PhosphoNET

           
Protein Info 
   
Short Name:  PGRMC2
Full Name:  Membrane-associated progesterone receptor component 2
Alias:  DG6; PGRC2; PMBP; Progesterone membrane-binding protein; Steroid receptor protein DG6
Type:  Receptor, Progesterone
Mass (Da):  23818
Number AA:  223
UniProt ID:  O15173
International Prot ID:  IPI00005202
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0020037  GO:0005496  GO:0003707 PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T12DGDVKLGTLGSGSES
Site 2S15VKLGTLGSGSESSND
Site 3S17LGTLGSGSESSNDGG
Site 4S19TLGSGSESSNDGGSE
Site 5S20LGSGSESSNDGGSES
Site 6S25ESSNDGGSESPGDAG
Site 7S27SNDGGSESPGDAGAA
Site 8S90GAGAGEESPATSLPR
Site 9T93AGEESPATSLPRMKK
Site 10S94GEESPATSLPRMKKR
Site 11Y111SLEQLRQYDGSRNPR
Site 12S114QLRQYDGSRNPRILL
Site 13T131NGKVFDVTKGSKFYG
Site 14S134VFDVTKGSKFYGPAG
Site 15Y137VTKGSKFYGPAGPYG
Site 16Y143FYGPAGPYGIFAGRD
Site 17T157DASRGLATFCLDKDA
Site 18Y169KDALRDEYDDLSDLN
Site 19S173RDEYDDLSDLNAVQM
Site 20Y194EMQFKEKYDYVGRLL
Site 21Y196QFKEKYDYVGRLLKP
Site 22S208LKPGEEPSEYTDEED
Site 23Y210PGEEPSEYTDEEDTK
Site 24T211GEEPSEYTDEEDTKD
Site 25T216EYTDEEDTKDHNKQD
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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