KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
Syntaphilin
Full Name:
Syntaphilin
Alias:
bA314N13.5; KIAA0374; SNPH
Type:
Vesicle protein
Mass (Da):
53537
Number AA:
494
UniProt ID:
O15079
International Prot ID:
IPI00006054
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0016021
GO:0045202
Uniprot
OncoNet
Molecular Function:
GO:0017075
PhosphoSite+
KinaseNET
Biological Process:
GO:0016081
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
M
S
L
P
G
S
R
R
T
S
A
G
S
Site 2
T11
S
L
P
G
S
R
R
T
S
A
G
S
R
R
R
Site 3
S12
L
P
G
S
R
R
T
S
A
G
S
R
R
R
T
Site 4
S15
S
R
R
T
S
A
G
S
R
R
R
T
S
P
P
Site 5
T19
S
A
G
S
R
R
R
T
S
P
P
V
S
V
R
Site 6
S20
A
G
S
R
R
R
T
S
P
P
V
S
V
R
D
Site 7
S24
R
R
T
S
P
P
V
S
V
R
D
A
Y
G
T
Site 8
Y29
P
V
S
V
R
D
A
Y
G
T
S
S
L
S
S
Site 9
T31
S
V
R
D
A
Y
G
T
S
S
L
S
S
S
S
Site 10
S32
V
R
D
A
Y
G
T
S
S
L
S
S
S
S
N
Site 11
S33
R
D
A
Y
G
T
S
S
L
S
S
S
S
N
S
Site 12
S35
A
Y
G
T
S
S
L
S
S
S
S
N
S
G
S
Site 13
S36
Y
G
T
S
S
L
S
S
S
S
N
S
G
S
Y
Site 14
S37
G
T
S
S
L
S
S
S
S
N
S
G
S
Y
K
Site 15
S38
T
S
S
L
S
S
S
S
N
S
G
S
Y
K
G
Site 16
S40
S
L
S
S
S
S
N
S
G
S
Y
K
G
S
D
Site 17
S42
S
S
S
S
N
S
G
S
Y
K
G
S
D
S
S
Site 18
Y43
S
S
S
N
S
G
S
Y
K
G
S
D
S
S
P
Site 19
S46
N
S
G
S
Y
K
G
S
D
S
S
P
T
P
R
Site 20
S48
G
S
Y
K
G
S
D
S
S
P
T
P
R
R
S
Site 21
S49
S
Y
K
G
S
D
S
S
P
T
P
R
R
S
M
Site 22
T51
K
G
S
D
S
S
P
T
P
R
R
S
M
K
Y
Site 23
S55
S
S
P
T
P
R
R
S
M
K
Y
T
L
C
S
Site 24
Y58
T
P
R
R
S
M
K
Y
T
L
C
S
D
N
H
Site 25
T59
P
R
R
S
M
K
Y
T
L
C
S
D
N
H
G
Site 26
T71
N
H
G
I
K
P
P
T
P
E
Q
Y
L
T
P
Site 27
Y75
K
P
P
T
P
E
Q
Y
L
T
P
L
Q
Q
K
Site 28
T77
P
T
P
E
Q
Y
L
T
P
L
Q
Q
K
E
V
Site 29
T96
L
K
A
R
L
K
D
T
Q
D
R
L
Q
D
R
Site 30
T105
D
R
L
Q
D
R
D
T
E
I
D
D
L
K
T
Site 31
T112
T
E
I
D
D
L
K
T
Q
L
S
R
M
Q
E
Site 32
T151
Q
L
K
Q
V
I
D
T
V
K
N
N
L
I
D
Site 33
Y166
K
D
K
G
L
Q
K
Y
F
V
D
I
N
I
Q
Site 34
T179
I
Q
N
K
K
L
E
T
L
L
H
S
M
E
V
Site 35
T197
G
M
A
K
E
D
G
T
G
E
S
A
G
G
S
Site 36
S200
K
E
D
G
T
G
E
S
A
G
G
S
P
A
R
Site 37
S204
T
G
E
S
A
G
G
S
P
A
R
S
L
T
R
Site 38
S208
A
G
G
S
P
A
R
S
L
T
R
S
S
T
Y
Site 39
T210
G
S
P
A
R
S
L
T
R
S
S
T
Y
T
K
Site 40
S212
P
A
R
S
L
T
R
S
S
T
Y
T
K
L
S
Site 41
S213
A
R
S
L
T
R
S
S
T
Y
T
K
L
S
D
Site 42
T214
R
S
L
T
R
S
S
T
Y
T
K
L
S
D
P
Site 43
T216
L
T
R
S
S
T
Y
T
K
L
S
D
P
A
V
Site 44
S219
S
S
T
Y
T
K
L
S
D
P
A
V
C
G
D
Site 45
S234
R
Q
P
G
D
P
S
S
G
S
A
E
D
G
A
Site 46
S236
P
G
D
P
S
S
G
S
A
E
D
G
A
D
S
Site 47
S243
S
A
E
D
G
A
D
S
G
F
A
A
A
D
D
Site 48
T251
G
F
A
A
A
D
D
T
L
S
R
T
D
A
L
Site 49
S253
A
A
A
D
D
T
L
S
R
T
D
A
L
E
A
Site 50
S261
R
T
D
A
L
E
A
S
S
L
L
S
S
G
V
Site 51
S266
E
A
S
S
L
L
S
S
G
V
D
C
G
T
E
Site 52
T272
S
S
G
V
D
C
G
T
E
E
T
S
L
H
S
Site 53
S276
D
C
G
T
E
E
T
S
L
H
S
S
F
G
L
Site 54
S280
E
E
T
S
L
H
S
S
F
G
L
G
P
R
F
Site 55
S290
L
G
P
R
F
P
A
S
N
T
Y
E
K
L
L
Site 56
Y293
R
F
P
A
S
N
T
Y
E
K
L
L
C
G
M
Site 57
T327
Q
Y
Q
P
D
L
D
T
I
L
E
K
V
T
Q
Site 58
S344
V
C
G
T
D
P
E
S
G
D
R
C
P
E
L
Site 59
S356
P
E
L
D
A
H
P
S
G
P
R
D
P
N
S
Site 60
S363
S
G
P
R
D
P
N
S
A
V
V
V
T
V
G
Site 61
T380
L
E
A
P
E
P
I
T
R
G
P
T
P
Q
R
Site 62
T384
E
P
I
T
R
G
P
T
P
Q
R
P
G
A
N
Site 63
S397
A
N
P
N
P
G
Q
S
V
S
V
V
C
P
M
Site 64
S399
P
N
P
G
Q
S
V
S
V
V
C
P
M
E
E
Site 65
Y420
A
E
K
E
P
K
S
Y
W
S
R
H
Y
I
V
Site 66
Y425
K
S
Y
W
S
R
H
Y
I
V
D
L
L
A
V
Site 67
S446
T
V
A
W
L
C
R
S
Q
R
R
Q
G
Q
P
Site 68
Y455
R
R
Q
G
Q
P
I
Y
N
I
S
S
L
L
R
Site 69
S476
L
H
S
I
R
R
I
S
C
R
S
L
S
Q
P
Site 70
S479
I
R
R
I
S
C
R
S
L
S
Q
P
S
P
S
Site 71
S481
R
I
S
C
R
S
L
S
Q
P
S
P
S
P
A
Site 72
S484
C
R
S
L
S
Q
P
S
P
S
P
A
G
G
G
Site 73
S486
S
L
S
Q
P
S
P
S
P
A
G
G
G
S
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation