PhosphoNET

           
Protein Info 
   
Short Name:  DSCR3
Full Name:  Down syndrome critical region protein 3
Alias:  Down syndrome critical region protein A
Type: 
Mass (Da):  33010
Number AA:  297
UniProt ID:  O14972
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y16IKRANKVYHAGEVLS
Site 2S30SGVVVISSKDSVQHQ
Site 3S33VVISSKDSVQHQGVS
Site 4S86VKPGKFPSGKTEIPF
Site 5T89GKFPSGKTEIPFEFP
Site 6Y106LKGNKVLYETYHGVF
Site 7T151APQKGKFTPSPVDFT
Site 8S153QKGKFTPSPVDFTIT
Site 9T158TPSPVDFTITPETLQ
Site 10T160SPVDFTITPETLQNV
Site 11T185LRGHLNSTNCVITQP
Site 12S208SSEAAIRSVELQLVR
Site 13Y225TCGCAEGYARDATEI
Site 14T230EGYARDATEIQNIQI
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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