KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ARPC2
Full Name:
Actin-related protein 2/3 complex subunit 2
Alias:
Arp2/3 complex 34 kDa subunit
Type:
Mass (Da):
34315
Number AA:
300
UniProt ID:
O15144
International Prot ID:
IPI00005161
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005885
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005198
GO:0005200
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
GO:0008064
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
N
N
R
I
I
E
E
T
L
A
L
K
F
E
N
Site 2
Y43
A
D
F
D
G
V
L
Y
H
I
S
N
P
N
G
Site 3
S46
D
G
V
L
Y
H
I
S
N
P
N
G
D
K
T
Site 4
T53
S
N
P
N
G
D
K
T
K
V
M
V
S
I
S
Site 5
S58
D
K
T
K
V
M
V
S
I
S
L
K
F
Y
K
Site 6
Y64
V
S
I
S
L
K
F
Y
K
E
L
Q
A
H
G
Site 7
Y80
D
E
L
L
K
R
V
Y
G
S
F
L
V
N
P
Site 8
Y91
L
V
N
P
E
S
G
Y
N
V
S
L
L
Y
D
Site 9
S94
P
E
S
G
Y
N
V
S
L
L
Y
D
L
E
N
Site 10
S108
N
L
P
A
S
K
D
S
I
V
H
Q
A
G
M
Site 11
Y128
F
A
S
V
F
E
K
Y
F
Q
F
Q
E
E
G
Site 12
Y146
E
N
R
A
V
I
H
Y
R
D
D
E
T
M
Y
Site 13
T151
I
H
Y
R
D
D
E
T
M
Y
V
E
S
K
K
Site 14
Y153
Y
R
D
D
E
T
M
Y
V
E
S
K
K
D
R
Site 15
S156
D
E
T
M
Y
V
E
S
K
K
D
R
V
T
V
Site 16
T162
E
S
K
K
D
R
V
T
V
V
F
S
T
V
F
Site 17
S192
F
K
E
G
R
R
A
S
H
T
A
P
Q
V
L
Site 18
T194
E
G
R
R
A
S
H
T
A
P
Q
V
L
F
S
Site 19
S201
T
A
P
Q
V
L
F
S
H
R
E
P
P
L
E
Site 20
T212
P
P
L
E
L
K
D
T
D
A
A
V
G
D
N
Site 21
T232
F
V
L
F
P
R
H
T
N
A
S
A
R
D
N
Site 22
S235
F
P
R
H
T
N
A
S
A
R
D
N
T
I
N
Site 23
T240
N
A
S
A
R
D
N
T
I
N
L
I
H
T
F
Site 24
T246
N
T
I
N
L
I
H
T
F
R
D
Y
L
H
Y
Site 25
Y250
L
I
H
T
F
R
D
Y
L
H
Y
H
I
K
C
Site 26
Y253
T
F
R
D
Y
L
H
Y
H
I
K
C
S
K
A
Site 27
Y261
H
I
K
C
S
K
A
Y
I
H
T
R
M
R
A
Site 28
T270
H
T
R
M
R
A
K
T
S
D
F
L
K
V
L
Site 29
T291
A
E
K
K
E
M
K
T
I
T
G
K
T
F
S
Site 30
T293
K
K
E
M
K
T
I
T
G
K
T
F
S
S
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation