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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLXNB2
Full Name:
Plexin-B2
Alias:
MM1; PLEXB2; PLXB2
Type:
Intracellular, Membrane, Integral membrane protein
Mass (Da):
205127
Number AA:
1838
UniProt ID:
O15031
International Prot ID:
IPI00853369
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0016020
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0004872
GO:0060089
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0007165
GO:0007275
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
G
L
L
G
A
G
A
S
L
R
P
R
K
L
D
Site 2
Y419
D
G
R
I
L
K
V
Y
L
T
P
D
G
T
S
Site 3
S452
V
L
S
G
D
L
G
S
L
Y
A
M
T
Q
D
Site 4
T1124
T
N
L
N
K
A
M
T
L
Q
E
A
E
A
F
Site 5
Y1220
I
A
V
S
V
Y
C
Y
W
R
K
S
Q
Q
A
Site 6
S1224
V
Y
C
Y
W
R
K
S
Q
Q
A
E
R
E
Y
Site 7
Y1231
S
Q
Q
A
E
R
E
Y
E
K
I
K
S
Q
L
Site 8
S1236
R
E
Y
E
K
I
K
S
Q
L
E
G
L
E
E
Site 9
S1244
Q
L
E
G
L
E
E
S
V
R
D
R
C
K
K
Site 10
Y1277
A
G
I
P
V
L
D
Y
K
T
Y
T
D
R
V
Site 11
S1320
E
Q
A
L
Y
Q
F
S
N
L
L
N
S
K
S
Site 12
S1325
Q
F
S
N
L
L
N
S
K
S
F
L
I
N
F
Site 13
S1327
S
N
L
L
N
S
K
S
F
L
I
N
F
I
H
Site 14
S1343
L
E
N
Q
R
E
F
S
A
R
A
K
V
Y
F
Site 15
Y1349
F
S
A
R
A
K
V
Y
F
A
S
L
L
T
V
Site 16
Y1364
A
L
H
G
K
L
E
Y
Y
T
D
I
M
H
T
Site 17
Y1365
L
H
G
K
L
E
Y
Y
T
D
I
M
H
T
L
Site 18
Y1380
F
L
E
L
L
E
Q
Y
V
V
A
K
N
P
K
Site 19
S1393
P
K
L
M
L
R
R
S
E
T
V
V
E
R
M
Site 20
T1395
L
M
L
R
R
S
E
T
V
V
E
R
M
L
S
Site 21
Y1410
N
W
M
S
I
C
L
Y
Q
Y
L
K
D
S
A
Site 22
Y1412
M
S
I
C
L
Y
Q
Y
L
K
D
S
A
G
E
Site 23
S1416
L
Y
Q
Y
L
K
D
S
A
G
E
P
L
Y
K
Site 24
Y1422
D
S
A
G
E
P
L
Y
K
L
F
K
A
I
K
Site 25
Y1446
A
V
Q
K
K
A
K
Y
T
L
N
D
T
G
L
Site 26
T1486
V
K
V
L
N
C
D
T
I
S
Q
V
K
E
K
Site 27
Y1499
E
K
I
I
D
Q
V
Y
R
G
Q
P
C
S
C
Site 28
S1512
S
C
W
P
R
P
D
S
V
V
L
E
W
R
P
Site 29
S1521
V
L
E
W
R
P
G
S
T
A
Q
I
L
S
D
Site 30
S1527
G
S
T
A
Q
I
L
S
D
L
D
L
T
S
Q
Site 31
T1532
I
L
S
D
L
D
L
T
S
Q
R
E
G
R
W
Site 32
S1533
L
S
D
L
D
L
T
S
Q
R
E
G
R
W
K
Site 33
Y1548
R
V
N
T
L
M
H
Y
N
V
R
D
G
A
T
Site 34
S1564
I
L
S
K
V
G
V
S
Q
Q
P
E
D
S
Q
Site 35
S1570
V
S
Q
Q
P
E
D
S
Q
Q
D
L
P
G
E
Site 36
T1595
V
W
H
L
V
R
P
T
D
E
V
D
E
G
K
Site 37
S1603
D
E
V
D
E
G
K
S
K
R
G
S
V
K
E
Site 38
S1607
E
G
K
S
K
R
G
S
V
K
E
K
E
R
T
Site 39
T1614
S
V
K
E
K
E
R
T
K
A
I
T
E
I
Y
Site 40
T1618
K
E
R
T
K
A
I
T
E
I
Y
L
T
R
L
Site 41
T1623
A
I
T
E
I
Y
L
T
R
L
L
S
V
K
G
Site 42
S1627
I
Y
L
T
R
L
L
S
V
K
G
T
L
Q
Q
Site 43
T1631
R
L
L
S
V
K
G
T
L
Q
Q
F
V
D
N
Site 44
T1681
D
T
I
H
I
W
K
T
N
S
L
P
L
R
F
Site 45
S1731
T
R
T
E
H
K
L
S
R
D
S
P
S
N
K
Site 46
S1734
E
H
K
L
S
R
D
S
P
S
N
K
L
L
Y
Site 47
S1736
K
L
S
R
D
S
P
S
N
K
L
L
Y
A
K
Site 48
Y1741
S
P
S
N
K
L
L
Y
A
K
E
I
S
T
Y
Site 49
Y1748
Y
A
K
E
I
S
T
Y
K
K
M
V
E
D
Y
Site 50
Y1755
Y
K
K
M
V
E
D
Y
Y
K
G
I
R
Q
M
Site 51
Y1756
K
K
M
V
E
D
Y
Y
K
G
I
R
Q
M
V
Site 52
T1772
V
S
D
Q
D
M
N
T
H
L
A
E
I
S
R
Site 53
T1782
A
E
I
S
R
A
H
T
D
S
L
N
T
L
V
Site 54
Y1795
L
V
A
L
H
Q
L
Y
Q
Y
T
Q
K
Y
Y
Site 55
Y1801
L
Y
Q
Y
T
Q
K
Y
Y
D
E
I
I
N
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation