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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC27A2
Full Name:
Very long-chain acyl-CoA synthetase
Alias:
ACSVL1; FACVL1; FACVL1, FATP2, VLACS; FATP2; HsT17226; S27A2; Solute carrier family 27 (fatty acid transporter) member 2; Very long-chain-fatty-acid-CoA ligase; Very-long-chain acyl-CoA synthetase; VLACS; VLCS
Type:
EC 6.2.1.3; EC 6.2.1.-; Ligase
Mass (Da):
70312
Number AA:
620
UniProt ID:
O14975
International Prot ID:
IPI00024787
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
GO:0005782
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004467
GO:0050197
PhosphoSite+
KinaseNET
Biological Process:
GO:0000038
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S45
A
V
G
R
R
V
R
S
Y
G
Q
R
R
P
A
Site 2
Y46
V
G
R
R
V
R
S
Y
G
Q
R
R
P
A
R
Site 3
T54
G
Q
R
R
P
A
R
T
I
L
R
A
F
L
E
Site 4
T66
F
L
E
K
A
R
Q
T
P
H
K
P
F
L
L
Site 5
T80
L
F
R
D
E
T
L
T
Y
A
Q
V
D
R
R
Site 6
Y81
F
R
D
E
T
L
T
Y
A
Q
V
D
R
R
S
Site 7
S88
Y
A
Q
V
D
R
R
S
N
Q
V
A
R
A
L
Site 8
S158
G
A
K
V
L
L
V
S
P
E
L
Q
A
A
V
Site 9
S171
A
V
E
E
I
L
P
S
L
K
K
D
D
V
S
Site 10
S178
S
L
K
K
D
D
V
S
I
Y
Y
V
S
R
T
Site 11
Y180
K
K
D
D
V
S
I
Y
Y
V
S
R
T
S
N
Site 12
Y181
K
D
D
V
S
I
Y
Y
V
S
R
T
S
N
T
Site 13
S186
I
Y
Y
V
S
R
T
S
N
T
D
G
I
D
S
Site 14
S193
S
N
T
D
G
I
D
S
F
L
D
K
V
D
E
Site 15
S202
L
D
K
V
D
E
V
S
T
E
P
I
P
E
S
Site 16
S209
S
T
E
P
I
P
E
S
W
R
S
E
V
T
F
Site 17
S212
P
I
P
E
S
W
R
S
E
V
T
F
S
T
P
Site 18
T215
E
S
W
R
S
E
V
T
F
S
T
P
A
L
Y
Site 19
S217
W
R
S
E
V
T
F
S
T
P
A
L
Y
I
Y
Site 20
T218
R
S
E
V
T
F
S
T
P
A
L
Y
I
Y
T
Site 21
S226
P
A
L
Y
I
Y
T
S
G
T
T
G
L
P
K
Site 22
T238
L
P
K
A
A
M
I
T
H
Q
R
I
W
Y
G
Site 23
T246
H
Q
R
I
W
Y
G
T
G
L
T
F
V
S
G
Site 24
T249
I
W
Y
G
T
G
L
T
F
V
S
G
L
K
A
Site 25
S252
G
T
G
L
T
F
V
S
G
L
K
A
D
D
V
Site 26
S293
L
A
L
R
T
K
F
S
A
S
Q
F
W
D
D
Site 27
S295
L
R
T
K
F
S
A
S
Q
F
W
D
D
C
R
Site 28
Y304
F
W
D
D
C
R
K
Y
N
V
T
V
I
Q
Y
Site 29
Y311
Y
N
V
T
V
I
Q
Y
I
G
E
L
L
R
Y
Site 30
Y318
Y
I
G
E
L
L
R
Y
L
C
N
S
P
Q
K
Site 31
S322
L
L
R
Y
L
C
N
S
P
Q
K
P
N
D
R
Site 32
T393
Y
L
Q
K
K
I
I
T
Y
D
L
I
K
Y
D
Site 33
Y399
I
T
Y
D
L
I
K
Y
D
V
E
K
D
E
P
Site 34
Y413
P
V
R
D
E
N
G
Y
C
V
R
V
P
K
G
Site 35
Y460
V
F
K
K
G
D
L
Y
F
N
S
G
D
L
L
Site 36
S463
K
G
D
L
Y
F
N
S
G
D
L
L
M
V
D
Site 37
Y476
V
D
H
E
N
F
I
Y
F
H
D
R
V
G
D
Site 38
T494
W
K
G
E
N
V
A
T
T
E
V
A
D
T
V
Site 39
Y513
F
V
Q
E
V
N
V
Y
G
V
H
V
P
D
H
Site 40
S528
E
G
R
I
G
M
A
S
I
K
M
K
E
N
H
Site 41
Y549
L
F
Q
H
I
A
D
Y
L
P
S
Y
A
R
P
Site 42
Y553
I
A
D
Y
L
P
S
Y
A
R
P
R
F
L
R
Site 43
T570
D
T
I
E
I
T
G
T
F
K
H
R
K
M
T
Site 44
T577
T
F
K
H
R
K
M
T
L
V
E
E
G
F
N
Site 45
Y602
L
D
D
T
A
K
M
Y
V
P
M
T
E
D
I
Site 46
Y610
V
P
M
T
E
D
I
Y
N
A
I
S
A
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation