KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ATP2A1
Full Name:
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Alias:
AT2A1; ATP2A; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; Calcium pump 1; EC 3.6.3.8
Type:
Sarcoplasmic reticulum membrane, Membrane, Integral membrane protein
Mass (Da):
110252
Number AA:
1001
UniProt ID:
O14983
International Prot ID:
IPI00396118
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005793
GO:0031673
GO:0031674
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005509
GO:0005388
PhosphoSite+
KinaseNET
Biological Process:
GO:0006754
GO:0006200
GO:0070059
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
T
T
E
E
C
L
A
Y
F
G
V
S
E
T
T
Site 2
T25
V
S
E
T
T
G
L
T
P
D
Q
V
K
R
N
Site 3
Y36
V
K
R
N
L
E
K
Y
G
L
N
E
L
P
A
Site 4
T48
L
P
A
E
E
G
K
T
L
W
E
L
V
I
E
Site 5
T84
W
F
E
E
G
E
E
T
I
T
A
F
V
E
P
Site 6
T86
E
E
G
E
E
T
I
T
A
F
V
E
P
F
V
Site 7
Y122
A
I
E
A
L
K
E
Y
E
P
E
M
G
K
V
Site 8
S136
V
Y
R
A
D
R
K
S
V
Q
R
I
K
A
R
Site 9
T171
R
I
L
A
I
K
S
T
T
L
R
V
D
Q
S
Site 10
S178
T
T
L
R
V
D
Q
S
I
L
T
G
E
S
V
Site 11
S184
Q
S
I
L
T
G
E
S
V
S
V
I
K
H
T
Site 12
S186
I
L
T
G
E
S
V
S
V
I
K
H
T
E
P
Site 13
S210
D
K
K
N
M
L
F
S
G
T
N
I
A
A
G
Site 14
T247
A
A
T
E
Q
D
K
T
P
L
Q
Q
K
L
D
Site 15
S261
D
E
F
G
E
Q
L
S
K
V
I
S
L
I
C
Site 16
S335
K
K
N
A
I
V
R
S
L
P
S
V
E
T
L
Site 17
T353
S
V
I
C
S
D
K
T
G
T
L
T
T
N
Q
Site 18
T357
S
D
K
T
G
T
L
T
T
N
Q
M
S
V
C
Site 19
T385
L
L
N
E
F
S
I
T
G
S
T
Y
A
P
E
Site 20
S387
N
E
F
S
I
T
G
S
T
Y
A
P
E
G
E
Site 21
T388
E
F
S
I
T
G
S
T
Y
A
P
E
G
E
V
Site 22
S424
C
A
L
C
N
D
S
S
L
D
F
N
E
A
K
Site 23
Y434
F
N
E
A
K
G
V
Y
E
K
V
G
E
A
T
Site 24
T441
Y
E
K
V
G
E
A
T
E
T
A
L
T
T
L
Site 25
T446
E
A
T
E
T
A
L
T
T
L
V
E
K
M
N
Site 26
T457
E
K
M
N
V
F
N
T
D
V
R
S
L
S
K
Site 27
S461
V
F
N
T
D
V
R
S
L
S
K
V
E
R
A
Site 28
S463
N
T
D
V
R
S
L
S
K
V
E
R
A
N
A
Site 29
S473
E
R
A
N
A
C
N
S
V
I
R
Q
L
M
K
Site 30
T484
Q
L
M
K
K
E
F
T
L
E
F
S
R
D
R
Site 31
S488
K
E
F
T
L
E
F
S
R
D
R
K
S
M
S
Site 32
S493
E
F
S
R
D
R
K
S
M
S
V
Y
C
S
P
Site 33
S495
S
R
D
R
K
S
M
S
V
Y
C
S
P
A
K
Site 34
Y497
D
R
K
S
M
S
V
Y
C
S
P
A
K
S
S
Site 35
S499
K
S
M
S
V
Y
C
S
P
A
K
S
S
R
A
Site 36
S503
V
Y
C
S
P
A
K
S
S
R
A
A
V
G
N
Site 37
Y527
G
V
I
D
R
C
N
Y
V
R
V
G
T
T
R
Site 38
T538
G
T
T
R
V
P
L
T
G
P
V
K
E
K
I
Site 39
T554
A
V
I
K
E
W
G
T
G
R
D
T
L
R
C
Site 40
T558
E
W
G
T
G
R
D
T
L
R
C
L
A
L
A
Site 41
T569
L
A
L
A
T
R
D
T
P
P
K
R
E
E
M
Site 42
S581
E
E
M
V
L
D
D
S
A
R
F
L
E
Y
E
Site 43
S610
P
R
K
E
V
T
G
S
I
Q
L
C
R
D
A
Site 44
T625
G
I
R
V
I
M
I
T
G
D
N
K
G
T
A
Site 45
Y653
E
E
V
A
D
R
A
Y
T
G
R
E
F
D
D
Site 46
T654
E
V
A
D
R
A
Y
T
G
R
E
F
D
D
L
Site 47
S685
R
V
E
P
S
H
K
S
K
I
V
E
Y
L
Q
Site 48
S693
K
I
V
E
Y
L
Q
S
Y
D
E
I
T
A
M
Site 49
T698
L
Q
S
Y
D
E
I
T
A
M
T
G
D
G
V
Site 50
S722
E
I
G
I
A
M
G
S
G
T
A
V
A
K
T
Site 51
T724
G
I
A
M
G
S
G
T
A
V
A
K
T
A
S
Site 52
S731
T
A
V
A
K
T
A
S
E
M
V
L
A
D
D
Site 53
Y754
V
E
E
G
R
A
I
Y
N
N
M
K
Q
F
I
Site 54
Y763
N
M
K
Q
F
I
R
Y
L
I
S
S
N
V
G
Site 55
S823
I
M
D
R
P
P
R
S
P
K
E
P
L
I
S
Site 56
S830
S
P
K
E
P
L
I
S
G
W
L
F
F
R
Y
Site 57
S915
E
M
C
N
A
L
N
S
L
S
E
N
Q
S
L
Site 58
S917
C
N
A
L
N
S
L
S
E
N
Q
S
L
L
R
Site 59
S921
N
S
L
S
E
N
Q
S
L
L
R
M
P
P
W
Site 60
Y991
L
K
F
V
A
R
N
Y
L
E
D
P
E
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation