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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TFEC
Full Name:
Transcription factor EC
Alias:
Class E basic helix-loop-helix protein 34;Transcription factor EC-like
Type:
Mass (Da):
38788
Number AA:
347
UniProt ID:
O14948
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
L
D
H
Q
I
I
N
Site 2
T11
D
H
Q
I
I
N
P
T
L
K
W
S
Q
P
A
Site 3
S15
I
N
P
T
L
K
W
S
Q
P
A
V
P
S
G
Site 4
S21
W
S
Q
P
A
V
P
S
G
G
P
L
V
Q
H
Site 5
S35
H
A
H
T
T
L
D
S
D
A
G
L
T
E
N
Site 6
T40
L
D
S
D
A
G
L
T
E
N
P
L
T
K
L
Site 7
S74
D
I
I
G
M
E
S
S
F
K
E
E
G
A
D
Site 8
S82
F
K
E
E
G
A
D
S
P
L
L
M
Q
R
T
Site 9
S93
M
Q
R
T
L
S
G
S
I
L
D
V
Y
S
G
Site 10
Y98
S
G
S
I
L
D
V
Y
S
G
E
Q
G
I
S
Site 11
S99
G
S
I
L
D
V
Y
S
G
E
Q
G
I
S
P
Site 12
S105
Y
S
G
E
Q
G
I
S
P
I
N
M
G
L
T
Site 13
T112
S
P
I
N
M
G
L
T
S
A
S
C
P
S
S
Site 14
S119
T
S
A
S
C
P
S
S
L
P
M
K
R
E
I
Site 15
T127
L
P
M
K
R
E
I
T
E
T
D
T
R
A
L
Site 16
T129
M
K
R
E
I
T
E
T
D
T
R
A
L
A
K
Site 17
Y153
L
I
E
R
R
R
R
Y
N
I
N
Y
R
I
K
Site 18
Y157
R
R
R
Y
N
I
N
Y
R
I
K
E
L
G
T
Site 19
T164
Y
R
I
K
E
L
G
T
L
I
P
K
S
N
D
Site 20
S169
L
G
T
L
I
P
K
S
N
D
P
D
M
R
W
Site 21
T180
D
M
R
W
N
K
G
T
I
L
K
A
S
V
E
Site 22
T248
V
D
L
G
A
H
V
T
K
Q
Q
S
H
P
E
Site 23
Y261
P
E
Q
N
S
V
D
Y
C
Q
Q
L
T
V
S
Site 24
T266
V
D
Y
C
Q
Q
L
T
V
S
Q
G
P
S
P
Site 25
S268
Y
C
Q
Q
L
T
V
S
Q
G
P
S
P
E
L
Site 26
S272
L
T
V
S
Q
G
P
S
P
E
L
C
D
Q
A
Site 27
T290
S
D
P
L
S
Y
F
T
D
L
S
F
S
A
A
Site 28
T312
D
G
M
L
L
D
D
T
I
S
P
F
G
T
D
Site 29
S326
D
P
L
L
S
A
T
S
P
A
V
S
K
E
S
Site 30
S330
S
A
T
S
P
A
V
S
K
E
S
S
R
R
S
Site 31
S333
S
P
A
V
S
K
E
S
S
R
R
S
S
F
S
Site 32
S334
P
A
V
S
K
E
S
S
R
R
S
S
F
S
S
Site 33
S337
S
K
E
S
S
R
R
S
S
F
S
S
D
D
G
Site 34
S338
K
E
S
S
R
R
S
S
F
S
S
D
D
G
D
Site 35
S340
S
S
R
R
S
S
F
S
S
D
D
G
D
E
L
Site 36
S341
S
R
R
S
S
F
S
S
D
D
G
D
E
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation