KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF263
Full Name:
Zinc finger protein 263
Alias:
Zinc finger protein FPM315;Zinc finger protein with KRAB and SCAN domains 12
Type:
Mass (Da):
77299
Number AA:
683
UniProt ID:
O14978
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
S
G
P
G
S
Q
E
R
E
G
L
L
Site 2
S25
L
E
E
D
C
A
W
S
Q
E
L
P
P
P
D
Site 3
S36
P
P
P
D
P
G
P
S
P
E
A
S
H
L
R
Site 4
S40
P
G
P
S
P
E
A
S
H
L
R
F
R
R
F
Site 5
S60
A
G
P
R
E
A
L
S
R
L
Q
E
L
C
H
Site 6
T76
W
L
R
P
E
M
R
T
K
E
Q
I
L
E
L
Site 7
T114
E
S
G
E
E
A
V
T
L
V
E
D
M
Q
R
Site 8
T131
G
R
L
R
Q
Q
V
T
N
H
G
R
G
T
E
Site 9
T137
V
T
N
H
G
R
G
T
E
V
L
L
E
E
P
Site 10
T149
E
E
P
L
P
L
E
T
A
R
E
S
P
S
F
Site 11
S153
P
L
E
T
A
R
E
S
P
S
F
K
L
E
P
Site 12
S155
E
T
A
R
E
S
P
S
F
K
L
E
P
M
E
Site 13
T163
F
K
L
E
P
M
E
T
E
R
S
P
G
P
R
Site 14
S166
E
P
M
E
T
E
R
S
P
G
P
R
L
Q
E
Site 15
S178
L
Q
E
L
L
G
P
S
P
Q
R
D
P
Q
A
Site 16
S218
T
G
P
Q
L
P
E
S
L
E
D
V
A
M
Y
Site 17
Y225
S
L
E
D
V
A
M
Y
I
S
Q
E
E
W
G
Site 18
S237
E
W
G
H
Q
D
P
S
K
R
A
L
S
R
D
Site 19
S242
D
P
S
K
R
A
L
S
R
D
T
V
Q
E
S
Site 20
T245
K
R
A
L
S
R
D
T
V
Q
E
S
Y
E
N
Site 21
S249
S
R
D
T
V
Q
E
S
Y
E
N
V
D
S
L
Site 22
Y250
R
D
T
V
Q
E
S
Y
E
N
V
D
S
L
E
Site 23
S255
E
S
Y
E
N
V
D
S
L
E
S
H
I
P
S
Site 24
S258
E
N
V
D
S
L
E
S
H
I
P
S
Q
E
V
Site 25
S262
S
L
E
S
H
I
P
S
Q
E
V
P
G
T
Q
Site 26
T268
P
S
Q
E
V
P
G
T
Q
V
G
Q
G
G
K
Site 27
S280
G
G
K
L
W
D
P
S
V
Q
S
C
K
E
G
Site 28
S283
L
W
D
P
S
V
Q
S
C
K
E
G
L
S
P
Site 29
S289
Q
S
C
K
E
G
L
S
P
R
G
P
A
P
G
Site 30
S308
E
N
L
E
G
V
P
S
V
C
S
E
N
I
H
Site 31
S331
A
R
G
E
V
P
W
S
P
E
L
G
R
P
H
Site 32
S341
L
G
R
P
H
D
R
S
Q
G
D
W
A
P
P
Site 33
S362
Q
A
L
A
G
A
S
S
G
R
E
L
G
R
P
Site 34
S388
P
L
C
G
K
N
F
S
N
N
S
N
L
I
R
Site 35
S391
G
K
N
F
S
N
N
S
N
L
I
R
H
Q
R
Site 36
S423
G
G
N
P
R
F
L
S
L
H
R
A
H
L
G
Site 37
T455
H
L
T
R
H
Q
R
T
H
T
G
E
K
P
Y
Site 38
T457
T
R
H
Q
R
T
H
T
G
E
K
P
Y
Q
C
Site 39
Y462
T
H
T
G
E
K
P
Y
Q
C
N
I
C
G
K
Site 40
T483
N
L
H
R
H
Q
R
T
H
T
G
E
K
P
Y
Site 41
T485
H
R
H
Q
R
T
H
T
G
E
K
P
Y
K
C
Site 42
Y490
T
H
T
G
E
K
P
Y
K
C
P
E
C
G
E
Site 43
S503
G
E
I
F
A
H
S
S
N
L
L
R
H
Q
R
Site 44
T513
L
R
H
Q
R
I
H
T
G
E
R
P
Y
K
C
Site 45
Y518
I
H
T
G
E
R
P
Y
K
C
P
E
C
G
K
Site 46
S526
K
C
P
E
C
G
K
S
F
S
R
S
S
H
L
Site 47
S528
P
E
C
G
K
S
F
S
R
S
S
H
L
V
I
Site 48
S530
C
G
K
S
F
S
R
S
S
H
L
V
I
H
E
Site 49
S531
G
K
S
F
S
R
S
S
H
L
V
I
H
E
R
Site 50
Y546
T
H
E
R
E
R
L
Y
P
F
S
E
C
G
E
Site 51
S549
R
E
R
L
Y
P
F
S
E
C
G
E
A
V
S
Site 52
S556
S
E
C
G
E
A
V
S
D
S
T
P
F
L
T
Site 53
S558
C
G
E
A
V
S
D
S
T
P
F
L
T
N
H
Site 54
T559
G
E
A
V
S
D
S
T
P
F
L
T
N
H
G
Site 55
T579
K
K
L
F
E
C
L
T
C
G
K
S
F
R
Q
Site 56
T598
T
R
H
Q
R
T
H
T
G
E
K
P
Y
K
C
Site 57
T606
G
E
K
P
Y
K
C
T
L
C
G
E
N
F
S
Site 58
S613
T
L
C
G
E
N
F
S
H
R
S
N
L
I
R
Site 59
T626
I
R
H
Q
R
I
H
T
G
E
K
P
Y
T
C
Site 60
Y631
I
H
T
G
E
K
P
Y
T
C
H
E
C
G
D
Site 61
S639
T
C
H
E
C
G
D
S
F
S
H
S
S
N
R
Site 62
S641
H
E
C
G
D
S
F
S
H
S
S
N
R
I
R
Site 63
S643
C
G
D
S
F
S
H
S
S
N
R
I
R
H
L
Site 64
S644
G
D
S
F
S
H
S
S
N
R
I
R
H
L
R
Site 65
T654
I
R
H
L
R
T
H
T
G
E
R
P
Y
K
C
Site 66
Y659
T
H
T
G
E
R
P
Y
K
C
S
E
C
G
E
Site 67
S662
G
E
R
P
Y
K
C
S
E
C
G
E
S
F
S
Site 68
S667
K
C
S
E
C
G
E
S
F
S
R
S
S
R
L
Site 69
S669
S
E
C
G
E
S
F
S
R
S
S
R
L
M
S
Site 70
S671
C
G
E
S
F
S
R
S
S
R
L
M
S
H
Q
Site 71
S672
G
E
S
F
S
R
S
S
R
L
M
S
H
Q
R
Site 72
S676
S
R
S
S
R
L
M
S
H
Q
R
T
H
T
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation