KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WDR46
Full Name:
WD repeat-containing protein 46
Alias:
WD repeat-containing protein BING4
Type:
Mass (Da):
68041
Number AA:
610
UniProt ID:
O15213
International Prot ID:
IPI00023126
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
P
K
K
D
K
L
Q
T
K
R
K
K
P
R
R
Site 2
Y28
K
R
K
K
P
R
R
Y
W
E
E
E
T
V
P
Site 3
T33
R
R
Y
W
E
E
E
T
V
P
T
T
A
G
A
Site 4
T36
W
E
E
E
T
V
P
T
T
A
G
A
S
P
G
Site 5
T37
E
E
E
T
V
P
T
T
A
G
A
S
P
G
P
Site 6
S41
V
P
T
T
A
G
A
S
P
G
P
P
R
N
K
Site 7
Y62
P
Q
R
P
K
N
A
Y
I
L
K
K
S
R
I
Site 8
S67
N
A
Y
I
L
K
K
S
R
I
S
K
K
P
Q
Site 9
S70
I
L
K
K
S
R
I
S
K
K
P
Q
V
P
K
Site 10
S87
R
E
W
K
N
P
E
S
Q
R
G
L
S
G
A
Site 11
S92
P
E
S
Q
R
G
L
S
G
A
Q
D
P
F
P
Site 12
S124
K
S
R
K
L
P
H
S
K
A
K
T
R
S
R
Site 13
T128
L
P
H
S
K
A
K
T
R
S
R
L
E
V
A
Site 14
S143
E
A
E
E
E
E
T
S
I
K
A
A
R
S
E
Site 15
T168
E
G
E
D
G
E
D
T
A
K
I
C
Q
A
D
Site 16
Y199
N
L
R
Q
F
G
P
Y
R
L
N
Y
S
R
T
Site 17
Y203
F
G
P
Y
R
L
N
Y
S
R
T
G
R
H
L
Site 18
T206
Y
R
L
N
Y
S
R
T
G
R
H
L
A
F
G
Site 19
Y262
Q
N
R
W
L
H
I
Y
D
N
Q
G
I
E
L
Site 20
T279
I
R
R
C
D
R
V
T
R
L
E
F
L
P
F
Site 21
S324
A
G
R
L
D
V
M
S
Q
N
P
Y
N
A
V
Site 22
Y328
D
V
M
S
Q
N
P
Y
N
A
V
I
H
L
G
Site 23
T340
H
L
G
H
S
N
G
T
V
S
L
W
S
P
A
Site 24
S342
G
H
S
N
G
T
V
S
L
W
S
P
A
M
K
Site 25
S345
N
G
T
V
S
L
W
S
P
A
M
K
E
P
L
Site 26
Y373
A
V
D
S
T
G
T
Y
M
A
T
S
G
L
D
Site 27
T391
K
I
F
D
L
R
G
T
Y
Q
P
L
S
T
R
Site 28
Y392
I
F
D
L
R
G
T
Y
Q
P
L
S
T
R
T
Site 29
S396
R
G
T
Y
Q
P
L
S
T
R
T
L
P
H
G
Site 30
S433
W
A
G
Q
G
K
A
S
P
P
S
L
E
Q
P
Site 31
S436
Q
G
K
A
S
P
P
S
L
E
Q
P
Y
L
T
Site 32
Y441
P
P
S
L
E
Q
P
Y
L
T
H
R
L
S
G
Site 33
T443
S
L
E
Q
P
Y
L
T
H
R
L
S
G
P
V
Site 34
S447
P
Y
L
T
H
R
L
S
G
P
V
H
G
L
Q
Site 35
T467
D
V
L
G
V
G
H
T
G
G
I
T
S
M
L
Site 36
Y491
D
G
L
E
S
N
P
Y
R
S
R
K
Q
R
Q
Site 37
S528
L
A
E
V
D
V
I
S
L
E
Q
G
K
K
E
Site 38
Y542
E
Q
I
E
R
L
G
Y
D
P
Q
A
K
A
P
Site 39
S560
K
P
K
Q
K
G
R
S
S
T
A
S
L
V
K
Site 40
S561
P
K
Q
K
G
R
S
S
T
A
S
L
V
K
R
Site 41
T562
K
Q
K
G
R
S
S
T
A
S
L
V
K
R
K
Site 42
S564
K
G
R
S
S
T
A
S
L
V
K
R
K
R
K
Site 43
S584
H
R
D
K
V
R
Q
S
L
Q
Q
Q
H
H
K
Site 44
S603
K
P
T
G
A
R
P
S
A
L
D
R
F
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation