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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB22
Full Name:
Zinc finger and BTB domain-containing protein 22
Alias:
Protein BING1;Zinc finger and BTB domain-containing protein 22A;Zinc finger protein 297
Type:
Mass (Da):
65602
Number AA:
634
UniProt ID:
O15209
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
E
P
S
P
L
S
P
S
G
A
Site 2
S7
_
M
E
P
S
P
L
S
P
S
G
A
A
L
P
Site 3
S9
E
P
S
P
L
S
P
S
G
A
A
L
P
L
P
Site 4
S60
Q
G
Q
L
C
D
V
S
I
R
V
Q
G
R
E
Site 5
S79
R
A
V
L
A
A
S
S
P
Y
F
H
D
Q
V
Site 6
S153
L
L
R
E
G
R
A
S
A
T
T
T
I
T
T
Site 7
T156
E
G
R
A
S
A
T
T
T
I
T
T
A
A
A
Site 8
T157
G
R
A
S
A
T
T
T
I
T
T
A
A
A
T
Site 9
S165
I
T
T
A
A
A
T
S
V
T
V
P
G
A
G
Site 10
S175
V
P
G
A
G
V
P
S
G
S
G
G
T
V
A
Site 11
T185
G
G
T
V
A
P
A
T
M
G
S
A
R
S
H
Site 12
S188
V
A
P
A
T
M
G
S
A
R
S
H
A
S
S
Site 13
S191
A
T
M
G
S
A
R
S
H
A
S
S
R
A
S
Site 14
S194
G
S
A
R
S
H
A
S
S
R
A
S
E
N
Q
Site 15
S195
S
A
R
S
H
A
S
S
R
A
S
E
N
Q
S
Site 16
S198
S
H
A
S
S
R
A
S
E
N
Q
S
P
S
S
Site 17
S202
S
R
A
S
E
N
Q
S
P
S
S
S
N
Y
F
Site 18
S204
A
S
E
N
Q
S
P
S
S
S
N
Y
F
S
P
Site 19
S205
S
E
N
Q
S
P
S
S
S
N
Y
F
S
P
R
Site 20
S206
E
N
Q
S
P
S
S
S
N
Y
F
S
P
R
E
Site 21
Y208
Q
S
P
S
S
S
N
Y
F
S
P
R
E
S
T
Site 22
S210
P
S
S
S
N
Y
F
S
P
R
E
S
T
D
F
Site 23
S214
N
Y
F
S
P
R
E
S
T
D
F
S
S
S
S
Site 24
T215
Y
F
S
P
R
E
S
T
D
F
S
S
S
S
Q
Site 25
S218
P
R
E
S
T
D
F
S
S
S
S
Q
E
A
F
Site 26
S221
S
T
D
F
S
S
S
S
Q
E
A
F
A
A
S
Site 27
S228
S
Q
E
A
F
A
A
S
A
V
G
S
G
E
R
Site 28
S232
F
A
A
S
A
V
G
S
G
E
R
R
G
G
G
Site 29
T285
G
A
G
L
R
R
P
T
Y
T
P
P
S
I
M
Site 30
Y286
A
G
L
R
R
P
T
Y
T
P
P
S
I
M
P
Site 31
T287
G
L
R
R
P
T
Y
T
P
P
S
I
M
P
Q
Site 32
T310
G
G
N
C
P
A
P
T
P
L
V
P
Q
D
P
Site 33
S343
E
D
E
E
L
G
G
S
S
R
V
P
V
G
G
Site 34
S344
D
E
E
L
G
G
S
S
R
V
P
V
G
G
G
Site 35
T355
V
G
G
G
P
E
A
T
L
S
I
S
D
V
R
Site 36
S357
G
G
P
E
A
T
L
S
I
S
D
V
R
T
L
Site 37
S359
P
E
A
T
L
S
I
S
D
V
R
T
L
S
E
Site 38
T363
L
S
I
S
D
V
R
T
L
S
E
P
P
D
K
Site 39
S365
I
S
D
V
R
T
L
S
E
P
P
D
K
G
E
Site 40
Y387
S
S
N
D
F
G
P
Y
E
G
G
G
P
V
A
Site 41
S399
P
V
A
G
L
D
D
S
G
G
P
T
P
S
S
Site 42
T403
L
D
D
S
G
G
P
T
P
S
S
Y
A
P
S
Site 43
S405
D
S
G
G
P
T
P
S
S
Y
A
P
S
H
P
Site 44
S406
S
G
G
P
T
P
S
S
Y
A
P
S
H
P
P
Site 45
Y407
G
G
P
T
P
S
S
Y
A
P
S
H
P
P
R
Site 46
S410
T
P
S
S
Y
A
P
S
H
P
P
R
P
L
L
Site 47
S431
N
Q
I
L
V
F
P
S
S
S
S
S
S
S
S
Site 48
S432
Q
I
L
V
F
P
S
S
S
S
S
S
S
S
Q
Site 49
S433
I
L
V
F
P
S
S
S
S
S
S
S
S
Q
A
Site 50
S434
L
V
F
P
S
S
S
S
S
S
S
S
Q
A
P
Site 51
S435
V
F
P
S
S
S
S
S
S
S
S
Q
A
P
G
Site 52
S436
F
P
S
S
S
S
S
S
S
S
Q
A
P
G
Q
Site 53
S437
P
S
S
S
S
S
S
S
S
Q
A
P
G
Q
P
Site 54
S438
S
S
S
S
S
S
S
S
Q
A
P
G
Q
P
P
Site 55
T477
V
G
G
V
P
G
G
T
G
S
G
D
G
N
K
Site 56
S479
G
V
P
G
G
T
G
S
G
D
G
N
K
I
F
Site 57
S498
G
K
A
F
S
H
K
S
M
R
D
R
H
V
N
Site 58
T534
H
L
T
E
H
M
K
T
H
T
G
L
K
P
Y
Site 59
Y541
T
H
T
G
L
K
P
Y
E
C
G
V
C
A
K
Site 60
T580
G
A
V
P
G
P
G
T
P
T
G
P
S
L
P
Site 61
T582
V
P
G
P
G
T
P
T
G
P
S
L
P
S
K
Site 62
S585
P
G
T
P
T
G
P
S
L
P
S
K
R
E
S
Site 63
S588
P
T
G
P
S
L
P
S
K
R
E
S
P
G
V
Site 64
S592
S
L
P
S
K
R
E
S
P
G
V
G
G
G
S
Site 65
S599
S
P
G
V
G
G
G
S
G
D
E
A
S
A
A
Site 66
S604
G
G
S
G
D
E
A
S
A
A
T
P
P
S
S
Site 67
T607
G
D
E
A
S
A
A
T
P
P
S
S
R
R
V
Site 68
S610
A
S
A
A
T
P
P
S
S
R
R
V
W
S
P
Site 69
S611
S
A
A
T
P
P
S
S
R
R
V
W
S
P
P
Site 70
S616
P
S
S
R
R
V
W
S
P
P
R
V
H
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation