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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GNPAT
Full Name:
Dihydroxyacetone phosphate acyltransferase
Alias:
Acyl-CoA:dihydroxyacetonephosphateacyltransferase; DAPAT; DAP-AT; DHAPAT; DHAP-AT; Glyceronephosphate O-acyltransferase; Glycerone-phosphate O-acyltransferase
Type:
Lipid Metabolism - glycerophospholipid; Transferase; EC 2.3.1.42
Mass (Da):
77188
Number AA:
680
UniProt ID:
O15228
International Prot ID:
IPI00005677
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0005777
Uniprot
OncoNet
Molecular Function:
GO:0016287
PhosphoSite+
KinaseNET
Biological Process:
GO:0006631
GO:0009887
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
E
S
S
S
S
S
N
S
Y
F
S
Site 2
S6
_
_
M
E
S
S
S
S
S
N
S
Y
F
S
V
Site 3
S7
_
M
E
S
S
S
S
S
N
S
Y
F
S
V
G
Site 4
S9
E
S
S
S
S
S
N
S
Y
F
S
V
G
P
T
Site 5
Y10
S
S
S
S
S
N
S
Y
F
S
V
G
P
T
S
Site 6
S12
S
S
S
N
S
Y
F
S
V
G
P
T
S
P
S
Site 7
S17
Y
F
S
V
G
P
T
S
P
S
A
V
V
L
L
Site 8
S46
L
E
E
R
R
H
V
S
D
L
K
F
A
M
K
Site 9
Y60
K
C
Y
T
P
L
V
Y
K
G
I
T
P
C
K
Site 10
S74
K
P
I
D
I
K
C
S
V
L
N
S
E
E
I
Site 11
Y83
L
N
S
E
E
I
H
Y
V
I
K
Q
L
S
K
Site 12
S89
H
Y
V
I
K
Q
L
S
K
E
S
L
Q
S
V
Site 13
S95
L
S
K
E
S
L
Q
S
V
D
V
L
R
E
E
Site 14
S111
S
E
I
L
D
E
M
S
H
K
L
R
L
G
A
Site 15
T212
G
A
F
F
M
R
R
T
F
G
G
N
K
L
Y
Site 16
Y219
T
F
G
G
N
K
L
Y
W
A
V
F
S
E
Y
Site 17
Y226
Y
W
A
V
F
S
E
Y
V
K
T
M
L
R
N
Site 18
T229
V
F
S
E
Y
V
K
T
M
L
R
N
G
Y
A
Site 19
S247
F
F
L
E
G
T
R
S
R
S
A
K
T
L
T
Site 20
S249
L
E
G
T
R
S
R
S
A
K
T
L
T
P
K
Site 21
T252
T
R
S
R
S
A
K
T
L
T
P
K
F
G
L
Site 22
T254
S
R
S
A
K
T
L
T
P
K
F
G
L
L
N
Site 23
T291
Y
D
K
I
L
E
E
T
L
Y
V
Y
E
L
L
Site 24
S318
L
K
A
R
K
I
L
S
E
N
F
G
S
I
H
Site 25
S336
G
D
P
V
S
L
R
S
L
A
A
G
R
M
S
Site 26
S343
S
L
A
A
G
R
M
S
R
S
S
Y
N
L
V
Site 27
S345
A
A
G
R
M
S
R
S
S
Y
N
L
V
P
R
Site 28
S346
A
G
R
M
S
R
S
S
Y
N
L
V
P
R
Y
Site 29
Y347
G
R
M
S
R
S
S
Y
N
L
V
P
R
Y
I
Site 30
Y353
S
Y
N
L
V
P
R
Y
I
P
Q
K
Q
S
E
Site 31
T502
V
A
V
A
L
Q
M
T
P
G
F
R
K
E
D
Site 32
Y511
G
F
R
K
E
D
V
Y
S
C
F
R
F
L
R
Site 33
Y541
K
D
F
E
E
G
C
Y
L
L
C
K
S
E
A
Site 34
S579
L
F
K
P
F
V
E
S
Y
Q
I
I
C
K
Y
Site 35
Y586
S
Y
Q
I
I
C
K
Y
L
L
S
E
E
E
D
Site 36
S589
I
I
C
K
Y
L
L
S
E
E
E
D
H
F
S
Site 37
S596
S
E
E
E
D
H
F
S
E
E
Q
Y
L
A
A
Site 38
Y600
D
H
F
S
E
E
Q
Y
L
A
A
V
R
K
F
Site 39
T608
L
A
A
V
R
K
F
T
S
Q
L
L
D
Q
G
Site 40
T616
S
Q
L
L
D
Q
G
T
S
Q
C
Y
D
V
L
Site 41
S617
Q
L
L
D
Q
G
T
S
Q
C
Y
D
V
L
S
Site 42
Y620
D
Q
G
T
S
Q
C
Y
D
V
L
S
S
D
V
Site 43
S624
S
Q
C
Y
D
V
L
S
S
D
V
Q
K
N
A
Site 44
S625
Q
C
Y
D
V
L
S
S
D
V
Q
K
N
A
L
Site 45
T670
E
E
M
L
G
C
K
T
P
I
G
K
P
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation