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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KPNA5
Full Name:
Importin subunit alpha-6
Alias:
Importin alpha 6; IPOA6; Karyopherin alpha 5; Karyopherin subunit alpha-5; SRP6
Type:
Import protein
Mass (Da):
60349
Number AA:
536
UniProt ID:
O15131
International Prot ID:
IPI00413214
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006607
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
P
G
K
D
N
Y
R
Site 2
Y9
A
S
P
G
K
D
N
Y
R
M
K
S
Y
K
N
Site 3
S13
K
D
N
Y
R
M
K
S
Y
K
N
K
A
L
N
Site 4
Y14
D
N
Y
R
M
K
S
Y
K
N
K
A
L
N
P
Site 5
Y51
L
F
K
R
R
N
V
Y
L
P
R
N
D
E
S
Site 6
S58
Y
L
P
R
N
D
E
S
M
L
E
S
P
I
Q
Site 7
S62
N
D
E
S
M
L
E
S
P
I
Q
D
P
D
I
Site 8
S71
I
Q
D
P
D
I
S
S
T
V
P
I
P
E
E
Site 9
T72
Q
D
P
D
I
S
S
T
V
P
I
P
E
E
E
Site 10
S154
W
A
L
T
N
I
A
S
G
T
F
L
H
T
K
Site 11
T219
P
P
L
L
E
L
L
T
N
S
N
R
L
T
T
Site 12
S221
L
L
E
L
L
T
N
S
N
R
L
T
T
T
R
Site 13
T225
L
T
N
S
N
R
L
T
T
T
R
N
A
V
W
Site 14
T226
T
N
S
N
R
L
T
T
T
R
N
A
V
W
A
Site 15
S248
K
N
P
P
P
N
F
S
K
V
S
P
C
L
N
Site 16
S277
A
D
V
C
W
A
L
S
Y
L
S
D
G
P
N
Site 17
Y278
D
V
C
W
A
L
S
Y
L
S
D
G
P
N
D
Site 18
Y308
E
L
L
M
H
N
D
Y
K
V
V
S
P
A
L
Site 19
S312
H
N
D
Y
K
V
V
S
P
A
L
R
A
V
G
Site 20
S346
P
C
L
L
H
L
L
S
S
P
K
E
S
I
R
Site 21
S347
C
L
L
H
L
L
S
S
P
K
E
S
I
R
K
Site 22
S351
L
L
S
S
P
K
E
S
I
R
K
E
A
C
W
Site 23
T359
I
R
K
E
A
C
W
T
V
S
N
I
T
A
G
Site 24
T410
T
N
A
T
S
G
G
T
P
E
Q
I
R
Y
L
Site 25
Y416
G
T
P
E
Q
I
R
Y
L
V
A
L
G
C
I
Site 26
S456
L
R
L
G
E
Q
E
S
K
Q
N
G
I
G
I
Site 27
Y474
C
A
L
I
E
E
A
Y
G
L
D
K
I
E
F
Site 28
Y491
S
H
E
N
Q
E
I
Y
Q
K
A
F
D
L
I
Site 29
Y501
A
F
D
L
I
E
H
Y
F
G
V
E
E
D
D
Site 30
S510
G
V
E
E
D
D
P
S
I
V
P
Q
V
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation