number AA:
492
UniProt ID:
O14926
International Prot ID:
IPI00018293
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
Uniprot
OncoNet
Molecular Function:
GO:0051015
GO:0030674
PhosphoSite+
KinaseNET
Biological Process:
GO:0051017
GO:0009653
GO:0050896
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
Q
F
G
L
V
N
D
T
D
R
Y
L
T
A
E
Site 2
Y23
L
V
N
D
T
D
R
Y
L
T
A
E
S
F
G
Site 3
T25
N
D
T
D
R
Y
L
T
A
E
S
F
G
F
K
Site 4
S28
D
R
Y
L
T
A
E
S
F
G
F
K
V
N
A
Site 5
S39
K
V
N
A
S
A
P
S
L
K
R
K
Q
T
W
Site 6
T45
P
S
L
K
R
K
Q
T
W
V
L
E
P
D
P
Site 7
Y68
R
S
S
H
L
G
R
Y
L
S
A
E
E
D
G
Site 8
S70
S
H
L
G
R
Y
L
S
A
E
E
D
G
R
V
Site 9
S104
D
G
R
W
V
L
R
S
E
P
H
G
R
F
F
Site 10
T114
H
G
R
F
F
G
G
T
E
D
Q
L
S
C
F
Site 11
S145
H
P
Q
A
H
L
L
S
V
S
R
R
R
Y
V
Site 12
S147
Q
A
H
L
L
S
V
S
R
R
R
Y
V
H
L
Site 13
Y151
L
S
V
S
R
R
R
Y
V
H
L
C
P
R
E
Site 14
Y184
L
I
F
R
S
R
R
Y
C
L
K
S
C
D
S
Site 15
S188
S
R
R
Y
C
L
K
S
C
D
S
R
Y
L
R
Site 16
S191
Y
C
L
K
S
C
D
S
R
Y
L
R
S
D
G
Site 17
Y193
L
K
S
C
D
S
R
Y
L
R
S
D
G
R
L
Site 18
S196
C
D
S
R
Y
L
R
S
D
G
R
L
V
W
E
Site 19
Y210
E
P
E
P
R
A
C
Y
T
L
E
F
K
A
G
Site 20
Y228
F
K
D
C
D
G
H
Y
L
A
P
V
G
P
A
Site 21
T244
T
L
K
A
G
R
N
T
R
P
G
K
D
E
L
Site 22
S272
A
A
N
H
R
Y
V
S
V
R
Q
G
V
N
V
Site 23
T304
D
Q
E
T
K
K
C
T
F
Y
S
S
T
G
G
Site 24
Y306
E
T
K
K
C
T
F
Y
S
S
T
G
G
Y
W
Site 25
Y312
F
Y
S
S
T
G
G
Y
W
T
L
V
T
H
G
Site 26
T314
S
S
T
G
G
Y
W
T
L
V
T
H
G
G
I
Site 27
S348
R
R
V
A
L
K
A
S
N
G
R
Y
V
C
M
Site 28
Y352
L
K
A
S
N
G
R
Y
V
C
M
K
K
N
G
Site 29
S365
N
G
Q
L
A
A
I
S
D
F
V
G
K
D
E
Site 30
T404
R
G
S
N
Q
L
D
T
N
R
S
V
Y
D
V
Site 31
S407
N
Q
L
D
T
N
R
S
V
Y
D
V
F
H
L
Site 32
Y409
L
D
T
N
R
S
V
Y
D
V
F
H
L
S
F
Site 33
S415
V
Y
D
V
F
H
L
S
F
S
D
G
A
Y
R
Site 34
Y421
L
S
F
S
D
G
A
Y
R
I
R
G
R
D
G
Site 35
Y432
G
R
D
G
G
F
W
Y
T
G
S
H
G
S
V
Site 36
T433
R
D
G
G
F
W
Y
T
G
S
H
G
S
V
C
Site 37
S438
W
Y
T
G
S
H
G
S
V
C
S
D
G
E
R
Site 38
S465
R
L
A
I
R
A
R
S
G
K
Y
L
R
G
G
Site 39
Y468
I
R
A
R
S
G
K
Y
L
R
G
G
A
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation