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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HAT1
Full Name:
Histone acetyltransferase type B catalytic subunit
Alias:
histone acetyltransferase 1; histone acetyltransferase type B catalytic; KAT1
Type:
Acetyltransferase; EC 2.3.1.48
Mass (Da):
49513
Number AA:
419
UniProt ID:
O14929
International Prot ID:
IPI00024719
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0004402
GO:0005515
GO:0004468
PhosphoSite+
KinaseNET
Biological Process:
GO:0006323
GO:0006348
GO:0016573
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
M
E
K
F
L
V
E
Y
K
S
A
V
E
K
K
Site 2
S16
K
F
L
V
E
Y
K
S
A
V
E
K
K
L
A
Site 3
T50
D
L
E
N
D
I
R
T
F
F
P
E
Y
T
H
Site 4
Y55
I
R
T
F
F
P
E
Y
T
H
Q
L
F
G
D
Site 5
T65
Q
L
F
G
D
D
E
T
A
F
G
Y
K
G
L
Site 6
Y69
D
D
E
T
A
F
G
Y
K
G
L
K
I
L
L
Site 7
Y78
G
L
K
I
L
L
Y
Y
I
A
G
S
L
S
T
Site 8
Y91
S
T
M
F
R
V
E
Y
A
S
K
V
D
E
N
Site 9
S93
M
F
R
V
E
Y
A
S
K
V
D
E
N
F
D
Site 10
S128
T
N
T
N
D
F
L
S
L
L
E
K
E
V
D
Site 11
S150
L
H
T
Y
S
V
L
S
P
T
G
G
E
N
F
Site 12
T158
P
T
G
G
E
N
F
T
F
Q
I
Y
K
A
D
Site 13
Y162
E
N
F
T
F
Q
I
Y
K
A
D
M
T
C
R
Site 14
Y174
T
C
R
G
F
R
E
Y
H
E
R
L
Q
T
F
Site 15
Y201
V
D
D
E
R
W
H
Y
F
L
V
F
E
K
Y
Site 16
Y208
Y
F
L
V
F
E
K
Y
N
K
D
G
A
T
L
Site 17
T214
K
Y
N
K
D
G
A
T
L
F
A
T
V
G
Y
Site 18
Y225
T
V
G
Y
M
T
V
Y
N
Y
Y
V
Y
P
D
Site 19
Y227
G
Y
M
T
V
Y
N
Y
Y
V
Y
P
D
K
T
Site 20
Y228
Y
M
T
V
Y
N
Y
Y
V
Y
P
D
K
T
R
Site 21
Y230
T
V
Y
N
Y
Y
V
Y
P
D
K
T
R
P
R
Site 22
T234
Y
Y
V
Y
P
D
K
T
R
P
R
V
S
Q
M
Site 23
S239
D
K
T
R
P
R
V
S
Q
M
L
I
L
T
P
Site 24
T259
H
G
A
Q
L
L
E
T
V
H
R
Y
Y
T
E
Site 25
Y263
L
L
E
T
V
H
R
Y
Y
T
E
F
P
T
V
Site 26
Y264
L
E
T
V
H
R
Y
Y
T
E
F
P
T
V
L
Site 27
T265
E
T
V
H
R
Y
Y
T
E
F
P
T
V
L
D
Site 28
T269
R
Y
Y
T
E
F
P
T
V
L
D
I
T
A
E
Site 29
T274
F
P
T
V
L
D
I
T
A
E
D
P
S
K
S
Site 30
S279
D
I
T
A
E
D
P
S
K
S
Y
V
K
L
R
Site 31
S281
T
A
E
D
P
S
K
S
Y
V
K
L
R
D
F
Site 32
Y282
A
E
D
P
S
K
S
Y
V
K
L
R
D
F
V
Site 33
Y332
K
Q
H
A
R
R
V
Y
E
I
L
R
L
L
V
Site 34
S343
R
L
L
V
T
D
M
S
D
A
E
Q
Y
R
S
Site 35
S350
S
D
A
E
Q
Y
R
S
Y
R
L
D
I
K
R
Site 36
Y351
D
A
E
Q
Y
R
S
Y
R
L
D
I
K
R
R
Site 37
S361
D
I
K
R
R
L
I
S
P
Y
K
K
K
Q
R
Site 38
Y363
K
R
R
L
I
S
P
Y
K
K
K
Q
R
D
L
Site 39
T383
C
L
R
P
E
E
L
T
N
Q
M
N
Q
I
E
Site 40
S401
Q
H
E
Q
L
E
E
S
F
Q
E
L
V
E
D
Site 41
Y409
F
Q
E
L
V
E
D
Y
R
R
V
I
E
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation