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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYN3
Full Name:
Synapsin-3
Alias:
SYN3, Synapsin IIIa; Synapsin III
Type:
Vesicle protein
Mass (Da):
63303
Number AA:
580
UniProt ID:
O14994
International Prot ID:
IPI00298984
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005509
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0007269
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
N
F
L
R
R
R
L
S
D
S
S
F
M
A
N
Site 2
S11
L
R
R
R
L
S
D
S
S
F
M
A
N
L
P
Site 3
S12
R
R
R
L
S
D
S
S
F
M
A
N
L
P
N
Site 4
Y21
M
A
N
L
P
N
G
Y
M
T
D
L
Q
R
P
Site 5
S30
T
D
L
Q
R
P
D
S
S
T
S
S
P
A
S
Site 6
S31
D
L
Q
R
P
D
S
S
T
S
S
P
A
S
P
Site 7
T32
L
Q
R
P
D
S
S
T
S
S
P
A
S
P
A
Site 8
S33
Q
R
P
D
S
S
T
S
S
P
A
S
P
A
M
Site 9
S34
R
P
D
S
S
T
S
S
P
A
S
P
A
M
E
Site 10
S37
S
S
T
S
S
P
A
S
P
A
M
E
R
R
H
Site 11
S51
H
P
Q
P
L
A
A
S
F
S
S
P
G
S
S
Site 12
S53
Q
P
L
A
A
S
F
S
S
P
G
S
S
L
F
Site 13
S54
P
L
A
A
S
F
S
S
P
G
S
S
L
F
S
Site 14
S57
A
S
F
S
S
P
G
S
S
L
F
S
S
L
S
Site 15
S58
S
F
S
S
P
G
S
S
L
F
S
S
L
S
S
Site 16
S61
S
P
G
S
S
L
F
S
S
L
S
S
A
M
K
Site 17
S62
P
G
S
S
L
F
S
S
L
S
S
A
M
K
Q
Site 18
S64
S
S
L
F
S
S
L
S
S
A
M
K
Q
A
P
Site 19
S65
S
L
F
S
S
L
S
S
A
M
K
Q
A
P
Q
Site 20
T85
M
E
P
P
G
P
S
T
P
I
V
Q
R
P
R
Site 21
Y107
A
H
T
D
W
S
K
Y
F
H
G
K
K
V
N
Site 22
T150
M
Q
V
V
R
N
G
T
K
V
V
S
R
S
F
Site 23
S170
L
V
R
Q
H
A
Y
S
M
A
L
G
E
D
Y
Site 24
S197
P
A
V
N
S
L
Y
S
V
Y
N
F
C
S
K
Site 25
Y199
V
N
S
L
Y
S
V
Y
N
F
C
S
K
P
W
Site 26
T229
K
F
P
L
V
E
Q
T
F
F
P
N
H
K
P
Site 27
T239
P
N
H
K
P
M
V
T
A
P
H
F
P
V
V
Site 28
Y280
V
V
A
M
A
K
T
Y
A
T
T
E
A
F
I
Site 29
Y291
E
A
F
I
D
S
K
Y
D
I
R
I
Q
K
I
Site 30
Y305
I
G
S
N
Y
K
A
Y
M
R
T
S
I
S
G
Site 31
T318
S
G
N
W
K
A
N
T
G
S
A
M
L
E
Q
Site 32
S340
R
L
W
V
D
S
C
S
E
M
F
G
G
L
D
Site 33
Y362
H
S
K
D
G
R
D
Y
I
I
E
V
M
D
S
Site 34
S405
M
P
G
G
T
A
P
S
P
L
R
P
W
A
P
Site 35
S416
P
W
A
P
Q
I
K
S
A
K
S
P
G
Q
A
Site 36
S419
P
Q
I
K
S
A
K
S
P
G
Q
A
Q
L
G
Site 37
S447
G
G
P
R
Q
A
Q
S
P
Q
P
Q
R
S
G
Site 38
S453
Q
S
P
Q
P
Q
R
S
G
S
P
S
Q
Q
R
Site 39
S455
P
Q
P
Q
R
S
G
S
P
S
Q
Q
R
L
S
Site 40
S457
P
Q
R
S
G
S
P
S
Q
Q
R
L
S
P
Q
Site 41
S462
S
P
S
Q
Q
R
L
S
P
Q
G
Q
Q
P
L
Site 42
S470
P
Q
G
Q
Q
P
L
S
P
Q
S
G
S
P
Q
Site 43
S473
Q
Q
P
L
S
P
Q
S
G
S
P
Q
Q
Q
R
Site 44
S475
P
L
S
P
Q
S
G
S
P
Q
Q
Q
R
S
P
Site 45
S481
G
S
P
Q
Q
Q
R
S
P
G
S
P
Q
L
S
Site 46
S484
Q
Q
Q
R
S
P
G
S
P
Q
L
S
R
A
S
Site 47
S488
S
P
G
S
P
Q
L
S
R
A
S
S
G
S
S
Site 48
S491
S
P
Q
L
S
R
A
S
S
G
S
S
P
N
Q
Site 49
S492
P
Q
L
S
R
A
S
S
G
S
S
P
N
Q
A
Site 50
S494
L
S
R
A
S
S
G
S
S
P
N
Q
A
S
K
Site 51
S495
S
R
A
S
S
G
S
S
P
N
Q
A
S
K
P
Site 52
S500
G
S
S
P
N
Q
A
S
K
P
G
A
T
L
A
Site 53
S508
K
P
G
A
T
L
A
S
Q
P
R
P
P
V
Q
Site 54
T519
P
P
V
Q
G
R
S
T
S
Q
Q
G
E
E
S
Site 55
S520
P
V
Q
G
R
S
T
S
Q
Q
G
E
E
S
K
Site 56
S526
T
S
Q
Q
G
E
E
S
K
K
P
A
P
P
H
Site 57
S539
P
H
P
H
L
N
K
S
Q
S
L
T
N
S
L
Site 58
S541
P
H
L
N
K
S
Q
S
L
T
N
S
L
S
T
Site 59
T543
L
N
K
S
Q
S
L
T
N
S
L
S
T
S
D
Site 60
S545
K
S
Q
S
L
T
N
S
L
S
T
S
D
T
S
Site 61
S547
Q
S
L
T
N
S
L
S
T
S
D
T
S
Q
R
Site 62
S549
L
T
N
S
L
S
T
S
D
T
S
Q
R
G
T
Site 63
T551
N
S
L
S
T
S
D
T
S
Q
R
G
T
P
S
Site 64
S552
S
L
S
T
S
D
T
S
Q
R
G
T
P
S
E
Site 65
T556
S
D
T
S
Q
R
G
T
P
S
E
D
E
A
K
Site 66
S558
T
S
Q
R
G
T
P
S
E
D
E
A
K
A
E
Site 67
S573
T
I
R
N
L
R
K
S
F
A
S
L
F
S
D
Site 68
S576
N
L
R
K
S
F
A
S
L
F
S
D
_
_
_
Site 69
S579
K
S
F
A
S
L
F
S
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation